Evidence-Based Comprehensive Treatments for Early Autism
Open accessAbstract
Early intervention for children with autism is currently a politically and scientifically complex topic. Randomized controlled trials have demonstrated positive effects in both short-term and longer term studies. The evidence suggests that early intervention programs are indeed beneficial for children with autism, often improving developmental functioning and decreasing maladaptive behaviors and symptom severity at the level of group analysis. Whether such changes lead to significant improvements in terms of greater independence and vocational and social functioning in adulthood is also unknown. Given the few randomized controlled treatment trials that have been carried out, the few models that have been tested, and the large differences in interventions that are being published, it is clear that the field is still very early in the process of determining (a) what kinds of interventions are most efficacious in early autism, (b) what variables moderate and mediate treatment gains and improved outcomes following intervention, and (c) the degree of both short-term and long-term improvements that can reasonably be expected. To examine these current research needs, the empirical studies of comprehensive treatments for young children with autism published since 1998 were reviewed. Lovaas's treatment meet Chambless and colleague's (Chambless et al., 1998; Chambless et al., 1996) criteria for "well-established" and no treatment meets the "probably efficacious" criteria, though three treatments meet criteria for "possibly efficacious" (Chambless & Hollon, 1998). Most studies were either Type 2 or 3 in terms of their methodological rigor based on Nathan and Gorman's (2002) criteria. Implications of these findings are also discussed in relation to practice guidelines as well as critical areas of research that have yet to be answered.
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Receiving a diagnosis early and starting intensive treatment is linked to more favorable outcomes for every child with ASD.
“A series of studies (Ben-Itzchak, Lahat, Burgin, & Zachor, 2008; Dawson et al., 2009; Rogers & Vismara, 2008) have now demonstrated that early identification and intensive early intervention are associated with more favorable outcomes for all children with ASDs.”
From Sensitivity and Specificity of Proposed DSM-5 Criteria for Autism Spectrum Disorder in Toddlers (2013) · cites this paper as Rogers & Vismara, 2008
In “Treatments for Early Autism” (page unavailable), the review reports better outcomes among children who began treatment younger and developmental gains among groups receiving focused interventions. But the “Sallows and Graupner (2005)” section reports poor outcomes for about half the children despite years of intensive treatment. The source therefore supports an association for some children or groups, not the claim of favorable outcomes for every child with ASD. (LLM, conf=0.88)
Experimental — accuracy not yet measuredEarly intervention is effective in decreasing impairments and may improve long-term outcomes for children with ASD.
“Early intervention is effective in decreasing impairments (Dawson et al ., 2010) and may result in more positive long-term outcomes for the child (Rogers and Vismara, 2008).”
From Early brain enlargement and elevated extra-axial fluid in infants who develop autism spectrum disorder (2013) · cites this paper as Rogers and Vismara, 2008
Intensive early intervention can improve cognitive, language, and adaptive behavior in children with ASDs.
“Studies have demonstrated that intensive, early intervention programs can improve cognitive and language abilities and adaptive behavior in children with ASDs (Dawson et al., 2010; Rogers and Vismara, 2008; Vismara and Rogers, 2010).”
From Explaining differences in age at autism spectrum disorder diagnosis: A critical review (2014) · cites this paper as Rogers and Vismara, 2008
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References 115 · Cited by 984
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- Authors
- Rogers, S. J., & Vismara, L. A.
- Affiliations
- University of California, Davis (US)
- Corresponding author
- Rogers, Sally J.
- Venue
- Journal of Clinical Child & Adolescent Psychology
- Publisher
- Informa UK Limited
- Published
- 2008-03-03
- Volume
- 37
- Issue
- 1
- Pages
- 8-38
- ISSN
- 1537-4416 (ISSN-L)
- 1537-4424
- PMC
- PMC2943764
- OpenAlex
- W2026674010
- Cited by
- 984
- References
- 115
- Citations by year
- 2026: 18 · 2025: 35 · 2024: 22 · 2023: 39 · 2022: 50 · 2021: 41 · 2020: 47 · 2019: 38 · 2018: 50 · 2017: 56 · 2016: 52 · 2015: 75 · 2014: 90 · 2013: 82 · 2012: 92
- FWCI
- 33.59
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- public-domain
- Locations
- Journal of Clinical Child & Adolescent Psychology (publishedVersion, public-domain)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (5r01mh068232-04)
- National Institute of Mental Health (R01 MH0683981, R01-MH068232, R13 MH70772-01, R21 MH0673631, T32MH073124, R01 MH068232-01, MH073124, R13MH070772)
- National Institute on Deafness and Other Communication Disorders (R21DC005574, R21 DC05574-03)
- National Institute of Child Health and Human Development
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U19HD035468, U19 HD35468-07)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Developmental and Educational Psychology › Behavioral and Psychological Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- autism spectrum disorder, early intervention, comprehensive treatment, long-term outcomes, methodological quality, clinical guidelines, young children
- MeSH terms
- Autistic Disorder, Behavior Therapy, Child, Preschool, Combined Modality Therapy, Education, Family Therapy, Humans, Psychotherapy, Randomized Controlled Trials as Topic, Early Intervention, Educational, Evidence-Based Medicine
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