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Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction.
Open accessAbstract
Epithelia and mesenchyme interact during various physiologic and pathologic processes. Scatter factor is a mesenchyme-derived cytokine that stimulates motility, proliferation, and morphogenesis of epithelia. Recent studies suggest that scatter factor and its receptor (c-met) mediate mesenchyme/epithelia signalling and even interconversion. In this mini-review, we will discuss how scatter factor and c-met may mediate interactions between mesenchyme and epithelia during embryogenesis, organ repair, and neoplasia.
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Cited by
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Jacobs, B. L., & Fornal, C. A. (1991) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06675-x · Cited by 269
Li, G., Schaider, H., Satyamoorthy, K., Hanakawa, Y., Hashimoto, K., & Herlyn, M. (2001) · Oncogene · doi:10.1038/sj.onc.1205034 · Cited by 212
Wang, V. E., Blaser, B. W., Patel, R. K., Behbehani, G. K., Rao, A. A., Durbin-Johnson, B., Jiang, T., Logan, A. C., Settles, M., Mannis, G. N., et al. (2021) · Blood Cancer Discovery · doi:10.1158/2643-3230.bcd-21-0055 · Cited by 11
Metadata
- Authors
- Rosen, E. M., Nigam, S. K., & Goldberg, I. D.
- Venue
- The Journal of cell biology
- Publisher
- Rockefeller University Press
- Published
- 1994-12-15
- Volume
- 127
- Issue
- 6
- Pages
- 1783-1787
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2060655489
- Cited by
- 277
- References
- 0
- FWCI
- 18.57
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction. https://app.cochat.ai/papers/10.1083/jcb.127.6.1783
- The paper
- Rosen, E. M., Nigam, S. K., & Goldberg, I. D. (1994). Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction. The Journal of cell biology. https://doi.org/10.1083/jcb.127.6.1783
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
