The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
ESR evidence for the hydroxyl radical formation in aqueous suspension of quartz particles and its possible significance to lipid peroxidation in silicosis
Abstract
Electron spin resonance (ESR) spectrum of the hydroxyl (.OH) radical spin adduct with the spin trap 5,5-dimethyl-1-pyrroline-N-oxide has been obtained in suspensions of freshly ground quartz particles. The concentration of the spin adduct (and hence of the .OH radicals) increases with the amount of grinding. The dust's potential for the generation of the .OH radicals is maximum when fresh (i.e., immediately after grinding) and decreases to 50% in about a day on storage in air. Studies involving metal chelates indicate that the .OH radical formation involves mainly the silica surface and H2O rather than the Fenton reaction. The results suggest that hydroxyl radical reaction(s) could be important in the lipid peroxidation and fibrogenicity by quartz dust, particularly in acute silicosis.
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“Moreover, surface reactivity with the generation of free radicals [324–328], and their ability to induce the peroxidation of cellular lipids were also studied [329–334].”
From Particle toxicology and health - where are we? (2019) · cites this paper as [331]
Citations
Cites
Asbestos catalyzes hydroxyl and superoxide radical generation from hydrogen peroxide
Weitzman, S. A., & Graceffa, P. (1984) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(84)90078-x · Cited by 292
Research works printed but not linked: 17
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Cited by
Sorted by citations
Silica binding and toxicity in alveolar macrophages
Hamilton, R. F., Thakur, S. A., & Holian, A. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.12.027 · Cited by 415
Particle toxicology and health - where are we?
Riediker, M., Zink, D., Kreyling, W., Oberdörster, G., Elder, A., Graham, U., Lynch, I., Duschl, A., Ichihara, G., Ichihara, S., et al. (2019) · Particle and Fibre Toxicology · doi:10.1186/s12989-019-0302-8 · Cited by 237
Generation of oxygen radicals by minerals and its correlation to cytotoxicity.
Vallyathan, V (1994) · Environmental Health Perspectives · doi:10.1289/ehp.94102s10111 · Cited by 66
Self-citationGeneration of Reactive Oxygen Species by Quartz Particles and Its Implication for Cellular Damage
Shi, X., Mao, Y., Danie, L. N., Saffiotti, U., Dalal, N. S., & Vallyathan, V. (1995) · Applied Occupational and Environmental Hygiene · doi:10.1080/1047322x.1995.10389108 · Cited by 47
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Metadata
- Authors
- Shi, X., Dalai, N. S., & Vallyathan, V.
- Venue
- Journal of Toxicology and Environmental Health
- Publisher
- Informa UK Limited
- Published
- 1988-10-01
- Volume
- 25
- Issue
- 2
- Pages
- 237-245
- ISSN
- 0098-4108
- Cited by
- 79
- References
- 1
- Language
- en
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- Shi, X., Dalai, N. S., & Vallyathan, V. (1988). ESR evidence for the hydroxyl radical formation in aqueous suspension of quartz particles and its possible significance to lipid peroxidation in silicosis. Journal of Toxicology and Environmental Health. https://doi.org/10.1080/15287398809531205
