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How does yoga reduce stress? A systematic review of mechanisms of change and guide to future inquiry
Abstract
Yoga is increasingly used in clinical settings for a variety of mental and physical health issues, particularly stress-related illnesses and concerns, and has demonstrated promising efficacy. Yet the ways in which yoga reduces stress remain poorly understood. To examine the empirical evidence regarding the mechanisms through which yoga reduces stress, we conducted a systematic review of the literature, including any yoga intervention that measured stress as a primary dependent variable and tested a mechanism of the relationship with mediation. Our electronic database search yielded 926 abstracts, of which 71 were chosen for further inspection and 5 were selected for the final systematic review. These five studies examined three psychological mechanisms (positive affect, mindfulness and self-compassion) and four biological mechanisms (posterior hypothalamus, interleukin-6, C-reactive protein and cortisol). Positive affect, self-compassion, inhibition of the posterior hypothalamus and salivary cortisol were all shown to mediate the relationship between yoga and stress. It is striking that the literature describing potential mechanisms is growing rapidly, yet only seven mechanisms have been empirically examined; more research is necessary. Also, future research ought to include more rigorous methodology, including sufficient power, study randomisation and appropriate control groups.
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From Embodied Cognition in Meditation, Yoga, and Ethics—An Experimental Single-Case Study on the Differential Effects of Four Mind–Body Treatments (2022) · cites this paper as [25]
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“To date, surprisingly few studies have focused on identifying the mechanisms through which yoga reduces stress (Riley & Park, 2015), and of those, most lacked adequate sample sizes, time frames and theoretical bases.”
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“Many clinical studies on yoga as medical science have been published in the topranking journals of various medical fields, such as cardiology for cardiovascular diseases [8–10], coronary heart disease [11], hypertension [12], atrial fibrillation and arrhythmia [13] and vasovagal syncope [14]; internal medicine for met…”
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BackgroundStress, mindfulness, and the allergic patient
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“more physical components of yoga can have their own stress management capabilities [86].”
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Carlson, L. E., Toivonen, K., & Subnis, U. B. (2019) · The Cancer Journal · doi:10.1097/ppo.0000000000000395 · Cited by 32
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“47 There is increasing interest in the potential role of yoga as an intervention for mental health concerns.”
Taking a Stand for Office-Based Workers' Mental Health: The Return of the Microbreak
Mainsbridge, C. P., Cooley, D., Dawkins, S., de Salas, K., Tong, J. S., Schmidt, M. W., & Pedersen, S. (2020) · Frontiers in Public Health · doi:10.3389/fpubh.2020.00215 · Cited by 29
“Conversely, an inability to maintain the ideal mood state has been associated with stress (22, 23) and adverse health symptomology (24, 25).”
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“Mindfulness, or the state of being keenly aware of the present, has been shown to increase following yoga practice and leads to decreased perceived stress [7].”
BackgroundInfluentialThe Effect of Yoga on Cardiovascular Disease Risk Factors: A Meta-Analysis
Isath, A. M., Kanwal, A. S., Virk, H. U. H., Bandyopadhyay, D., Wang, Z., Kumar, A., Kalra, A., Naidu, S. S., Lavie, C. J., Virani, S. S., et al. (2023) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2023.101593 · Cited by 26
Kuppusamy, M., Dilara, K., Ravishankar, P., Julius, A., Padmavathi, R., Poonguzhali, S., & Vijayakumar, V. (2021) · EXPLORE · doi:10.1016/j.explore.2021.07.005 · Cited by 25
de Witte, M., Kooijmans, R., Hermanns, M., van Hooren, S., Biesmans, K., Hermsen, M. A., Stams, G. J. J. M., & Moonen, X. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.742566 · Cited by 31
“Stress is defined by Aldwin (2007) as the quality of an experience produced by a person-environment transaction that, through either overarousal or underarousal, results in psychological or physiological distress (Aldwin, 2007; Riley and Park, 2015).”
BackgroundBrandão, T., Martins, I., Torres, A., & Remondes‐Costa, S. (2024) · Journal of Health Psychology · doi:10.1177/13591053231220710 · Cited by 24
“Indeed, self-compassion has been found to be a mechanism of change in Yoga interventions since it is a quality that results from contemplative practices (Riley and Park, 2015).”
