CoChat
Sign Up
Cited by 5,594

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

Brunet, Anne, Bonni, Azad, Zigmond, Michael J, Lin, Michael Z, Juo, Peter, Hu, Linda S, Anderson, Michael J, Arden, Karen C, Blenis, John, Greenberg, Michael E·1999·Cell
DOI 10.1016/s0092-8674(00)80595-4
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/s0092-8674(00)80595-4

Cites

3 of 3 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 40

  1. Alessi, 1996, Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase, FEBS Lett., 399, 333, 10.1016/S0014-5793(96)01370-1 · DOI · Paper page
  2. Anderson, 1998, Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily, Genomics, 47, 187, 10.1006/geno.1997.5122 · DOI
  3. Andjelkovic, 1997, Role of translocation in the activation and function of protein kinase B, J. Biol. Chem., 272, 31515, 10.1074/jbc.272.50.31515 · DOI · Paper page
  4. Borkhardt, 1997, Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23), Oncogene, 14, 195, 10.1038/sj.onc.1200814 · DOI
  5. Cardone, 1998, Regulation of cell death protease caspase-9 by phosphorylation, Science, 282, 1318, 10.1126/science.282.5392.1318 · DOI · Paper page
  6. Cichy, 1998, Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequence, J. Biol. Chem., 273, 6482, 10.1074/jbc.273.11.6482 · DOI
  7. Datta, 1998, Molecular mechanisms of neuronal survival and apoptosis, Horm. Signaling, 1, 257, 10.1016/B978-012312411-1/50010-X · DOI
  8. Datta, 1997, Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery, Cell, 91, 231, 10.1016/S0092-8674(00)80405-5 · DOI · Paper page
  9. del Peso, 1997, Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt, Science, 278, 687, 10.1126/science.278.5338.687 · DOI · Paper page
  10. Downward, 1998, Mechanisms and consequences of activation of protein kinase B/Akt, Curr. Opin. Cell Biol., 10, 262, 10.1016/S0955-0674(98)80149-X · DOI
  11. Dudek, 1997, Regulation of neuronal survival by the serine-threonine protein kinase Akt, Science, 275, 661, 10.1126/science.275.5300.661 · DOI · Paper page
  12. Faris, 1998, The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression, J. Immunol., 160, 134, 10.4049/jimmunol.160.1.134 · DOI
  13. Friesen, 1996, Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells, Nat. Med., 2, 574, 10.1038/nm0596-574 · DOI
  14. Fruman, 1998, Phosphoinositide kinases, Annu. Rev. Biochem., 67, 481, 10.1146/annurev.biochem.67.1.481 · DOI
  15. Galili, 1993, Fusion of a forkhead domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma, Nat. Genet., 5, 230, 10.1038/ng1193-230 · DOI
  16. Hillion, 1997, AF6q21, a novel partner of the MLL gene in t(6;11)(q21;q23), defines a forkhead transcriptional factor subfamily, Blood, 90, 3714, 10.1182/blood.V90.9.3714 · DOI
  17. Holtz-Heppelmann, 1998, Transcriptional regulation of the human FasL promoter-enhancer region, J. Biol. Chem., 273, 4416, 10.1074/jbc.273.8.4416 · DOI
  18. Jacobson, 1997, Programmed cell death in animal development, Cell, 88, 347, 10.1016/S0092-8674(00)81873-5 · DOI
  19. Kauffmann-Zeh, 1997, Suppression of the c-Myc-induced apoptosis by Ras signaling through PI(3)K and PKB, Nature, 385, 544, 10.1038/385544a0 · DOI
  20. Kaufmann, 1995, DNA recognition site analysis of Xenopus winged helix proteins, J. Mol. Biol., 248, 239, 10.1016/S0022-2836(95)80047-6 · DOI
  21. Kennedy, 1997, The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal, Genes Dev., 11, 701, 10.1101/gad.11.6.701 · DOI
  22. Khanna, 1993, Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells, Oncogene, 8, 3307
  23. Latinis, 1997, Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells, J. Biol. Chem., 272, 31427, 10.1074/jbc.272.50.31427 · DOI
  24. Le-Niculescu, 1999, Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death, Mol. Cell Biol., 19, 751, 10.1128/MCB.19.1.751 · DOI
  25. Liao, 1998, Activation of protein kinase B/Akt is sufficient to repress the glucocorticoid and cAMP induction of phosphoenolpyruvate carboxykinase gene, J. Biol. Chem., 273, 27320, 10.1074/jbc.273.42.27320 · DOI
  26. Lin, 1997, daf-16, Science, 278, 1319, 10.1126/science.278.5341.1319 · DOI
  27. Mittelstadt, 1998, Cyclosporin A-sensitive transcription factor Egr-3 regulates Fas ligand expression, Mol. Cell Biol., 18, 3744, 10.1128/MCB.18.7.3744 · DOI
  28. Miyashita, 1995, Tumor suppressor p53 is a direct transcriptional activator of the human bax gene, Cell, 80, 293, 10.1016/0092-8674(95)90412-3 · DOI · Paper page
  29. Nagata, 1997, Apoptosis by death factor, Cell, 88, 355, 10.1016/S0092-8674(00)81874-7 · DOI
  30. O’Brien, 1995, Hepatic nuclear factor 3- and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes, Mol. Cell Biol., 15, 1747, 10.1128/MCB.15.3.1747 · DOI
  31. Ogg, 1997, The Forkhead transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans, Nature, 389, 994, 10.1038/40194 · DOI
  32. Pagès, 1994, Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1), EMBO J., 13, 3003, 10.1002/j.1460-2075.1994.tb06599.x · DOI
  33. Paradis, 1998, Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor, Genes Dev., 12, 2488, 10.1101/gad.12.16.2488 · DOI
  34. Pierrou, 1994, Cloning and characterization of seven human forkhead proteins, EMBO J., 13, 5002, 10.1002/j.1460-2075.1994.tb06827.x · DOI
  35. Sakamaki, 1998, Molecular cloning and characterization of mouse caspase-8, Eur. J. Biochem., 253, 399, 10.1046/j.1432-1327.1998.2530399.x · DOI
  36. Songyang, 1997, Interleukin 3-dependent survival by the Akt protein kinase, Proc. Natl. Acad. Sci. USA, 94, 11345, 10.1073/pnas.94.21.11345 · DOI
  37. Steller, 1995, Mechanisms and genes of cellular suicide, Science, 267, 1445, 10.1126/science.7878463 · DOI
  38. Sung, 1991, Tumor necrosis factor-alpha mRNA accumulation in human myelomonocytic cell lines. Role of transcriptional regulation by DNA sequence motifs and mRNA stabilization, J. Immunol., 147, 2047, 10.4049/jimmunol.147.6.2047 · DOI
  39. Yaffe, 1997, The structural basis for 14-3-3:phosphopeptide binding specificity, Cell, 91, 961, 10.1016/S0092-8674(00)80487-0 · DOI
  40. Yano, 1998, Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway, Nature, 396, 584, 10.1038/25147 · DOI

Cited by

Sorted by citations

Metadata

Authors
Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J., & Greenberg, M. E.
Venue
Cell
Publisher
Elsevier BV
Published
1999-03
Volume
96
Issue
6
Pages
857-868
ISSN
0092-8674
DOI
10.1016/s0092-8674(00)80595-4
Cited by
5,594
References
3
Language
en
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review