Kinesin Light Chains Are Essential for Axonal Transport in Drosophila
Gindhart, Joseph G., Desai, Chand J., Beushausen, Sven, Zinn, Kai, Goldstein, Lawrence S.B.·1998·The Journal of Cell Biology
Cited by (178)
Items 101–178 of 178
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- Rat kinesin light chain 3 associates with spermatid mitochondriaYing Zhang, Richard J. Oko, Frans A. van der Hoorn · 2004 · Developmental Biology
- The auto-inhibitory domain and ATP-independent microtubule-binding region of Kinesin heavy chain are major functional domains for transport in theDrosophilagermlineLucy S. Williams, Sujoy Ganguly, Philippe Loiseau, Bing Fu Ng, Isabel M. Palacios · 2013 · Development
- The Non-amyloidal Component Region of α-Synuclein Is Important for α-Synuclein Transport Within AxonsEric Nathaniel Anderson, Delnessaw Hirpa, Kan Hong Zheng, Rupkatha Banerjee, Shermali Gunawardena · 2020 · Frontiers in Cellular Neuroscience
- Association of Kinesin Light Chain with Outer Dense Fibers in a Microtubule-independent FashionBhupinder Bhullar, Ying Zhang, Albert Junco, Richard J. Oko, Frans A. van der Hoorn · 2003 · Journal of Biological Chemistry
- Hereditary spastic paraplegia with recessive trait caused by mutation in KLC4 geneFatih Bayraklı, Hatice Gamze Poyrazoğlu, Şirin Yüksel, Cengiz Yakıcıer, Bekir Ergüner, Mahmut Şamil Sağıroğlu, Betül Yücetürk, Buğra Özer, Selim Doganay, Bahattin Tanrıkulu et al. · 2015 · Journal of Human Genetics
- The Gene for the Intermediate Chain Subunit of Cytoplasmic Dynein Is Essential in DrosophilaKristin L.M. Boylan, Thomas S. Hays · 2002 · Genetics
- Disruption of Axonal Transport Perturbs Bone Morphogenetic Protein (BMP) - Signaling and Contributes to Synaptic Abnormalities in Two Neurodegenerative DiseasesMin‐Jung Kang, Timothy J. Hansen, Monique Mickiewicz, Tadeusz J. Kaczynski, Samantha Fye, Shermali Gunawardena · 2014 · PLoS ONE
- Drosophila Atlastin in motor neurons is required for locomotion and presynaptic functionCristian De Gregorio, Ricardo Delgado, Andrés Ibacache, Jimena A. Sierralta, Andrés Couve · 2017 · Journal of Cell Science
- KIF5C, a novel neuronal kinesin enriched in motor neuronsYoshimitsu Kanai · 2000 · Neuroscience Research
- Kinesin: the tail unfoldsRobert Anthony Cross, Jonathan M. Scholey · 1999 · Nature Cell Biology
- Kinesin-Ii, Coming and GoingDouglas G. Cole · 1999 · The Journal of Cell Biology
- Mechanisms controlling the trafficking, localization, and abundance of presynaptic Ca2+ channelsKaren L Cunningham, J. Troy Littleton · 2023 · Frontiers in Molecular Neuroscience
- Abl Tyrosine Kinase and Its Substrate Ena/VASP Have Functional Interactions with Kinesin-1MaryAnn Martin, Shawn M. Ahern-Djamali, F. Michael Hoffmann, William M. Saxton · 2005 · Molecular Biology of the Cell
- Clonal Tests of Conventional Kinesin Function during Cell Proliferation and DifferentiationRobert P. Brendza, Kathy B. Sheehan, F. Rudolf Turner, William M. Saxton · 2000 · Molecular Biology of the Cell
- A Functional Misexpression Screen Uncovers a Role for Enabled in Progressive NeurodegenerationCarolina Rezával, Jimena Berni, Ezequiel Axel Gorostiza, Santiago Werbajh, María Marta Fagilde, Maria P. Fernandez, Esteban J. Beckwith, Ezequiel J. Aranovich, Carmen Alejandra Sabio y García, M. Fernanda Ceriani · 2008 · PLoS ONE
- Activation by GDNF of a transcriptional program repressing neurite growth in dorsal root gangliaSten Linnarsson, Åsa Mikaels, Christel Baudet, Patrik Ernfors · 2001 · Proceedings of the National Academy of Sciences
- A stop or go switch: glycogen synthase kinase 3β phosphorylation of the kinesin 1 motor domain at Ser314 halts motility without detaching from microtubulesRupkatha Banerjee, Piyali Chakraborty, Michael C. Yu, Shermali Gunawardena · 2021 · Development
