Cited by 11Sperm and Testicular FunctionUrologic and reproductive health conditionsMale Reproductive Health Studies

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The Relevance of Neutral α-Glucosidase Activity in Andrology

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Levrant, Seth, Watanabe, Marisela, Land, Spencer, Sauer, Ruben, Jeyendran, Rajasingam S.·2009·Systems Biology in Reproductive Medicine

Abstract

To assess the usefulness of routine determination of neutral alpha-glucosidase (NAG) in andrology, 216 ejaculates were analyzed for NAG activity and semen quality. A correlation between NAG activity and semen volume and sperm concentration was determined; however, no correlation was observed between NAG activity and sperm motility or sperm morphology. The number of azoospermic ejaculates that had NAG activity below acceptable levels was significantly higher than the number of non-azoospermic ejaculates with similarly low NAG levels. Routine determination of NAG activity is not practical; however, when an epididymal pathology leading to a physiological or anatomical functional alteration is suspected, the determination of NAG activity is a valuable tool in the diagnosis, and would also aid in the prognosis.

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Metadata

Authors
Levrant, S., Watanabe, M., Land, S., Sauer, R., & Jeyendran, R. S.
Affiliations
  • Weiss Memorial Hospital (US)
  • Instituto Nacional de Perinatología (MX)
Corresponding author
Jeyendran, Rajasingam S.
Venue
Systems Biology in Reproductive Medicine
Published
2009-01
Volume
55
Issue
2-3
Pages
116-119
ISSN
  • 1939-6368 (ISSN-L)
  • 1939-6376
OpenAlex
W2083225274
Cited by
11
References
1
Citations by year
2024: 1 · 2022: 2 · 2021: 1 · 2020: 4 · 2017: 1 · 2015: 1 · 2013: 1
FWCI
0.00
Type
journal article
Language
en
Open access
Locations
  • Systems Biology in Reproductive Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
  • Health Sciences › Medicine › Urology › Urologic and reproductive health conditions
  • Health Sciences › Medicine › Urology › Male Reproductive Health Studies
Keywords
neutral alpha-glucosidase, semen quality, azoospermia, sperm motility, sperm morphology, sperm concentration, semen volume, prognosis
MeSH terms
alpha-Glucosidases, Fertility, Humans, Infertility, Male, Male, Prognosis

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