The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
The yeast cell-wall salvage pathway
Abstract
The integrity of the cell wall depends on the synthesis and correct assembly of its individual components. Several environmental factors, such as temperature up-shift, treatments with mating factors or with specific cell wall-perturbing drugs, or genetic factors, such as inactivation of cell wall-related genes (for example FKS1 or GAS1) can impair construction of the cell wall. As the cell wall is essential for preserving the osmotic integrity of the cell, several responses are triggered in response to cell-wall damage. This review focuses on the activation of salvage pathways that guarantee cell survival through remodeling of the extracellular matrix. These researches have useful implication for the study of similar pathways in human fungal pathogens, and for the evaluation of the efficacy of new antifungal drugs.
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“Our functional analyses demonstrate that CHS3 is crucial during hyphal growth in the absence of Phr1p and support the notion that Chs3p is the major compensatory chitin synthase both in cell wall stress and HWS in fungi [21, 28, 47, 62, 63].”
From Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling (2016) · cites this paper as [62]
In the citing paper
“Our functional analyses demonstrate that CHS3 is crucial during hyphal growth in the absence of Phr1p and support the notion that Chs3p is the major compensatory chitin synthase both in cell wall stress and HWS in fungi [21, 28, 47, 62, 63].”
From Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling (2016) · cites this paper as [62]
Citations
Cites
MAP Kinase Pathways in the Yeast Saccharomyces cerevisiae
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Self-citationSpatial regulation of the exocyst complex by Rho1 GTPase
Guo, W., Tamanoi, F., & Novick, P. (2001) · Nature Cell Biology · doi:10.1038/35070029 · Cited by 349
The Yeast Cell Wall and Septum as Paradigms of Cell Growth and Morphogenesis
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Cited by
Sorted by citations
The Fungal Cell Wall: Structure, Biosynthesis, and Function
Gow, N. A. R., Latge, J.-P., & Munro, C. A. (2017) · Microbiology Spectrum · doi:10.1128/microbiolspec.funk-0035-2016 · Cited by 1,423
Denning, D. W. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14472-8 · Cited by 1,131
Dynamics of cell wall structure in Saccharomyces cerevisiae
Klis, F. M., Mol, P. C., Hellingwerf, K. J., & Brul, S. (2002) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2002.tb00613.x · Cited by 1,007
Candidiasis and Mechanisms of Antifungal Resistance
Bhattacharya, S., Sae-Tia, S., & Fries, B. C. (2020) · Antibiotics · doi:10.3390/antibiotics9060312 · Cited by 474
Architecture of the dynamic fungal cell wall
Gow, N. A. R., & Lenardon, M. D. (2023) · Nature Reviews Microbiology · doi:10.1038/s41579-022-00796-9 · Cited by 447
Metadata
- Authors
- Popolo, L., Gualtieri, T., & Ragni, E.
- Affiliations
- University of Milan (IT)
- Corresponding author
- Popolo, L.
- ORCID
- Venue
- Medical Mycology
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-01
- Volume
- 39
- Issue
- 1
- Pages
- 111-121
- ISSN
- 0268-1218 (ISSN-L)
- 1369-3786
- 1460-2709
- OpenAlex
- W2162102216
- Cited by
- 142
- References
- 51
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 5 · 2021: 6 · 2020: 7 · 2019: 5 · 2018: 4 · 2017: 3 · 2016: 4 · 2015: 3 · 2014: 6 · 2013: 2 · 2012: 7
- FWCI
- 2.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Medical Mycology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Infectious Diseases › Fungal Infections and Studies
- Keywords
- yeast cell wall, salvage pathway, cell wall damage, cell wall remodeling, extracellular matrix, FKS1, GAS1, mating factor, antifungal drug targets, fungal pathogens, Saccharomyces cerevisiae
- MeSH terms
- Cell Wall, Fungal Proteins, Fungi, Protein Kinase C, Signal Transduction, Calcineurin, MAP Kinase Signaling System
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