Cited by 194Posttraumatic Stress Disorder ResearchAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychotherapy Techniques and Applications

The DOI matches its Crossref record; 121 of the 121 references it cites were found in a registry or an index.

Exercise Augmentation of Exposure Therapy for PTSD: Rationale and Pilot Efficacy Data

Open access

Powers, Mark B., Medina, Johnna L., Burns, Stephanie, Kauffman, Brooke Y., Monfils, Marie, Asmundson, Gordon J.G., Diamond, Allison, McIntyre, Christa, Smits, Jasper A.J.·2015·Cognitive Behaviour Therapy

DOI 10.1080/16506073.2015.1012740PMC PMC4464974

Open this paper in CoChat — free account

Abstract

Brain-derived neurotrophic factor (BDNF) is associated with synaptic plasticity, which is crucial for long-term learning and memory. Some studies suggest that people suffering from anxiety disorders show reduced BDNF relative to healthy controls. Lower BDNF is associated with impaired learning, cognitive deficits, and poor exposure-based treatment outcomes. A series of studies with rats showed that exercise elevates BDNF and enhances fear extinction. However, this strategy has not been tested in humans. In this pilot study, we randomized participants (N = 9, 8 females, M(Age) = 34) with posttraumatic stress disorder (PTSD) to (a) prolonged exposure alone (PE) or (b) prolonged exposure+exercise (PE+E). Participants randomized to the PE+E condition completed a 30-minute bout of moderate-intensity treadmill exercise (70% of age-predicted HR(max)) prior to each PE session. Consistent with prediction, the PE+E group showed a greater improvement in PTSD symptoms (d = 2.65) and elevated BDNF (d = 1.08) relative to the PE only condition. This pilot study provides initial support for further investigation into exercise augmented exposure therapy.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1080/16506073.2015.1012740

Cites

121 of 121 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Journal of Clinical Psychiatry
(2018) · Journal of Clinical Psychiatry · doi:10.5505/kpd · Cited by 13,703
Untitled work
(2014) · Medical Entomology and Zoology · Cited by 9,400
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
Lang, U. E., & Borgwardt, S. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350094 · Cited by 8,526
Translational Findings on Brain-Derived Neurotrophic Factor and Anxiety: Contributions from Basic Research to Clinical Practice
da Luz, A. C. D. D. S., Dias, G. P., Bevilaqua, M. C. D. N., Cocks, G. D., Gardino, P. F., Thuret, S., & Nardi, A. E. (2013) · Neuropsychobiology · doi:10.1159/000353269 · Cited by 4,015
Structured Clinical Interview for DSM-IV Axis I Disorders
Spitzer, R. L., First, M. B., & Gibbon, M. (1997) · Medical Entomology and Zoology · Cited by 3,582
Functional Neuroimaging of Anxiety: A Meta-Analysis of Emotional Processing in PTSD, Social Anxiety Disorder, and Specific Phobia
Etkin, A., & Wager, T. D. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07030504 · Cited by 3,391 · cited 1×
“In particular, hyperreactivity is seen in the amygdala (Nutt & Malizia, 2004) and decreased activity is exhibited in the ventromedial prefrontal cortex (vmPFC; Etkin & Wager, 2007) in individuals suffering from PTSD. Hippocampal volume and metabolic rate are also reduced in PTSD (Smith, 2005).”
Background
The Nerve Growth Factor 35 Years Later
Levi‐Montalcini, R. (1987) · Science · doi:10.1126/science.3306916 · Cited by 3,109
Exercise: a behavioral intervention to enhance brain health and plasticity
Cotman, C. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02143-4 · Cited by 2,739
Reliability and validity of a brief instrument for assessing post-traumatic stress disorder
Foa, E. B., Riggs, D. S., Dancu, C. V., & Rothbaum, B. O. (1993) · Journal of Traumatic Stress · doi:10.1002/jts.2490060405 · Cited by 2,537
Extinction Learning in Humans
Phelps, E. A., Delgado, M. R., Nearing, K. I., & LeDoux, J. E. (2004) · Neuron · doi:10.1016/j.neuron.2004.08.042 · Cited by 1,753

Show all 120 references

Research works printed but not linked: 3

Pavlov, I. (1927). Conditional reflex: an investigation of the psychological activity of the cerebral cortex. New York, NY: Oxford University Press.
Pitman R.K., 2001, The Journal of Clinical Psychiatry, 62, 47
Powers, M.B., Vervliet, B., Smits, J.A.J. & Otto, M.W. (2009). Helping exposure succeed: Leaning theory perspectives on treatment resistance and relapse. In M.M. Antony, S.G. Hofmann, & M.W. Otto (Eds.), Resolving treatment complications in anxiety disorders (pp. 31–50). New York, NY: Springer.

