The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
An analysis of vertebrate mRNA sequences: intimations of translational control.
Open accessAbstract
Five structural features in mRNAs have been found to contribute to the fidelity and efficiency of initiation by eukaryotic ribosomes. Scrutiny of vertebrate cDNA sequences in light of these criteria reveals a set of transcripts--encoding oncoproteins, growth factors, transcription factors, and other regulatory proteins--that seem designed to be translated poorly. Thus, throttling at the level of translation may be a critical component of gene regulation in vertebrates. An alternative interpretation is that some (perhaps many) cDNAs with encumbered 5' noncoding sequences represent mRNA precursors, which would imply extensive regulation at a posttranscriptional step that precedes translation.
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Cites
Kozak, M. (1986) · Cell · doi:10.1016/0092-8674(86)90762-2 · Cited by 4,741
Self-citationStructure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
Sun, X. J., Rothenberg, P., Kahn, C. R., Backer, J. M., Araki, E., Wilden, P. A., Cahill, D. A., Goldstein, B. J., & White, M. F. (1991) · Nature · doi:10.1038/352073a0 · Cited by 1,574
Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor
Takeshima, H., Nishimura, S., Matsumoto, T., Ishida, H., Kangawa, K., Minamino, N., Matsuo, H., Ueda, M., Hanaoka, M., Hirose, T., et al. (1989) · Nature · doi:10.1038/339439a0 · Cited by 1,146
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Structure and promoter activity of the gene for the erythroid transcription factor GATA-1.
Hannon, R., Evans, T., Felsenfeld, G., & Gould, H. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.8.3004 · Cited by 124
Cited by
The Glutamate Receptor Ion Channels
Dingledine, R., Borges, K., Bowie, D., & Traynelis, S. F. (1999) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01394-2 · Cited by 3,554
eIF4 Initiation Factors: Effectors of mRNA Recruitment to Ribosomes and Regulators of Translation
Gingras, A.-C., Raught, B., & Sonenberg, N. (1999) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.68.1.913 · Cited by 2,121
A protein related to extracellular matrix proteins deleted in the mouse mutant reeler
D'Arcangelo, G., G. Miao, G., Chen, S.-C., Scares, H. D., Morgan, J. I., & Curran, T. (1995) · Nature · doi:10.1038/374719a0 · Cited by 1,748
Regulation of translation initiation by FRAP/mTOR
Gingras, A.-C., Raught, B., & Sonenberg, N. (2001) · Genes & Development · doi:10.1101/gad.887201 · Cited by 1,545
Initiation of translation in prokaryotes and eukaryotes
Kozak, M. (1999) · Gene · doi:10.1016/s0378-1119(99)00210-3 · Cited by 1,364
Self-citation
Metadata
- Authors
- Kozak, M.
- Venue
- The Journal of cell biology
- Publisher
- Rockefeller University Press
- Published
- 1991-11-15
- Volume
- 115
- Issue
- 4
- Pages
- 887-903
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2049661143
- Cited by
- 1,635
- References
- 5
- FWCI
- 33.36
- Type
- journal article
- Language
- en
- Open access
- green
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