BackgroundCampelo, G., de Araújo, J. R., Aristizabal, J. P., de Souza, W. C., & de Castilho, G. M. (2025) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-025-04825-x · Cited by 28
Effect of a single session of yoga and meditation on stress reactivity: A systematic review
Mandlik, G. V., Siopis, G., Nguyen, B., Ding, D., & Edwards, K. M. (2023) · Stress and Health · doi:10.1002/smi.3324 · Cited by 23
van der Meulen, R. T., Valentin, S., Bögels, S. M., & de Bruin, E. I. (2020) · Mindfulness · doi:10.1007/s12671-020-01557-6 · Cited by 29
Qi, X., Tong, J. S., Chen, S., He, Z., & Zhu, X. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.560152 · Cited by 22
“Participants performed 80 min of Hatha yoga exercise (Riley and Park, 2015) in a morning yoga class per week for 12 weeks.”
MethodStec, K., Kruszewski, M., & Ciechanowski, L. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20042845 · Cited by 22
“The system of yoga, itself over five thousand years old [2–5], forms an important part of such a holistic and integrated approach to human health, stress reduction [6], and physical culture.”
BackgroundResultYoga Research a Scientometric Assessment of Global Publications Output during 2007-16
Gupta, B., Ahmed, K. M., Dhawan, S., & Gupta, R. (2018) · Pharmacognosy Journal · doi:10.5530/pj.2018.3.65 · Cited by 23
Perceived benefits and barriers to yoga participation after stroke: A focus group approach
Harris, A., Austin, M., Blake, T. M., & Bird, M. (2018) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2018.11.015 · Cited by 22
Stan, R. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.792642 · Cited by 34
“A mindfulness approach combined with releasing eye strain has proven to provide an adaptive response to stressors (Riley and Park, 2015).”
BackgroundEllis, D. A., Carcone, A. I., Slatcher, R. B., & Sibinga, E. M. S. (2017) · Health Psychology and Behavioral Medicine · doi:10.1080/21642850.2017.1415810 · Cited by 21
“Recent reviews (Baer, 2010; Riley & Park, 2015; Tang, Hölzel, & Posner, 2015; Witkiewitz et al., 2014) suggest that mindfulness practices may not only improve stress tolerance and emotion regulation but that they may also improve focus and attention regulation, resulting in fewer overlearned (and…”
BackgroundNejadghaderi, S. A., Mousavi, S. E., Fazlollahi, A., Asghari, K. M., & Garfin, D. R. (2024) · Psychiatry Research · doi:10.1016/j.psychres.2024.116098 · Cited by 27
“Yoga may help address PTSD symptoms by improving emotion and sympathetic nervous system regulation, reducing hyperarousal and enhancing vagal activity, a key component of the parasympathetic nervous system (Kamraju, 2023; Riley and Park, 2015).”
For Body and Mind: Practicing Yoga and Emotion Regulation
Kobylińska, D., Lewczuk, K., Marchlewska, M., & Pietraszek, A. (2018) · Social Psychological Bulletin · doi:10.5964/spb.v13i1.25502 · Cited by 23
“Similarly, in a review by Riley and Park (2015), yoga interventions were also described as effective in reducing stress.”
BackgroundMetri, K., Raghuram, N., Narayan, M., Sravan, K., Sekar, S., Bhargav, H., Babu, N., Mohanty, S., & Revankar, R. R. (2023) · Work · doi:10.3233/wor-210269 · Cited by 20
Csala, B., Ferentzi, E., Tihanyi, B. T., Drew, R., & Köteles, F. G. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.01375 · Cited by 20
Matko, K., Sedlmeier, P., & Bringmann, H. C. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph191811734 · Cited by 21
Stress management interventions for adults with heart failure: Systematic review and meta-analysis.
Gathright, E. C., Salmoirago‐Blotcher, E., DeCosta, J., Donahue, M. L., Feulner, M. M., Cruess, D. G., Wing, R. R., Carey, M. P., & Scott‐Sheldon, L. A. J. (2021) · Health Psychology · doi:10.1037/hea0001084 · Cited by 21
Dyer, N. L., Borden, S., Dusek, J. A., & Khalsa, S. B. S. (2020) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2020.102470 · Cited by 21
Yoga and nonsuicidal self-injury: Mediational effects of self-compassion and body appreciation
Muehlenkamp, J. J., & Wagner, E. M. (2022) · Body Image · doi:10.1016/j.bodyim.2022.08.001 · Cited by 18
Heuel, L., Otto, A.-K., & Wollesen, B. (2023) · German Journal of Exercise and Sport Research · doi:10.1007/s12662-023-00922-6 · Cited by 24
“One might argue that yoga has the potential to improve biochemical markers of stress (Riley & Park, 2015); however, Mandal et al. (2021) did not find improvements in biochemical outcomes after a 20-h yoga intervention.”