Sorted by citations

Items 101–194 of 194

Gardening activity and its relationship to mental health: Understudied and untapped in low-and middle-income countries
Ainamani, H., Gumisiriza, N., Bamwerinde, W. M., & Rukundo, G. Z. (2022) · Preventive Medicine Reports · doi:10.1016/j.pmedr.2022.101946 · Cited by 12
Technology-enhanced in vivo exposures in Prolonged Exposure for PTSD: A pilot randomized controlled trial
Saraiya, T. C., Jarnecke, A. M., Rothbaum, A. O., Wangelin, B. C., McTeague, L. M., Acierno, R. E., Brown, D. G., Bristol, E., Feigl, H., Reese, M., et al. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.10.056 · Cited by 11
Adjunctive cognitive training with exposure enhances fear and neural outcomes in social anxiety
Caudle, M. M., Dugas, N., Stout, D. M., Ball, T. M., & Bomyea, J. A. (2023) · Psychiatry Research · doi:10.1016/j.psychres.2023.115416 · Cited by 11
Improvements in cardiorespiratory fitness are not significantly associated with post-traumatic stress disorder symptom reduction in intensive treatment
Voorendonk, E. M., Sanches, S. A., de Jongh, A., & van Minnen, A. (2019) · European Journal of Psychotraumatology · doi:10.1080/20008198.2019.1654783 · Cited by 12
Combining a single session of prolonged exposure with physical activity in patients with PTSD: The effect of sequence
Voorendonk, E. M., Sanches, S. A., Mojet, M., de Jongh, A., & van Minnen, A. (2021) · Mental health and physical activity · doi:10.1016/j.mhpa.2021.100417 · Cited by 11
Brain derived neurotrophic factor and treatment outcomes among veterans attending an intensive treatment program for posttraumatic stress disorder
Zalta, A. K., Voigt, R. M., Stevens, S., Held, P., Raeisi, S., Boley, R. A., Keshavarzian, A., & Pollack, M. H. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.02.045 · Cited by 10
Prophylactic relationship between mental health disorder symptoms and physical activity of Royal Canadian Mounted Police Cadets during the cadet training program
Teckchandani, T. A., Krakauer, R. L., Andrews, K. L., Neary, J. P., Nisbet, J., Shields, R. E., Maguire, K. Q., Jamshidi, L., Afifi, T. O., Lix, L. M., et al. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1145184 · Cited by 10
Predictors of Unbearability, Unlovability, and Unsolvability in Veterans With Military-Sexual-Trauma-Related Posttraumatic Stress Disorder
Wiblin, J. L., Holder, N. D., Holliday, R. P., & Surís, A. (2018) · Journal of Interpersonal Violence · doi:10.1177/0886260518777554 · Cited by 10
Anxiety Sensitivity is Associated with Lower Enjoyment and an Anxiogenic Response to Physical Activity in Smokers
Farris, S. G., Legasse, A. J., Uebelacker, L. A., Brown, R. A., Price, L. H., & Abrantes, A. M. (2018) · Cognitive Therapy and Research · doi:10.1007/s10608-018-9948-z · Cited by 12
Does raising heart rate prior to a behavioural test enhance learning in cognitive therapy for anxiety? An experimental test for the treatment of fear of heights using virtual reality
McInerney, J., Brown, P., Bird, J. C., Nickless, A., Brown, G. P., & Freeman, D. H. (2021) · Behaviour Research and Therapy · doi:10.1016/j.brat.2021.103928 · Cited by 12
Working it out: acute exercise to combat anxiety and depressive symptoms in individuals living with subsyndromal post-traumatic stress disorder
Greene, D. R., & Petruzzello, S. J. (2021) · International Journal of Sport and Exercise Psychology · doi:10.1080/1612197x.2021.1979075 · Cited by 9
Physical Activity and Exercise as a Tool to Cure Anxiety and Posttraumatic Stress Disorder
Sabri, S., Rashid, N., & Mao, Z. (2023) · Mental Illness · doi:10.1155/2023/4294753 · Cited by 12
Sport, Stress und Gesundheit
Gerber, M. (2019) · Springer eBooks · doi:10.1007/978-3-662-56802-6_25 · Cited by 9
Precision-based exercise in people with anxiety and stress related disorders: Are there interindividual differences in anxiolytic effects? An ancillary meta-analysis of randomized controlled trials