- Phosphoregulation of Kinesins Involved in Long-Range Intracellular TransportDiksha Kumari, Krishanu Ray · 2022 · Frontiers in Cell and Developmental Biology
- Molecular pathogenesis of peripheral neuropathies: insights from Drosophila modelsJulia Bussmann, Erik Storkebaum · 2017 · Current Opinion in Genetics & Development
- Vesicular Axonal Transport is Modified In Vivo by Tau Deletion or Overexpression in DrosophilaYasmina Talmat-Amar, Yoan Arribat, Marie‐Laure Parmentier · 2018 · International Journal of Molecular Sciences
- The Actin-Binding Protein Capulet Genetically Interacts with the Microtubule Motor Kinesin to Maintain Neuronal Dendrite HomeostasisPaul Mark B. Medina, Ryan J. Worthen, Lawrence J. Forsberg, Jay E. Brenman · 2008 · PLoS ONE
- Kinesins in the nervous systemMaryAnn Martin, Daryl D. Hurd, William M. Saxton · 1999 · Cellular and Molecular Life Sciences
- KLC4 shapes axon arbors during development and mediates adult behaviorElizabeth M. Haynes, Korri H Burnett, Jiaye He, Marcel W Jean-Pierre, Martin Jarzyna, Kevin W. Eliceiri, Jan Huisken, Mary C. Halloran · 2022 · eLife
- Unraveling the interplay of kinesin-1, tau, and microtubules in neurodegeneration associated with Alzheimer’s diseaseSiva Sundara Kumar Durairajan, Karthikeyan Selvarasu, Abhay Kumar Singh, Supriti Patnaik, Ashok Iyaswamy, Yogini Jaiswal, Leonard Lamont Williams, Jian‐Dong Huang · 2024 · Frontiers in Cellular Neuroscience
- The Overall Conformation of Conventional Kinesins Studied by Small Angle X-ray and Neutron ScatteringFrank Kozielski, Dmitri I. Svergun, Giuseppe Zaccaı̈, Richard H. Wade, Michel H. J. Koch · 2001 · Journal of Biological Chemistry
- Atlas stumbled: Kinesin light chain‐1 variant E triggers a vicious cycle of axonal transport disruption and amyloid‐β generation in Alzheimer's diseaseKathlyn J. Gan, Takashi Morihara, Michael A Silverman · 2014 · BioEssays
- The presenilin loop region is essential for glycogen synthase kinase 3 β (GSK3β) mediated functions on motor proteins during axonal transportRupkatha Banerjee, Zoe Rudloff, Crystal Naylor, Michael C. Yu, Shermali Gunawardena · 2018 · Human Molecular Genetics
- A Genetic Screen Based onin VivoRNA Imaging Reveals Centrosome-Independent Mechanisms for LocalizinggurkenTranscripts inDrosophilaRippei Hayashi, S. Mark Wainwright, Sophie J. Liddell, Sheena M. Pinchin, Stuart D. Horswell, David Ish‐Horowicz · 2014 · G3 Genes Genomes Genetics
- Axonal transport and neurodegenerative disease: vesicle-motor complex formation and their regulationShermali Gunawardena, Eric Nathaniel Anderson, Joseph White · 2014 · Degenerative Neurological and Neuromuscular Disease
- Kinesin-1 autoinhibition facilitates the initiation of dynein cargo transportRongde Qiu, Jun Zhang, Xin Xiang · 2022 · The Journal of Cell Biology
- The Neural Receptor Protein Tyrosine Phosphatase DPTP69D Is Required During Periods of Axon Outgrowth in DrosophilaChand J. Desai, Joy Purdy · 2003 · Genetics
- Synaptic dysfunction in disease and following injury in the developing and adult nervous system: Caveats in the choice of therapeutic intervention☆T GOULD, Ronald W. Oppenheim · 2007 · Neuroscience & Biobehavioral Reviews
- A Unique Role for Endothelial Cell Kinesin Light Chain 1, Variant 1 in Leukocyte Transendothelial MigrationBita F. Cyrus, William A. Müller · 2016 · American Journal Of Pathology
- Kinesin Light Chain 1 Suppression Impairs Human Embryonic Stem Cell Neural Differentiation and Amyloid Precursor Protein MetabolismRhiannon L. Killian, Jessica D. Flippin, Cheryl M. Herrera, Angels Almenar‐Queralt, Lawrence S.B. Goldstein · 2012 · PLoS ONE
- Role of Kinesin Heavy Chain in Crumbs Localization along the Rhabdomere Elongation in Drosophila PhotoreceptorGarrett P. League, Sang‐Chul Nam · 2011 · PLoS ONE
