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Loss of MD1 Promotes Inflammatory and Apoptotic Atrial Remodelling in Diabetic Cardiomyopathy by Activating the TLR4/NF-κB Signalling Pathway

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pNaktide mitigates inflammation-induced neuronal damage and behavioral deficits through the oxidative stress pathway

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Sleep deprivation activated AMPK/FOXO3a signaling mediates pineal autophagy impairment to reduce melatonin secretion in CUMS + SD rats leading to depression combined with insomnia

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Autophagy-targeted Pt( iv ) agents: a new horizon in antitumor drug development

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Piracetam-induced neuroprotection in lipopolysaccharides-challenged EOC-20 cells and mouse brain via attenuating oxidative stress

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TLR4 inhibited autophagy by modulating PI3K/AKT/mTOR signaling pathway in Gastric cancer cell lines

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Developing Humanized Animal Models with Transplantable Human iPSC-Derived Cells

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Biflavonoid Methylchamaejasmin and Khaya grandifoliola Extract Inhibit NLRP3 Inflammasome in THP-1 Cell Model of Neuroinflammation

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Distinct UPR and Autophagic Functions Define Cell-Specific Responses to Proteotoxic Stress in Microglial and Neuronal Cell Lines

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Comprehensive Bioinformatics Analysis of Lipopolysaccharide‐Induced Altered Autophagy in Acute Lung Injury and Construction of Underlying Competing Endogenous RNA Regulatory Mechanism

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Absence of MerTK Disrupts Spermatogenesis in an Age-Dependent Manner

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Jasminoidin and ursodeoxycholic acid exert synergistic effect against cerebral ischemia-reperfusion injury via Dectin-1-induced NF-κB activation pathway.

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Autophagy activation alleviates the LPS‐induced inflammatory response in endometrial epithelial cells in dairy cows

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microRNA-132 attenuates inflammation in induced pluripotent stem cell-derived microglia from Alzheimer’s disease patients

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Treponema pallidum Flagellin FlaB3 Activates Inflammation and Inhibits Autophagy in HMC3 Cells via the TLR4 Pathway

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Role of Microglial Dysfunction in Parkinson’s Disease: From Multifactorial Causes to Neurodegeneration

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Single-nucleus epigenomic profiling of the adult human central nervous system unveils epigenetic memory of developmental programs

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Histone lysine demethylase 3B regulates autophagy via transcriptional regulation of GABARAPL1 in acute myeloid leukemia cells

Song, Y. Q., Zhang, J., Wang, H., Wang, H., Liu, Y., & Hu, Z. (2023) · International Journal of Oncology · doi:10.3892/ijo.2023.5535 · Cited by 6

PPP1R15A Promotes Apoptosis, Autophagy, and Inflammatory Response to Exacerbate Ischemic Stroke Through Activation of TLR4 / NF ‐ κB Pathway

Liu, L., Li, J., Yin, P., Kong, S., & Li, J. (2025) · Journal of Neuroscience Research · doi:10.1002/jnr.70073 · Cited by 5

Lactate Ameliorates Kainic Acid-Induced Neuroinflammation and Cognitive Impairment via the Chemokine Signaling Pathway in Mice

Chu, X., Ge, Y., Geng, C., Cao, P., Wei, P., Fu, B., Deng, Z., Li, Y., & Zhao, G. (2025) · Journal of Inflammation Research · doi:10.2147/jir.s498738 · Cited by 5

Microglial Autophagic Dysregulation in Traumatic Brain Injury: Molecular Insights and Therapeutic Avenues

Bano, N., Khan, S., Ahamad, S., Dar, N. J., Alanazi, H. H., Nazir, A., & Bhat, S. A. (2025) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.4c00617 · Cited by 6

Wnt1 oversees microglial activation by the Wnt/LRP5/6 receptor signaling pathway during lipopolysaccharide-mediated toxicity

Qing, W., Xu, H., Xuan, S., Zhihui, R., & Jinzhi, G. (2025) · Molecular Biology Reports · doi:10.1007/s11033-025-10360-2 · Cited by 4

TFEB, FOXO3 and TLR4 in resveratrol-induced autophagy in a mucopolysaccharidosis IIIB mouse model

Rintz, E., Podlacha, M., Gaffke, L., Jerzemowska, G., Cyske, Z., Pierzynowska, K., & Węgrzyn, G. (2026) · Experimental & Molecular Medicine · doi:10.1038/s12276-026-01643-0 · Cited by 5

Bafilomycin 1A Affects p62/SQSTM1 Autophagy Marker Protein Level and Autophagosome Puncta Formation Oppositely under Various Inflammatory Conditions in Cultured Rat Microglial Cells

Pesti, I., Barczánfalvi, G., Dulka, K., Kata, D., Farkas, E., & Gulya, K. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25158265 · Cited by 4

Massively Parallel Screening of Toll/Interleukin‐1 Receptor (TIR)‐Derived Peptides Reveals Multiple Toll‐Like Receptors (TLRs)‐Targeting Immunomodulatory Peptides

Lim, Y., Kang, T. K., Kim, M. I., Kim, D., Kim, J. Y., Jung, S. H., Park, K., Lee, W., & Seo, M. (2024) · Advanced Science · doi:10.1002/advs.202406018 · Cited by 4