Vancampfort, D., Heißel, A., Waclawovsky, A. J., Stubbs, B., Firth, J., McGrath, R. L., Damme, T. V., & Schuch, F. B. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114803 · Cited by 8
Out with the bad, in with the good: A review on augmented extinction learning in humans
Bauer, E., Laing, P. A. F., Cooper, S. E., Cisler, J. M., & Dunsmoor, J. E. (2024) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2024.107994 · Cited by 9
Changes in brain-derived neurotropic factor following aerobic exercise
Curtis, R., Blades, A., Moris, J. M., & Koh, Y. (2024) · Sport Sciences for Health · doi:10.1007/s11332-024-01244-2 · Cited by 11
The impact of physical exercise on the consolidation of fear extinction memories
Jentsch, V. L., Wolf, O. T., Otto, T., & Merz, C. J. (2023) · Psychophysiology · doi:10.1111/psyp.14373 · Cited by 8
Cognitive-Behavioral Therapy Enhancement Strategies
Tolin, D. F., Lord, K. A., & Knowles, K. A. (2024) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2024.02.005 · Cited by 7
The therapeutic potential of exercise in post-traumatic stress disorder and its underlying mechanisms: A living systematic review of human and non-human studies
Wright, S. L., Chiocchia, V., Elugbadebo, O. O., Ouma, S., Furukawa, T. A., Friedrich, C., Austin, C., Dehdarirad, H., Gilbert, D., Kennett, J., et al. (2024) · Wellcome Open Research · doi:10.12688/wellcomeopenres.23033.1 · Cited by 6
Impaired fear memory in a rat model of the brain-derived neurotrophic factor Val66Met polymorphism is reversed by chronic exercise
Jaehne, E. J., Antolasic, E. J., Creutzberg, K. C., Begni, V., Riva, M. A., & van den Buuse, M. (2023) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2023.107779 · Cited by 6
Mechanisms through which exercise reduces symptom severity and/or functional impairment in posttraumatic stress disorder (PTSD): Protocol for a living systematic review of human and non-human studies
Wright, S. L., Furukawa, T. A., Macleod, M. R., Ouma, S., Elugbadebo, O. O., Chiocchia, V., Friedrich, C., Ostinelli, E. G., Potts, J., Ramage, F. J., et al. (2023) · Wellcome Open Research · doi:10.12688/wellcomeopenres.19903.1 · Cited by 6
Exercise and health-related quality of life and work-related outcomes in primary care patients with anxiety disorders – A randomized controlled study
Wall, A., Henriksson, M., Nyberg, J., Holmgren, K. E., Isgaard, J., Lennartsson, A.-K., Svensson, J., Danielsson, L., Wærn, M., Åberg, M., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.05.092 · Cited by 8
Heart Rate Variability in Mental Health and Psychotherapy
Wendt, J., & Thayer, J. F. (2024) · Oxford University Press eBooks · doi:10.1093/oso/9780198888727.003.0004 · Cited by 6
The impact of exercise interventions on sleep in adult populations with depression, anxiety, or posttraumatic stress: review of the current evidence and future directions
Szuhany, K. L., Sullivan, A. J., Gills, J. L., & Kredlow, M. A. (2024) · Journal of Behavioral Medicine · doi:10.1007/s10865-024-00532-z · Cited by 8
A Review of PTSD Augmentation Strategies for Older Adults and Case of rTMS-Augmented Prolonged Exposure
Yasinski, C. W., Maples‐Keller, J. L., Trautner, H., Job, G. P., Rauch, S. A. M., McDonald, W. M., & ROTHBAUM, B. O. (2020) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2020.06.022 · Cited by 6
Augmenting PTSD treatment with physical activity: study protocol of the APPART study (Augmentation for PTSD with Physical Activity in a Randomized Trial)
Voorendonk, E. M., Sanches, S. A., Tollenaar, M. S., de Jongh, A., & van Minnen, A. (2022) · European Journal of Psychotraumatology · doi:10.1080/20008198.2021.2016219 · Cited by 6
Spreading the reduction of fear: A narrative review of generalization of extinction learning in human fear conditioning
Wong, A. H. K. (2025) · Clinical Psychology Review · doi:10.1016/j.cpr.2025.102580 · Cited by 6
Prolonged exposure therapy for PTSD among spinal cord injury survivors: Study protocol for a randomized controlled trial
Powers, M. B., Pogue, J. R., Curcio, N., Patel, S., Wierzchowski, A., Thomas, E. V., Warren, A. M., Adams, M., Turner, E. D., Carl, E., et al. (2021) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2021.100763 · Cited by 5
