The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Improved method to disperse nanoparticles for in vitro and in vivo investigation of toxicity
Abstract
Nanoparticles agglomerate and clump in solution, making it difficult to accurately deliver them for in vivo or in vitro experiments. Thus, experiments were conducted to determine the best method to suspend nanosized particles. Ultrafine and fine carbon black and titanium dioxide were suspended in phosphate buffered saline (PBS), rat and mouse bronchoalveolar lavage fluid (BALF), and PBS containing dipalmitoyl phosphatidylcholine (DPPC) and/or mouse serum albumin. To assess and compare how these various suspension media dispersed the nanoparticles, images were taken using light microscopy, scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The results of this study show that PBS is not a satisfactory medium to prepare nanoparticle suspensions. However, BALF was an excellent media in which to suspend nanoparticles. The use of PBS containing protein or DPPC alone, in concentrations found in BALF, did not result in satisfactory particle dispersion. However, PBS-containing protein plus DPPC was satisfactory, although less effective than BALF.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Donaldson, K., Aitken, R., Tran, L., Stone, V., Duffin, R., Forrest, G., & Alexander, A. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfj130 · Cited by 1,167
Porter, D. W., Barger, M., Robinson, V. A., Leonard, S. S., Landsittel, D., & Castranova, V. (2002) · Toxicology · doi:10.1016/s0300-483x(02)00061-6 · Cited by 46
Self-citation
Cited by
Understanding biophysicochemical interactions at the nano–bio interface
Nel, A. E., Mädler, L., Velegol, D., Xia, T., Hoek, E. M. V., Somasundaran, P., Klaessig, F., Castranova, V., & Thompson, M. (2009) · Nature Materials · doi:10.1038/nmat2442 · Cited by 7,083
Self-citationJiang, J., Oberdörster, G., & Biswas, P. (2009) · Journal of Nanoparticle Research · doi:10.1007/s11051-008-9446-4 · Cited by 1,713
Sharifi, S., Behzadi, S., Laurent, S., Laird Forrest, M., Stroeve, P., & Mahmoudi, M. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15188f · Cited by 1,460
Stability and Aggregation of Metal Oxide Nanoparticles in Natural Aqueous Matrices
Keller, A. A., Wang, H., Zhou, D., Lenihan, H. S., Cherr, G., Cardinale, B. J., Miller, R., & Ji, Z. (2010) · Environmental Science & Technology · doi:10.1021/es902987d · Cited by 1,369
Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle
Saptarshi, S. R., Duschl, A., & Lopata, A. L. (2013) · Journal of Nanobiotechnology · doi:10.1186/1477-3155-11-26 · Cited by 1,079
Metadata
- Authors
- Sager, T. M., Porter, D. W., Robinson, V. A., Lindsley, W. G., Schwegler-Berry, D. E., & Castranova, V.
- Venue
- Nanotoxicology
- Publisher
- Informa UK Limited
- Published
- 2007-01
- Volume
- 1
- Issue
- 2
- Pages
- 118-129
- ISSN
- 1743-5390 (ISSN-L)
- 1743-5404
- OpenAlex
- W1977529440
- Cited by
- 244
- References
- 2
- FWCI
- 11.15
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Improved method to disperse nanoparticles for in vitro and in vivo investigation of toxicity. https://app.cochat.ai/papers/10.1080/17435390701381596
- The paper
- Sager, T. M., Porter, D. W., Robinson, V. A., Lindsley, W. G., Schwegler-Berry, D. E., & Castranova, V. (2007). Improved method to disperse nanoparticles for in vitro and in vivo investigation of toxicity. Nanotoxicology. https://doi.org/10.1080/17435390701381596
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
