The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Characterization of the size, shape, and state of dispersion of nanoparticles for toxicological studies
Abstract
This paper describes the issues relating to the measurement of nanoparticle size, shape and dispersion when evaluating the toxicity of nanoparticles. Complete characterization of these materials includes much more than size, size distribution and shape; nonetheless, these attributes are usually the essential foundation. The measurement of particle size, particularly at scales of 100 nm or less, can be challenging under the best of conditions. Measurements that are routine in the laboratory setting become even more difficult when made under the physiological conditions relevant to toxicity studies, where the environment of the particles can be quite complex. Passive and active cellular responses, as well as the presence of a variety of nano-scale biological structures, often complicate the collection and interpretation of size and shape data. In this paper, we highlight several of the common issues faced when characterizing nanoparticles for toxicity testing and suggest general protocols to address these problems.
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Citations
Cites
Mechanisms in the Pathogenesis of Asbestosis and Silicosis
MOSSMAN, B. T., & CHURG, A. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.157.5.9707141 · Cited by 971
Heyder, J. (2004) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200409-046ta · Cited by 601 · cited 2×
“For example, well established models have been developed for predicting where in the lung particulates of a given aerodynamic diameter are deposited (ICRP 1994; Heyder 2004; Zhang et al. 2005); (b) Size is a factor in the ability of the body to clear foreign particles (Renwick et al.”
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Cited by
Jiang, J., Oberdörster, G., & Biswas, P. (2009) · Journal of Nanoparticle Research · doi:10.1007/s11051-008-9446-4 · Cited by 1,713
Sharifi, S., Behzadi, S., Laurent, S., Laird Forrest, M., Stroeve, P., & Mahmoudi, M. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15188f · Cited by 1,460
Duan, X., & Li, Y. (2013) · Small · doi:10.1002/smll.201201390 · Cited by 926
Yusuf, A., Almotairy, A. R. Z., Henidi, H., Alshehri, O. Y., & Aldughaim, M. S. (2023) · Polymers · doi:10.3390/polym15071596 · Cited by 914
Sapsford, K. E., Tyner, K. M., Dair, B. J., Deschamps, J. R., & Medintz, I. L. (2011) · Analytical Chemistry · doi:10.1021/ac200853a · Cited by 538
Metadata
- Authors
- Powers, K. W., Palazuelos, M., Moudgil, B. M., & Roberts, S. M.
- Venue
- Nanotoxicology
- Publisher
- Informa UK Limited
- Published
- 2007-01
- Volume
- 1
- Issue
- 1
- Pages
- 42-51
- ISSN
- 1743-5390 (ISSN-L)
- 1743-5404
- OpenAlex
- W2004010748
- Cited by
- 383
- References
- 2
- FWCI
- 10.42
- Type
- journal article
- Language
- en
- Open access
- closed
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- Powers, K. W., Palazuelos, M., Moudgil, B. M., & Roberts, S. M. (2007). Characterization of the size, shape, and state of dispersion of nanoparticles for toxicological studies. Nanotoxicology. https://doi.org/10.1080/17435390701314902
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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