Exercise and Posttraumatic Stress Disorder
Rosenbaum, S., Stubbs, B., Schuch, F. B., & Vancampfort, D. (2017) · Springer eBooks · doi:10.1007/978-3-662-49322-9_16 · Cited by 5
Testing the efficacy of a brief exercise intervention for enhancing exposure therapy outcomes
Weisman, J. S., & Rodebaugh, T. L. (2020) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2020.102266 · Cited by 7
Flexibility in Treatment: A Trial of Walking Psychotherapy
Schen, C. R. (2020) · Psychodynamic Psychiatry · doi:10.1521/pdps.2020.48.3.295 · Cited by 5
Advances in the pharmacotherapeutic management of post-traumatic stress disorder
Akhtar, A., & Sah, S. P. (2021) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2021.1935871 · Cited by 5
L’exercice physique pour la santé mentale : mécanismes, recommandations, recherches futures
Legrand, F. D., Chaouloff, F., Ginoux, C., Ninot, G., Polidori, G., Beaumont, F., Murer, S., Jeandet, P., & Pélissolo, A. (2023) · L Encéphale · doi:10.1016/j.encep.2023.03.004 · Cited by 8
Sports, Stress, and Health
Gerber, M., & Colledge, F. (2023) · Springer eBooks · doi:10.1007/978-3-031-03921-8_27 · Cited by 5
The therapeutic potential of exercise in post-traumatic stress disorder and its underlying mechanisms: A living systematic review of human and non-human studies
Wright, S. L., Chiocchia, V., Elugbadebo, O. O., Ouma, S., Furukawa, T. A., Friedrich, C., Austin, C., Dehdarirad, H., Gilbert, D., Kennett, J., et al. (2025) · Wellcome Open Research · doi:10.12688/wellcomeopenres.23033.4 · Cited by 3
The increase in vagally-mediated heart rate variability mediates treatment effects of exercise on global symptom severity across diagnostically heterogenous mental disorders: A secondary analysis of the ImPuls trial
Zeibig, J., Takano, K., Seiffer, B., Sudeck, G., Rösel, I., Hautzinger, M., & Wolf, S. (2023) · Mental health and physical activity · doi:10.1016/j.mhpa.2023.100537 · Cited by 4
Sportliche Aktivität und psychische Erkrankungen
Wolf, S., Zeibig, J., Giel, K. E., Granz, H., Sudeck, G., & Thiel, A. (2020) · PPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie · doi:10.1055/a-1193-2584 · Cited by 7
Empirical status of mechanisms of change.
Vrijsen, J. N., de Kleine, R. A., Becker, E. S., Wenzel, A. E., & Smits, J. A. J. (2021) · American Psychological Association eBooks · doi:10.1037/0000218-004 · Cited by 5
Acute changes in affective valence and perceived distress predict reductions in PTSD symptom severity
Whitworth, J. W., SantaBarbara, N. J., Nosrat, S., Pebole, M. M., Cripe, B. G., & McKeon, G. (2023) · Mental health and physical activity · doi:10.1016/j.mhpa.2023.100523 · Cited by 3
Posttraumatic stress disorder increases thrombosis risk: Evidence from a biobank data set
Lau, H. C., Sinnott, S. M., Abohashem, S., Civieri, G., Aldosoky, W., Karam, K. A., Khalil, M., Qamar, I., Rosovsky, R. P. G., Osborne, M. T., et al. (2024) · American Journal of Hematology · doi:10.1002/ajh.27468 · Cited by 3
Effects of high intensity interval training on serum brain-derived neurotrophic factor in individuals with PTSD
Jäger, A., Pieper, A., Priebe, K., Hellweg, R., Meyer, K., Herrmann, S., Wolfarth, B., Grummt, M., Ströhle, A., & Schoofs, N. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.11.009 · Cited by 3
The therapeutic potential of exercise in post-traumatic stress disorder and its underlying mechanisms: A living systematic review of human and non-human studies
Wright, S. L., Chiocchia, V., Elugbadebo, O. O., Ouma, S., Furukawa, T. A., Friedrich, C., Austin, C., Dehdarirad, H., Gilbert, D., Kennett, J., et al. (2025) · Wellcome Open Research · doi:10.12688/wellcomeopenres.23033.2 · Cited by 3
Exercise for Mental Health: Current Perspectives, Clinical Practice Implications, and Future Directions
Carl, E., Mason, J. E., Smits, J. A. J., & Asmundson, G. J. G. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-818697-8.00074-1 · Cited by 3
