Sinus tachycardia: don’t blame the whistle-blower
Abstract
Sinus tachycardia due to sympathetic activation may be the ultimate response to support cardiac output. Abrupt heart rate reduction in this condition may be deleterious as is illustrated by two cases. Both patients were referred in cardiogenic shock after inappropriate treatment with a beta-blocking agent, initiated as a symptomatic treatment of a sinus tachycardia.Thus even if beta-blocking agents provoked a paradigm shift in the understanding of heart failure and became a cornerstone of the treatment, therapy should be initiated with knowledge of the underlying condition.
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Ablation in POTS will only exacerbate the problem and may lead to hypotension or syncope.
“since ablation in POTS, will only exacerbate the problem and may lead to hypotension or syncope. 65”
From Inappropriate sinus tachycardia (2019) · cites this paper as [65]
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Inappropriate sinus tachycardia
Olshansky, B., & Sullivan, R. M. (2019) · EP Europace · doi:10.1093/europace/euy128 · Cited by 80 · see citing works
“It is important to determine if tachycardia is due to POTS or an overlap syndrome since ablation in POTS, will only exacerbate the problem and may lead to hypotension or syncope.(65) Many treatment recommendations for patients with IST have not been well tested.”
BackgroundConventional management of inappropriate sinus tachycardia
Olshansky, B., & Sullivan, R. M. (2015) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-015-0034-0 · Cited by 5 · see citing works
“Not uncommonly, β-blockers tend to be associated with other symptoms or issues, particularly if IST is misdiagnosed [18].”
Background
- Authors
- De Pauw, M., Tromp, F., & De Buyzere, M.
- Affiliations
- Dept. of Cardiology, Ghent University Hospital, Belgium.
- Ghent University Hospital (BE)
- Venue
- Acta Cardiologica
- Publisher
- Informa UK Limited
- Published
- 2013-06
- Volume
- 68
- Issue
- 3
- Pages
- 315-317
- ISSN
- 0373-7934 (ISSN-L)
- 0001-5385
- OpenAlex
- W141139445
- Cited by
- 2
- References
- 0
- Citations by year
- 2018: 1 · 2015: 1
- FWCI
- 0.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta cardiologica. Supplementum (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Physical Sciences › Engineering › Biomedical Engineering › Mechanical Circulatory Support Devices
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Keywords
- sinus tachycardia, sympathetic activation, cardiogenic shock, beta-blockers, heart failure, heart rate reduction, cardiac output, adverse drug reactions
- MeSH terms
- Acute Disease, Adrenergic beta-Antagonists, Anti-Arrhythmia Agents, Drug Therapy, Combination, Female, Follow-Up Studies, Heart Conduction System, Heart Failure, Humans, Middle Aged, Tachycardia, Sinus, Ventricular Function, Left, Young Adult, Phosphodiesterase 5 Inhibitors
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