Intracellular and intercellular crosstalk between exosomes and autophagy

Li, Q., Chen, S., Yin, Y., Han, M., Shi, H., Gong, Y. L., Duan, X., Wang, Y., Guo, Q., Duan, Y., et al. (2025) · The Innovation Life · doi:10.59717/j.xinn-life.2025.100132 · Cited by 4

Intermittent Lipopolysaccharide Exposure Significantly Increases Cortical Infarct Size and Impairs Autophagy

Russell, A. E., Cavendish, J. Z., Rai, A., Vannoy, M., Dakhlallah, A., Hu, H., Ren, X. S., Amer, A. O., Brown, C. M., Marsh, C. B., et al. (2021) · ASN NEURO · doi:10.1177/1759091421991769 · Cited by 4

Neuroinflammation-Modulating Agent SB1617 Enhances LC3-Associated Phagocytosis to Mitigate Tau Pathology

Cho, H., Choi, B. Y., Shin, Y., Suh, S. W., & Park, S. B. (2023) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00508 · Cited by 4

Cx3cr1CreERT2-driven Atg7 deletion in adult mice induces intestinal adhesion

Lee, Y., Lee, J., Nam, H., & Yu, S. (2020) · Molecular Brain · doi:10.1186/s13041-020-00630-4 · Cited by 4

The autophagy activator Spermidine ameliorates Alzheimer’s disease pathology and neuroinflammation in micePreprint

Freitag, K., Sterczyk, N., Schulz, J., Houtman, J., Fleck, L., Sigrist, S. J., Heppner, F. L., & Jendrach, M. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.27.424477 · Cited by 4

Targeting pattern recognition receptors for cancer therapy: Mechanisms and strategies

Ouyang, D., Chen, R., Xie, H., Yang, X., Li, Q., & Chen, J. (2025) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2025.09.007 · Cited by 3

SIRT2 Inhibition promotes microglia LC3-associated phagocytosis via NRF2/CD36 after the experimental subarachnoid hemorrhage

Sheng, B., Chen, X., tao, T., Sun, J.-Q., Li, W., Wu, L., Peng, Z., Li, X., Zhou, Z., Yu, Q., et al. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03623-z · Cited by 3

DRP1 induces neuroinflammation via transcriptional regulation of NF-ĸB.

Lai, Y., Fan, R. Z., Brown, H. J., Salehe, S. S., Tieu, E. K., & Tieu, K. (2026) · Nature Communications · doi:10.1038/s41467-026-70780-x · Cited by 3

Inflammation increases the penetrance of behavioral impairment in Shank3 haploinsufficiency mice — can it explain the behavioral regression in Autism?

Qiao, S.-N., Wang, S. E., Kim, K.-Y., Jo, S., & Jiang, Y.-H. (2026) · Molecular Psychiatry · doi:10.1038/s41380-026-03534-2 · Cited by 5

TLR4 mediates post-traumatic depression via kynurenine pathway activation in a murine traumatic brain injury model

Li, C.-H., Wang, B., Gao, R., Peng, Y., Chen, K., Li, X.-H., & Li, P. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1744031 · Cited by 3

Studying Autophagy in Microglia: Overcoming the Obstacles

Plaza‐Zabala, A., & Sierra, A. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3437-0_3 · Cited by 3

NLRP3 Inflammasome Simultaneously Involved in Autophagy and Phagocytosis of THP-1 Cells to Clear Aged Erythrocytes

Li, Q., Zhao, F., Zhang, J., Yang, Y. N., Guo, Z., Wang, C., Yang, Q., Sun, Y., & Zhu, Z. (2022) · Journal of Immunology Research · doi:10.1155/2022/1481154 · Cited by 3

Evaluation of in vitro colonisation and immunomodulation of Lactiplantibacillus plantarum L3 microcapsules after subjected to yoghurt storage

Gao, J., Hu, Y., Yan, S., Qi, F., Li, X., & Sun, Q. (2024) · International Journal of Food Science & Technology · doi:10.1111/ijfs.17188 · Cited by 3

Analysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibilityPreprint

Zou, J., Gopalakrishnan, S., Parker, C. C., Nicod, J., Mott, R., Cai, N., Lionikas, A., Davies, R. W., Palmer, A. A., & Jonathan Flint, C. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.02.05.429998 · Cited by 3

Suppression of autophagy through TLR4/PI3K/FoxO3 signaling impairs phagocytic degradation of microglia

Nam, H. (2018) · doi:10.22677/thesis.200000006128

Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation

Ye, X., Zhu, M., Che, X., Wang, H., Liang, X., Wu, C., Xue, X., & Yang, J. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1644-8 · Cited by 189

p38 MAPK inhibits autophagy and promotes microglial inflammatory responses by phosphorylating ULK1

He, Y., She, H., Zhang, T., Xu, H., Cheng, L., Yepes, M., Zhao, Y., & Mao, Z. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201701049 · Cited by 293

T oll‐like receptor‐4‐mediated autophagy contributes to microglial activation and inflammatory injury in mouse models of intracerebral haemorrhage

Yang, Z., Liu, B., Zhong, L., Shen, H., Lin, C., Lin, L., Zhang, N., & Yuan, B. (2014) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12177 · Cited by 56

Activation of Autophagy Pathway Suppresses the Expression of iNOS, IL6 and Cell Death of LPS-Stimulated Microglia Cells

Han, H.-E., Kim, T., Son, H.-J., Park, W. J., & Han, P. (2013) · Biomolecules & Therapeutics · doi:10.4062/biomolther.2012.089 · Cited by 86