Effect of Aerobic Exercises on Memory and Attention in Veterans with Post-Traumatic Stress Disorder
Moslehi, M., Shahbazi, M., Arabameri, E., & Boroujeni, S. T. (2019) · مجله طب جانباز · doi:10.29252/ijwph.11.3.117 · Cited by 3
Exercise and PTSD
Kinsman, L. M., Norrie, H. J., Rachor, G. S., & Asmundson, G. J. G. (2024) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2024_500 · Cited by 2
Augmentation of psychotherapy with exercise in adult populations affected by posttraumatic stress disorder: a systematic review of randomized controlled trials
Niemeyer, H., Opper, F., Sjöström, L. M., Knaevelsrud, C., & Nohr, L. (2025) · European Journal of Psychotraumatology · doi:10.1080/20008066.2025.2589025 · Cited by 3
Comorbid treatment of traumatic brain injury and mental health disorders
Ragsdale, K. A., Nichols, A., Mehta, M., Maples‐Keller, J. L., Yasinski, C. W., Hyatt, C. S., Watkins, L. E., Loucks, L. A., Carbone, E., Rauch, S. A. M., et al. (2024) · Neurorehabilitation · doi:10.3233/nre-230235 · Cited by 2
Delivering trauma-focused physiotherapy interventions for trauma-exposed refugees: a qualitative study exploring perspectives and experiences from Jordan and Kenya
Khalil, H., Fricker, I., Nazzal, M. S., Al-Qudah, A., Lababneh, T., Yousef, H., Golden, S., & Busse, M. E. (2025) · Physiotherapy Theory and Practice · doi:10.1080/09593985.2025.2484609 · Cited by 2
Physical activity and exercise for the prevention and management of anxiety
Schuch, F. B., Stubbs, B., & Kandola, A. A. (2021) · Society for Transparency, Openness, and Replication in Kinesiology eBooks · doi:10.51224/b1016 · Cited by 2
Changes in affect, physical activity, physical health, and sleep in cognitive behavioral therapy for anxiety: A pilot study
Brown, L. A., Narine, K., Asnaani, A., Bredemeier, K., & Mu, W. (2022) · Journal of Behavioral and Cognitive Therapy · doi:10.1016/j.jbct.2021.12.006 · Cited by 2
Adjuvante Therapie bei posttraumatischer Belastungsstörung
Schanz, C. G., Equit, M., & Michael, T. (2019) · PiD - Psychotherapie im Dialog · doi:10.1055/a-0771-5138 · Cited by 2
Cardiorespiratory fitness as protection against the development of memory intrusions: A prospective trauma analogue study
Voorendonk, E. M., Meyer, T., Duken, S. B., & van Ast, V. A. (2021) · Biological Psychology · doi:10.1016/j.biopsycho.2021.108189 · Cited by 2
Behandlung der PTBS bei Erwachsenen
Augsburger, M., Bering, R., Böttche, M., Ehring, T. W., Frommberger, U., Gast, U., Hecker, T., Hoffmann, A., Kleim, B., Knaevelsrud, C., et al. (2019) · Springer eBooks · doi:10.1007/978-3-662-59783-5_2 · Cited by 1
The effects of pre-extinction stress vs. physical exercise on contextual retrieval and generalization
Wolsink, L. N., Wolf, O. T., Merz, C. J., & Jentsch, V. L. (2026) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2026.107793 · Cited by 1
Effects of Aerobic Exercise on Patients with Mental Illness in a Veterans Inpatient Psychiatric Unit: A Review of the Literature
McCash, J. A., & Abraham, S. (2017) · International Journal of Studies in Nursing · doi:10.20849/ijsn.v3i1.235 · Cited by 1
Sportliche Aktivität und psychische Erkrankungen
Wolf, S., Zeibig, J., Giel, K. E., Granz, H., Sudeck, G., & Thiel, A. (2020) · PSYCH up2date · doi:10.1055/a-0973-1982 · Cited by 1
Impact of Stress and Exercise on Fear Extinction
Provencher, J., Cernik, R., & Marin, M. (2023) · Current topics in behavioral neurosciences · doi:10.1007/7854_2023_432 · Cited by 1
Moderate-intensity aerobic exercise training as an adjunct to trauma-focused psychotherapy in traumatized refugees and asylum seekers: study protocol of a randomized controlled trial
Lüder, C. C., Michael, T., Lass‐Hennemann, J., Schanz, C. G., Venhorst, A., Meyer, T., & Equit, M. (2023) · European Journal of Psychotraumatology · doi:10.1080/20008066.2023.2251777 · Cited by 1
Pharmacological, Somatic, and Behavioral Augmentations of PE
Bird, C. M., Douglas, M. E., & Powers, M. B. (2024) · CBT: science into practice · doi:10.1007/978-3-031-72720-7_11 · Cited by 1
