The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
The impact of the gut microbiota on the reproductive and metabolic endocrine system
Open accessAbstract
As the gut microbiota exerts various effects on the intestinal milieu which influences distant organs and pathways, it is considered to be a full-fledged endocrine organ. The microbiota plays a major role in the reproductive endocrine system throughout a woman's lifetime by interacting with estrogen, androgens, insulin, and other hormones. Imbalance of the gut microbiota composition can lead to several diseases and conditions, such as pregnancy complications, adverse pregnancy outcomes, polycystic ovary syndrome (PCOS), endometriosis, and cancer; however, research on the mechanisms is limited. More effort should be concentrated on exploring the potential causes and underlying the mechanisms of microbiota-hormone-mediated disease, and providing novel therapeutic and preventive strategies.As the gut microbiota exerts various effects on the intestinal milieu which influences distant organs and pathways, it is considered to be a full-fledged endocrine organ. The microbiota plays a major role in the reproductive endocrine system throughout a woman's lifetime by interacting with estrogen, androgens, insulin, and other hormones. Imbalance of the gut microbiota composition can lead to several diseases and conditions, such as pregnancy complications, adverse pregnancy outcomes, polycystic ovary syndrome (PCOS), endometriosis, and cancer; however, research on the mechanisms is limited. More effort should be concentrated on exploring the potential causes and underlying the mechanisms of microbiota-hormone-mediated disease, and providing novel therapeutic and preventive strategies.
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Cites
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Cited by
Varghese, S., Rao, S., Khattak, A., Zamir, F., & Chaari, A. (2024) · Nutrients · doi:10.3390/nu16213663 · Cited by 152
Giraud, C., Callac, N., Boulo, V., Lam, J.-S., Pham, D., Selmaoui-Folcher, N., & Wabete, N. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.886752 · Cited by 26
Zhang, H., Zheng, L., Li, C., Jing, J., Li, Z., Sun, S., Xue, T., Zhang, K., Xue, M., Cao, C., et al. (2023) · Journal of Ovarian Research · doi:10.1186/s13048-023-01227-w · Cited by 27
Do probiotic interventions improve female unexplained infertility? A critical commentary
Favaron, A., Turkgeldi, E., Elbadawi, M., Gaisford, S., Basit, A. W., & Orlu, M. (2024) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2023.103734 · Cited by 9
Metadata
- Authors
- Qi, X., Yun, C., Pang, Y., & Qiao, J.
- Venue
- Gut Microbes
- Publisher
- Informa UK Limited
- Published
- 2021-01
- Volume
- 13
- Issue
- 1
- Pages
- 1-21
- ISSN
- 1949-0976 (ISSN-L)
- 1949-0984
- OpenAlex
- W3137079137
- Cited by
- 554
- References
- 42
- FWCI
- 19.05
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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