- Dynein catch bond as a mediator of codependent bidirectional cellular transportPalka Puri, Nisha Gupta, Sameep Chandel, Supriyo Naskar, Anil Nair, Abhishek Chaudhuri, Mithun K. Mitra, Sudipto Muhuri · 2019 · Physical Review Research
- Single Molecular Observation of Self-Regulated Kinesin MotilityTomonobu M. Watanabe, Toshio Yanagida, Atsuko Hikikoshi Iwane · 2010 · Biochemistry
- Kinesin DeliversPeter J. Hollenbeck · 2001 · The Journal of Cell Biology
- The Drosophila kinesin‐I associated protein YETI binds both kinesin subunitsTiffany Wisniewski, C.L. Tanzi, Joseph G. Gindhart · 2003 · Biology of the Cell
- Tau Protein: Function and PathologyHanna Rosenmann, David L Blum, Rakez Kayed, Lars Matthias Ittner · 2012 · International Journal of Alzheimer s Disease
- Drosophila Primary Neuronal Cultures as a Useful Cellular Model to Study and Image Axonal TransportAndré Voelzmann, Natalia Sánchez‐Soriano · 2022 · Methods in molecular biology
- PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transportParaskevi Tziortzouda, Jolien Steyaert, Wendy Scheveneels, Adrià Sicart, Katarina Stoklund Dittlau, Adriana Margarida Barbosa Correia, Thibaut Burg, Arun Pal, Andreas Hermann, Philip Van Damme et al. · 2024 · Acta Neuropathologica
- Techniques to Dissect Cellular and Subcellular Function in the Drosophila Nervous SystemHeinrich J. G. Matthies, Kendal S. Broadie · 2003 · Methods in cell biology
- Dynamic microtubule organization and mitochondrial transport are regulated by distinct Kinesin-1 pathwaysAnna Melkov, Yasmin Simchoni, Yehonatan Alcalay, Uri Abdu · 2015 · Biology Open
- Application of simple photobleaching microscopy techniques for the determination of the balance between anterograde and retrograde axonal transportAsparouh I. Iliev, Fred Silvester Wouters · 2006 · Journal of Neuroscience Methods
- Spatial and Temporal Characteristics of Normal and Perturbed Vesicle TransportGary J. Iacobucci, Noura Abdel Rahman, Aida Andrades Valtueña, Tapan K. Nayak, Shermali Gunawardena · 2014 · PLoS ONE
- Methods to identify and analyze gene products involved in neuronal intracellular transport using DrosophilaAmanda L. Neisch, Adam W. Avery, James B. Machamer, Min-gang Li, Thomas S. Hays · 2015 · Methods in cell biology
- Cytoplasmic Dynein Function Defined by Subunit CompositionK. Kevin Pfister, Kevin W.‐H. Lo · 2011 · Elsevier eBooks
- Characterization of kinesin-like proteins in silkworm posterior silkgland cellsQiao Wang, Junlin Teng, Birong Shen, Wei Zhang, Yige Guo, Xiaolei Su, Chuan‐Xi Zhang, Albert Cheung‐Hoi Yu, Jianguo Chen · 2010 · Cell Research
- Kinesin-1 promotes centrosome clustering and nuclear migration in the Drosophila oocyteMaëlys Loh, Fred Bernard, Antoine Guichet · 2023 · Development
- Purification of Kinesin from the BrainSergei A. Kuznetsov, Vladimir I. Gelfand · 2001 · Humana Press eBooks
- Loss and gain of motor protein function cause microtubule bundle damage in Drosophila axonsYu-Ting Liew, Milli Owens, David M.D. Bailey, William Cairns, Maureece Day, Ella Jones, Sophie McCann, Lydia Lorenzo-Cisneros, Thomas Murphy, Jill Parkin et al. · 2026 · Current Biology
- Different Mechanisms Link Gain and Loss of Kinesin Functions to Axonal DegenerationYu-Ting Liew, David M. Bailey, William Cairns, Maureece Day, Federico Dajas‐Bailador, Ella Jones, Sophie McCann, Matthias Landgraf, Lydia Lorenzo-Cisneros, Thomas Murphy et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- New cell biological explanations for kinesin-linked axon degenerationYu-Ting Liew, André Voelzmann, Liliana M. Pinho-Correia, Thomas Murphy, Haydn Tortoishell, Jill Parkin, David M. Bailey, Matthias Landgraf, Andreas Prokop · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Causal relationship between tinnitus and 8 psychiatric phenotypes: a Mendelian randomization studyTao Guo, Hui Xie · 2025 · European Archives of Psychiatry and Clinical Neuroscience
