The DOI matches its Crossref record.
Three-dimensional reconstruction of the 70S Escherichia coli ribosome in ice: the distribution of ribosomal RNA.
Open accessAbstract
A reconstruction, at 40 A, of the Escherichia coli ribosome imaged by cryo-electron microscopy, obtained from 303 projections by a single-particle method of reconstruction, shows the two subunits with unprecedented clarity. In the interior of the subunits, a complex distribution of higher mass density is recognized, which is attributed to ribosomal RNA. The masses corresponding to the 16S and 23S components are linked in the region of the platform of the small subunit. Thus the topography of the rRNA regions responsible for protein synthesis can be described.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
How cryo-EM is revolutionizing structural biology
Bai, X.-C., McMullan, G., & Scheres, S. H. W. (2015) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2014.10.005 · Cited by 936
Three-dimensional reconstruction of single particles embedded in ice
Penczek, P., Radermacher, M., & Frank, J. (1992) · Ultramicroscopy · doi:10.1016/0304-3991(92)90233-a · Cited by 458
Self-citationRibosome structures to near-atomic resolution from thirty thousand cryo-EM particles
Bai, X.-C., Fernandez, I. S., McMullan, G., & Scheres, S. H. (2013) · eLife · doi:10.7554/elife.00461 · Cited by 431
Penczek, P. A., Grassucci, R. A., & Frank, J. (1994) · Ultramicroscopy · doi:10.1016/0304-3991(94)90038-8 · Cited by 414
Self-citationThree-dimensional Reconstruction of theEscherichia coli30 S Ribosomal Subunit in Ice
Lata, K. R., Agrawal, R. K., Penczek, P., Grassucci, R., Zhu, J., & Frank, J. (1996) · Journal of Molecular Biology · doi:10.1006/jmbi.1996.0497 · Cited by 99
Self-citation
Metadata
- Authors
- Frank, J., Penczek, P., Grassucci, R., & Srivastava, S.
- Venue
- The Journal of cell biology
- Publisher
- Rockefeller University Press
- Published
- 1991-11-01
- Volume
- 115
- Issue
- 3
- Pages
- 597-605
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2140071307
- Cited by
- 171
- References
- 0
- FWCI
- 4.95
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Three-dimensional reconstruction of the 70S Escherichia coli ribosome in ice: the distribution of ribosomal RNA. https://app.cochat.ai/papers/10.1083/jcb.115.3.597
- The paper
- Frank, J., Penczek, P., Grassucci, R., & Srivastava, S. (1991). Three-dimensional reconstruction of the 70S Escherichia coli ribosome in ice: the distribution of ribosomal RNA. The Journal of cell biology. https://doi.org/10.1083/jcb.115.3.597
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
