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CYTOPLASMIC COMPONENTS IN HEPATIC CELL LYSOSOMES
Open accessAbstract
De Duve and his colleagues, a few years ago, originated the concept of lysosomes based on the biochemical analysis of isolated cytoplasmic particles (1). He reported that a number of hydrolytic enzymes are concentrated in a fraction consisting of small subcellular units which sediments between the usual mitochondrial and microsomal fractions. Subsequent to this discovery, some of these properties have been demonstrated in hepatic pericanalicular dense bodies, and Essner and Novikoff (2), using the electron microscope, have shown that the enzyme product of acid phosphatase is found exclusively in these bodies. They have also found that a variety of pigment granules in human liver cells possess both
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Citations
Cited by
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Clarke, P. H. (1990) · Anatomy and Embryology · doi:10.1007/bf00174615 · Cited by 1,695
Autophagy in healthy aging and disease
Aman, Y., Schmauck-Medina, T., Hansen, M., Morimoto, R. I., Simon, A. K., Bjedov, I., Palikaras, K., Simonsen, A., Johansen, T., Tavernarakis, N., et al. (2021) · Nature Aging · doi:10.1038/s43587-021-00098-4 · Cited by 1,313
Proteolysis: from the lysosome to ubiquitin and the proteasome
Ciechanover, A. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1552 · Cited by 1,133
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Metadata
- Authors
- Ashford, T. P., & Porter, K. R.
- Venue
- The Journal of Cell Biology
- Publisher
- Rockefeller University Press
- Published
- 1962-01-01
- Volume
- 12
- Issue
- 1
- Pages
- 198-202
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2129687643
- Cited by
- 848
- References
- 0
- FWCI
- 33.87
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: CYTOPLASMIC COMPONENTS IN HEPATIC CELL LYSOSOMES. https://app.cochat.ai/papers/10.1083/jcb.12.1.198
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- Ashford, T. P., & Porter, K. R. (1962). CYTOPLASMIC COMPONENTS IN HEPATIC CELL LYSOSOMES. The Journal of Cell Biology. https://doi.org/10.1083/jcb.12.1.198
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