The therapeutic potential of exercise in post-traumatic stress disorder and its underlying mechanisms: A living systematic review of human and non-human studies
Wright, S. L., Chiocchia, V., Elugbadebo, O. O., Ouma, S., Furukawa, T. A., Friedrich, C., Austin, C., Dehdarirad, H., Gilbert, D., Kennett, J., et al. (2025) · Wellcome Open Research · doi:10.12688/wellcomeopenres.23033.3
Mechanisms through which exercise reduces symptom severity and/or functional impairment in posttraumatic stress disorder (PTSD): Protocol for a living systematic review of human and non-human studies
Wright, S. L., Furukawa, T. A., Macleod, M. R., Ouma, S., Elugbadebo, O. O., Chiocchia, V., Friedrich, C., Ostinelli, E. G., Potts, J., Ramage, F. J., et al. (2025) · Wellcome Open Research · doi:10.12688/wellcomeopenres.19903.3 · Cited by 1
Symptômes dissociatifs et conduites à risques dans un cas de trouble de stress post-traumatique (TSPT) comorbide d’un trouble lié à l’usage de substances (TUS)
Tapia, G., Marquebieille, C., Delile, J., Othily, E., & Perez-Dandieu, B. (2017) · European Journal of Trauma & Dissociation · doi:10.1016/j.ejtd.2017.07.001 · Cited by 1
Exploring Resistance Training as a Potential Standalone Treatment for Anxious Adults Who Screen Positive for Posttraumatic Stress Disorder
Whitworth, J. W. (2018) · doi:10.7916/d8544510 · Cited by 1
Exercise and Posttraumatic Stress Disorder
Rosenbaum, S., Stubbs, B., Schuch, F. B., & Vancampfort, D. (2017) · Springer eBooks · doi:10.1007/978-3-662-49411-0_16-1 · Cited by 3
To Examine the Effects of Exercise & Instructional Based Interventions on Executive Functioning, Motor Learning & Emotional Intelligence Abilities Among Older Adults
Rajeshkumar, L. (2021) · doi:10.37099/mtu.dc.etdr/1161 · Cited by 1
Brain derived neurotrophic factor mediated learning, fear acquisition and extinction as targets for developing novel treatments for anxiety
Oliveira, K. S., Hounie, A. G., Cappi, C., & Diniz, J. B. (2016) · Jornal Brasileiro de Psiquiatria · doi:10.1590/0047-2085000000132 · Cited by 1
Exploratory Analysis Of PTSD Severity And Objective Measures Of Physical Activity Among Combat Veterans
Sauceda, D. O. (2016) · Scholar Commons (University of South Carolina)
The Efficacy of Aerobic Exercise and Resistance Training for Anxiety-Related Disorders and Constructs: A Randomized Controlled Trial
LeBouthillier, D. M. (2016) · doi:10.17605/osf.io/dj3ba
The Effect of Physical Activity on Post-Traumatic Stress Disorder Among Parents of Pediatric Cancer Survivors
Huot, V., & Fitzpatrick, T. R. (2018) · Springer eBooks · doi:10.1007/978-3-319-75223-5_9 · Cited by 1
Investigating Exercise for Anxiety and Depression Treatment: A Case Report
McKeon, G., Chen, A., & Rosenbaum, S. (2019) · Journal of Clinical Exercise Physiology · doi:10.31189/2165-6193-8.3.115
Voluntary Chronic Exercise Decreases Nociceptive Responses Before and After a Traumatic Stressor
Ford, S. J., Baiamonte, B. A., Hollander, D. B., & Kraemer, R. R. (2019) · Journal of Biology and Life Science · doi:10.5296/jbls.v11i1.15396
Correction to: Effects of Moderate Treadmill Exercise and Fluoxetine on Spatial Memory and Serum BDNF Levels in an Animal Model of Post-traumatic Stress Disorder
Shafia, S., Vafaei, A. A., & Rashidy‐Pour, A. (2019) · Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Māzandarān/Journal of Mazandaran University of Medical Sciences
Deepening extinction in a virtual reality treatment for fear of heights
McInerney, J. (2019)
Veterans suffering from post-traumatic stress disorder – literature analyzing: symptoms, statistics and therapies
Kozyra, M., Zimnicki, P., Kaczerska, J., Śmiech, N., Nowińska, M., & Milanowska, J. (2020) · Journal of Education Health and Sport · doi:10.12775/jehs.2020.10.08.005
Associations between physical activity and posttraumatic stress disorder: a systematic review and daily diary study
Graham, R. (2020) · UVic’s Research and Learning Repository (University of Victoria)
MOVING ON FROM TRAUMA: AEROBIC EXERCISE IN THE TREATMENT OF PTSD