- Consequences of the Novel ALS-Associated KIF5A Variant c.2993-6C > A for Exon 27 Splicing and Axonal Transport of SFPQZiqi Yu, Jay P. Ross, Daniel L. Rochefort, Boting Li, Kate Bornais, Marvin Chum, Sali M.K. Farhan, Patrick A. Dion, Guy Armand Rouleau · 2026 · Neurology Genetics
- Trio analysis in dystonia identifies de novo KLC1 variants in a kinesinopathy with distinct motor and neurodevelopmental featuresElisa Peirano, Laura O’Regan, Philip Harrer, Ivana Dzinovic, Magda S. Chegkazi, Petra Havránková, Theresa Brunet, Rossella Capolino, Claudia Cesario, Stefania Ferro et al. · 2026 · EBioMedicine
- Identification of Kinesin-Associated ProteinsLisa C. Lindesmith, Janardan Kumar, Michael P. Sheetz · 2001 · Humana Press eBooks
- Drosophila cytoplasmic dyneinAmanda L. Neisch, Adam W. Avery, Min-gang Li, Thomas S. Hays · 2017 · Elsevier eBooks
- Structural Studies on Kinesin-1 Motor Domain and Light Chain from Rattus norvegicus and Neurospora crassaSpyridon Mylonas · 2005
- Boxing: The Preparticipation EvaluationFrancis O'Connor, James B. Tucker · 1991 · Military Medicine
- Clustering of the Endoplasmic Reticulum in Aluminum Induced ApoptosisAdam Nathan Hertlein · 2003 · Scholars Crossing (Liberty University)
- Crosslinking studies on the conventional kinesin of Neurospora crassaKatrin Hahlen · 2004 · Elektronische Hochschulschriften der LMU München (Ludwig-Maximilians-Universität München)
- Störungen des axonalen Transports bei der hereditären spastischen Spinalparalyse im Drosophila -ModellÄrztlicher Direktor, Thomas Gasser · 2011
- The β Subunit of Heterotrimeric G Protein Interacts Directly with Kinesin Heavy Chains, Kinesin-IDae‐Hyun Seog · 2010 · Journal of Life Science
- Restraint of the Wallenda/DLK MAP Kinase cascade by the Kinesin-3 motor regulates the assembly of synapsesJiaxing Li · 2017 · Deep Blue (University of Michigan)
- Desvendando as bases moleculares da síndrome SPOAN: deleção em homozigose em região regulatória leva à superexpressão do gene KLC2Uirá Souto Melo · 2017
- Computational methods for analyzing ngs data to discover clinically relevant mutationsBekir Ergüner · 2017 · Sabanci University
- Dynein catch bond as a mediator of codependent bidirectional cellular transportPalka Puri, Nisha Gupta, Sameep Chandel, Supriyo Naskar, Anil Nair, Abhishek Chaudhuri, Mithun Kumar Mitra, Sudipto Muhuri · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Cytoplasmic dynein function defined by subunit compositionK. Kevin Pfister · 2017 · Elsevier eBooks
- Motor protein disruption critically alters organelle trafficking, NMJ formation, and excitation contraction couplingHimanshu Bansal, Tadros A. Hana, Andrew H. Michael, Sevinch U. Kamaridinova, J. Bransford, Kiel G. Ormerod · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Endoplasmic reticulum stress-related genes contribute to lung cancer risk: a multiomics data integration studyZhaoxun Li, Suqin Wang, Zhen Yang, Fujun Yang, Jiayan Tan, Yaqin Wei, Esteban Cesar Gabazza, Mariacarmela Santarpía, Yimu Wu, Gening Jiang et al. · 2025 · Translational Lung Cancer Research
- Microtubule curling as an efficient readout to uncover fundamental concepts of axonal cell biology and neurodegenerationAndré Voelzmann, Milli Owens, Robin Beaven, William Cairns, Abigail Elliot, Sheng-Hui Feng, Judith B. Fülle, Catarina Gonçalves‐Pimentel, Ines Hahn, Ella Jones et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Genetic evidence for a functional association between Parkinson’s disease proteins leucine-rich repeat kinase 2 and α-synuclein during axonal transportPiyali Chakraborty, Pratima Bajgain, Jing Huang, Rakibul Islam, Rupkatha Banerjee, Shermali Gunawardena · 2026 · Frontiers in Molecular Neuroscience
- Étude de la toxicité neuronale induite par la protéine Tau dans la maladie d’Alzheimer, sur un modèle Invertébré : Drosophila melanogasterYasmina Talmat-Amar · 2012