Kalra, S., Miraj, M., Ajmera, P., Shaik, R. A., Seyam, M. K., Shawky, G. M., Alasiry, S. M., Mohamed, E. S. H., Alasiri, H., Alzhrani, M., et al. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.942740 · Cited by 17
“Various reported benefits of yoga include reduction in blood pressure, enhanced dominance of the parasympathetic nervous system over the sympathetic nervous system, normalization of endocrinal function and gastrointestinal function, improved musculoskeletal fitness and posture, enhanced energy levels, normalization of…”
BackgroundHolistic frailty prevention: The promise of movement‐based mind–body therapies
Loewenthal, J., Berning, M. J., Wayne, P. M., Eckstrom, E., & Orkaby, A. R. (2023) · Aging Cell · doi:10.1111/acel.13986 · Cited by 19
“In addition, yoga modulates the hypothalamic– pituitary– adrenal axis (HPA), reducing markers such as cortisol, catecholamines, and renin– angiotensin (Purdy, 2013; Riley & Park, 2015).”
BackgroundYoga as an Adjunctive Intervention to Medication-Assisted Treatment with Buprenorphine+Naloxone
Lander, L. R., Chiasson-Downs, K., Andrew, M. E., Rader, G., Dohar, S., & Waibogha, K. (2017) · Journal of Addiction Research & Therapy · doi:10.4172/2155-6105.1000354 · Cited by 17
Brems, C. (2020) · Springer eBooks · doi:10.1007/978-3-030-30892-6_10 · Cited by 17
Cartwright, T., Cahill, M., & Sadana, V. (2020) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2020.102339 · Cited by 17
Ma, Y., & Mumtaz, S. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1678367 · Cited by 48
“A 9-month study of yoga practitioners showed a 40% decrease in emotional reactivity to stressors, compared to only 15% in conventional exercisers (66).”
Acute Cortisol Profile Associations With Cognitive Impairment After Severe Traumatic Brain Injury
Barton, D. J., Kumar, R. G., Schuster, A. A., Juengst, S. B., Oh, B., & Wagner, A. K. (2021) · Neurorehabilitation and neural repair · doi:10.1177/15459683211048771 · Cited by 16
Gandolfi, M. G., Zamparini, F., Spinelli, A., & Prati, C. (2023) · Journal of Functional Morphology and Kinesiology · doi:10.3390/jfmk9010006 · Cited by 18
“…[31,32], irritable bowel [33], inflammatory markers [34,35] and immune system [36]; in neurology/psychology for stress, anxiety and burnout [37,38]; in pneumology [39,40]; in orthopedics/physiatry for chronic pain and pain-associated disorders [41–52] and disc herniation [45–47]; in…”
BackgroundTrent, N. L., Borden, S., Miraglia, M., Pasalis, E., Dusek, J. A., & Khalsa, S. B. S. (2019) · Global Advances in Health and Medicine · doi:10.1177/2164956119856856 · Cited by 19
Nirwan, M., Halder, K., Saha, M., Pathak, A., Balakrishnan, R., & Ganju, L. (2020) · Journal of Complementary and Integrative Medicine · doi:10.1515/jcim-2019-0240 · Cited by 17
Metadata
- Authors
- Riley, K. E., & Park, C. L.
- Affiliations
- University of Connecticut (US)
- Corresponding author
- Riley, Kristen E.
- Venue
- Health Psychology Review
- Publisher
- Informa UK Limited
- Published
- 2015-04-15
- Volume
- 9
- Issue
- 3
- Pages
- 379-396
- ISSN
- 1743-7199 (ISSN-L)
- 1743-7202
- OpenAlex
- W1971363556
- Cited by
- 287
- References
- 65
- Citations by year
- 2026: 26 · 2025: 36 · 2024: 38 · 2023: 31 · 2022: 24 · 2021: 39 · 2020: 31 · 2019: 15 · 2018: 18 · 2017: 18 · 2016: 8 · 2015: 3
- FWCI
- 2.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Health Psychology Review (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Keywords
- yoga, stress reduction, mechanisms of change, mediation, positive affect, mindfulness, self-compassion, posterior hypothalamus, interleukin-6, C-reactive protein, salivary cortisol, stress-related disorders
- MeSH terms
- C-Reactive Protein, Humans, Hydrocortisone, Stress, Psychological, Yoga, Interleukin-6, Treatment Outcome, Meditation
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