Webb, S. (2020) · Digital Collections of Colorado (Colorado State University)
Depression with auto-aggressive manifestations in victims during a radiation disaster and fighting
Otroshchenko, N., & Otroshchenko, P. (2020) · Radiation Diagnostics Radiation Therapy · doi:10.37336/2707-0700-2020-4-3
Abstract: Exercise for Mental Health: Current Perspectives, Clinical Practice Implications, and Future Directions
Carl, E. (2021) · doi:10.26153/tsw/12135
Pediatric Obsessive-Compulsive Disorder
Guzick, A. G., Schneider, S. C., & Storch, E. A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818697-8.00028-5
Sportliche Aktivität und psychische Erkrankungen
Wolf, S., Zeibig, J., Giel, K. E., Granz, H., Sudeck, G., & Thiel, A. (2021) · Physikalische Medizin Rehabilitationsmedizin Kurortmedizin · doi:10.1055/a-1529-0831
Einsatz adjuvanter Therapien zur Behandlung der Posttraumatischen Belastungsstörung
Equit, M., Schanz, C. G., Kotzur, M., & Michael, T. (2022) · PTT - Persönlichkeitsstörungen: Theorie und Therapie · doi:10.21706/ptt-26-1-42
References
(2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804051-5.00032-9
The value of exercise physiology services delivered from a university health clinic
Mullins, R. W. (2022) · Queensland University of Technology · doi:10.5204/thesis.eprints.231915
Körperliche Aktivität bei spezifischen psychischen Erkrankungen
Bendau, A., Petzold, M. B., & Ströhle, A. (2023) · Springer eBooks · doi:10.1007/978-3-662-66208-3_12
Einsatzmöglichkeiten körperlicher Aktivität in der Behandlung psychischer Erkrankungen
Bendau, A., Petzold, M. B., & Ströhle, A. (2023) · Springer eBooks · doi:10.1007/978-3-662-66208-3_11
Longitudinal Links between PTSD and Physical Activity in 9/11 World Trade Center First Responders
Shteynberg, Y. A. (2024) · University of North Texas Digital Library (University of North Texas) · doi:10.12794/metadc2356127
Mechanisms through which exercise reduces symptom severity and/or functional impairment in posttraumatic stress disorder (PTSD): Protocol for a living systematic review of human and non-human studies
Wright, S. L., Furukawa, T. A., Macleod, M. R., Ouma, S., Elugbadebo, O. O., Chiocchia, V., Friedrich, C., Ostinelli, E. G., Potts, J., Ramage, F., et al. (2025) · Wellcome Open Research · doi:10.12688/wellcomeopenres.19903.2
Augmentation of trauma-focused psychotherapy for post-traumatic stress disorder: a protocol for a systematic review and meta-analysis
Mewes, L., Langhammer, T., Torbecke, J., Fendel, J. C., & Lueken, U. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-090571 · Cited by 1
Additional file 1 of Efficacy and cost-effectiveness of a Transdiagnostic group-based exercise intervention: study protocol for a pragmatic multi-site randomized controlled trial
Wolf, S., Seiffer, B., Zeibig, J.-M., Welkerling, J., Bauer, L. L., Frei, A. K., Studnitz, T., Rosenstiel, S., Fiedler, D. V., Helmhold, F., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16909996
Activités physiques et trouble de stress post-traumatique
Martin‐Krumm, C., Eymond, D., & Trousselard, M. (2025) · Elsevier eBooks · doi:10.1016/b978-2-294-78847-5.00008-7
The role of exercise in post-traumatic stress disorder: clinical evidence, sleep, cognition, and psychotherapy augmentation
Li, Y., & 李书义 (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1889239
Sport- und Bewegungstherapie bei Posttraumatischen Belastungsstörungen
Köllner, V., Kleinschmidt, J., & Michael, T. (2026) · PiD - Psychotherapie im Dialog · doi:10.1055/a-2720-1782
Investigation of the effects of two exercise protocols on behavioral and biochemical changes in ovariectomized rats exposed to single prolonged stress
Amiri, A., Shoshtari, A., Janbazi, M., Seyedpour, S. P., Jamali, S. R., Shafia, S., & Akhoundzadeh, K. (2026) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2026.09.003
Exercise Interventions for PTSD: A Systematic Review and Network Meta-Analysis of Overall Effects, Comparative Effectiveness, and Ranking Uncertainty
Eun, H.-B., & Yoo, S. K. (2026) · Healthcare · doi:10.3390/healthcare14193166

