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Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells.
Open accessAbstract
Uvomorulin is a cell-adhesion molecule implicated in the compaction process of mouse preimplantation embryos and the aggregation of embryonal carcinoma cells. A rabbit antiserum against purified uvomorulin also reacts with epithelial cells of various adult tissues. In this study, we investigated the localization of uvomorulin on adult intestinal epithelial cells using electron microscopic analyses. Uvomorulin was shown to exhibit a highly restricted localization in the intermediate junctions of these cells. The results are discussed with respect to a possible adhesive function of uvomorulin on intestinal epithelial cells.
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Cited by
Stevenson, B. R., Siliciano, J. D., Mooseker, M. S., & Goodenough, D. A. (1986) · The Journal of cell biology · doi:10.1083/jcb.103.3.755 · Cited by 1,638
Mengaud, J., Ohayon, H., Gounon, P., Mège, R.-M., & Cossart, P. (1996) · Cell · doi:10.1016/s0092-8674(00)81070-3 · Cited by 870
Gumbiner, B., Stevenson, B., & Grimaldi, A. (1988) · The Journal of cell biology · doi:10.1083/jcb.107.4.1575 · Cited by 799
The Neural Cell Adhesion Molecule (NCAM) as a Regulator of Cell-Cell Interactions
Rutishauser, U., Acheson, A., Hall, A. K., Mann, D. M., & Sunshine, J. (1988) · Science · doi:10.1126/science.3281256 · Cited by 787
Itoh, M., Nagafuchi, A., Moroi, S., & Tsukita, S. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.138.1.181 · Cited by 677
Metadata
- Authors
- Boller, K., Vestweber, D., & Kemler, R.
- Venue
- The Journal of cell biology
- Publisher
- Rockefeller University Press
- Published
- 1985-01-01
- Volume
- 100
- Issue
- 1
- Pages
- 327-332
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2152790702
- Cited by
- 422
- References
- 0
- FWCI
- 9.03
- Type
- journal article
- Language
- en
- Open access
- green
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- Boller, K., Vestweber, D., & Kemler, R. (1985). Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells. The Journal of cell biology. https://doi.org/10.1083/jcb.100.1.327
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