Authors: Powers, M. B., Medina, J. L., Burns, S., Kauffman, B. Y., Monfils, M., Asmundson, G. J. G., Diamond, A., McIntyre, C., & Smits, J. A. J.
Affiliations: The University of Texas at Austin (US)
University of Regina (CA)
The University of Texas at Dallas (US)
Corresponding author: Powers, Mark B.
ORCID: Powers, Mark B.
Medina, Johnna L.
Monfils, Marie
Asmundson, Gordon J.G.
McIntyre, Christa
Smits, Jasper A.J.
Venue: Cognitive Behaviour Therapy
Publisher: Informa UK Limited
Published: 2015-02-23
Volume: 44
Issue: 4
Pages: 314-327
ISSN: 1650-6073 (ISSN-L)
1651-2316
DOI: 10.1080/16506073.2015.1012740
PMC: PMC4464974
OpenAlex: W1987008872
Cited by: 194
References: 120
Citations by year: 2026: 5 · 2025: 11 · 2024: 19 · 2023: 23 · 2022: 20 · 2021: 24 · 2020: 23 · 2019: 23 · 2018: 17 · 2017: 15 · 2016: 6 · 2015: 8
FWCI: 19.04
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Cognitive Behaviour Therapy (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Radboud Repository (Radboud University) (submittedVersion)
Funders: National Institutes of Health (5r01da027533-04)
National Institute of Mental Health (R15MH099655, R01MH091147)
National Institute on Drug Abuse (R01-DA027533, F31DA036919, K01DA035930)
Topics: Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Keywords: post-traumatic stress disorder, prolonged exposure therapy, physical activity, brain-derived neurotrophic factor, fear extinction, treadmill exercise, anxiety disorders, synaptic plasticity
MeSH terms: Adult, Combined Modality Therapy, Exercise Therapy, Female, Humans, Implosive Therapy, Male, Pilot Projects, Stress Disorders, Post-Traumatic, Exercise, Brain-Derived Neurotrophic Factor, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Exercise Augmentation of Exposure Therapy for PTSD: Rationale and Pilot Efficacy Data

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks