Distinct Protein Sorting and Localization to Premelanosomes, Melanosomes, and Lysosomes in Pigmented Melanocytic Cells✪

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1. Mitochondrial NCKX5 regulates melanosomal biogenesis and pigment production
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2. Rab9A is required for delivery of cargo from recycling endosomes to melanosomes
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3. MHC Class II Presentation of gp100 Epitopes in Melanoma Cells Requires the Function of Conventional Endosomes and Is Influenced by Melanosomes
   Valentina Robila, Marina Ostankovitch, Michelle L. Altrich-VanLith, Alexander C. Theos, Sheila Drover, Michael S. Marks, Nicholas P. Restifo, Víctor H. Engelhard · 2008 · The Journal of Immunology
4. Heterologous expression of tyrosinase recapitulates the misprocessing and mistrafficking in oculocutaneous albinism type 2: Effects of altering intracellular pH and pink-eyed dilution gene expression
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5. An unconventional dileucine-based motif and a novel cytosolic motif are required for the lysosomal and melanosomal targeting of OA1
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6. Nuclear to non-nuclear Pmel17/gp100 expression (HMB45 staining) as a discriminator between benign and malignant melanocytic lesions
   Bonnie E. Gould Rothberg, Christopher B. Moeder, Harriet M. Kluger, Ruth Halaban, David E. Elder, Gëorge F. Murphy, Alexander J. Lazar, Victor Gerardo Prieto, Lynn McDivitt Duncan, David L. Rimm · 2008 · Modern Pathology
7. Micro RNAs upregulated in Vitiligo skin play an important role in its aetiopathogenesis by altering TRP1 expression and keratinocyte-melanocytes cross-talk
   Utpreksha Vaish, Avinash A. Kumar, Swati Varshney, Shreya Ghosh, Shantanu Sengupta, Chandni Sood, Hemanta Kumar Kar, Pankaj Sharma, Vivek T. Natarajan, Rajesh S. Gokhale et al. · 2019 · Scientific Reports
8. Multidrug Resistance Decreases with Mutations of Melanosomal Regulatory Genes
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9. Rab27b Association with Melanosomes: Dominant Negative Mutants Disrupt Melanosomal Movement
   Yanru Chen, Preminda Samaraweera, Tung‐Tien Sun, Gert Kreibich, Seth J. Orlow · 2002 · Journal of Investigative Dermatology
10. A BLOC‐1 mutation screen reveals a novel BLOC1S3 mutation in Hermansky–Pudlak Syndrome type 8
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11. Two SNPs in the SILV gene are associated with silver coat colour in ponies
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12. Analyzing Lysosome-Related Organelles by Electron Microscopy
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13. Why Study Functional Amyloids? Lessons from the Repeat Domain of Pmel17
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14. Faraway, so close! Functions of Endoplasmic reticulum–Endosome contacts
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15. Of Yeast, Mice, and Men
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16. How Rab proteins link motors to membranes
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17. Human Adipose Mesenchymal Cells Inhibit Melanocyte Differentiation and the Pigmentation of Human Skin via Increased Expression of TGF-β1
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18. Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH
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19. The secreted form of a melanocyte membrane‐bound glycoprotein (Pmel17/gp100) is released by ectodomain shedding
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20. Identification of Quinolines that Inhibit Melanogenesis by Altering Tyrosinase Family Trafficking
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21. A Novel Splice Variant of Pmel17 Expressed by Human Melanocytes and Melanoma Cells Lacking Some of the Internal Repeats
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22. Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle
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23. Uncoupling of ER/Mitochondrial Oxidative Stress in mTORC1 Hyperactivation-Associated Skin Hypopigmentation
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24. pH-Dependent fibril maturation of a Pmel17 repeat domain isoform revealed by tryptophan fluorescence
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25. PIKfyve complex regulates early melanosome homeostasis required for physiological amyloid formation
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26. The genetic basis and potential molecular mechanism of yellow-albino northern snakehead (Channa argus)
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27. Impaired Lysosomal Integral Membrane Protein 2-dependent Peroxiredoxin 6 Delivery to Lamellar Bodies Accounts for Altered Alveolar Phospholipid Content in Adaptor Protein-3-deficient pearl Mice
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28. Membrane trafficking in the retinal pigment epithelium at a glance
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29. Chapter 4 The Melanocortin‐1 Receptor Gene Polymorphism and Association with Human Skin Cancer
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30. Characterization of Melanosomes in Murine Hermansky–Pudlak Syndrome: Mechanisms of Hypopigmentation
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31. The Inhibition of Early N-Glycan Processing Targets TRP-2 to Degradation in B16 Melanoma Cells
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32. The integrated analysis of RNA-seq and microRNA-seq depicts miRNA-mRNA networks involved in Japanese flounder (Paralichthys olivaceus) albinism
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33. Rab4A organizes endosomal domains for sorting cargo to lysosome-related organelles
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34. Protein crowding mediates membrane remodeling in upstream ESCRT-induced formation of intraluminal vesicles
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35. Melanosomal Proteins – Role in Melanin Polymerization
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36. Using Sepia melanin as a PD model to describe the binding characteristics of neuromelanin – A critical review
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37. The ocular albinism type 1 (OA1) GPCR is ubiquitinated and its traffic requires endosomal sorting complex responsible for transport (ESCRT) function
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38. Vacuolar-type H+-ATPase with the a3 isoform is the proton pump on premature melanosomes
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39. ULK1 Regulates Melanin Levels in MNT-1 Cells Independently of mTORC1
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40. Identification of rab7 as a Melanosome-Associated Protein Involved in the Intracellular Transport of Tyrosinase-Related Protein 1
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41. Late Steps in Secretory Lysosome Exocytosis in Cytotoxic Lymphocytes
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42. The protease GtgE from Salmonella exclusively targets inactive Rab GTPases
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43. snow white, a Zebrafish Model of Hermansky-Pudlak Syndrome Type 5
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44. Glycolipid‐Dependent Sorting of Melanosomal from Lysosomal Membrane Proteins by Lumenal Determinants
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45. Extracellular vesicles released by keratinocytes regulate melanosome maturation, melanocyte dendricity, and pigment transfer
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46. C. elegans BLOC-1 Functions in Trafficking to Lysosome-Related Gut Granules
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47. The PKD domain distinguishes the trafficking and amyloidogenic properties of the pigment cell protein PMEL and its homologue GPNMB
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48. Heterogeneity of neural crest-derived melanocytes
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49. Endoplasmic Reticulum Export, Subcellular Distribution, and Fibril Formation by Pmel17 Require an Intact N-terminal Domain Junction
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50. Subcellular Localization of the Melanoma-associated Protein Melan-AMART-1 Influences the Processing of Its HLA-A2-restricted Epitope
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51. Surface Elastic Properties of Human Retinal Pigment Epithelium Melanosomes†
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52. Expression of OA1 limits the fusion of a subset of MVBs with lysosomes; a mechanism likely involved in the initial biogenesis of melanosomes
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53. The role of autophagy in skin pigmentation
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56. Aggrescan4D: structure-informed analysis of pH-dependent protein aggregation
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57. Single‐nucleotide polymorphisms in pigment genes and nonmelanoma skin cancer predisposition: a systematic review
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58. A BLOC-1–AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers
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59. Hyperacidification of Trans‐Golgi Network and Endo/Lysosomes in Melanocytes by Glucosylceramide‐Dependent V‐ATPase Activity
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60. Biogenesis of Melanosomes
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61. Genotype at thePMEL17locus affects social and explorative behaviour in chickens
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62. Hyperosmotic Stress Reduces Melanin Production by Altering Melanosome Formation
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63. Multiple A2E treatments lead to melanization of rod outer segment-challenged ARPE-19 cells.
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64. Atypical protein kinase Czeta suppresses migration of mouse melanoma cells.
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65. The Melanosomal Protein PMEL17 as a Target for Antibody Drug Conjugate Therapy in Melanoma
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66. The TYRP1‐mediated protection of human tyrosinase activity does not involve stable interactions of tyrosinase domains
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67. Sorting Out Signals in Fly Endosomes
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68. A Comprehensive Review of Mammalian Pigmentation: Paving the Way for Innovative Hair Colour-Changing Cosmetics
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69. Mitochondria–Melanocyte cellular interactions: An emerging mechanism of vitiligo pathogenesis
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70. CD4+ T-Cell Response to MitochondrialCytochrome bin Human Melanoma
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71. A polymethoxyflavone mixture extracted from orange peels, mainly containing nobiletin, 3,3’,4’,5,6,7,8-heptamethoxyflavone and tangeretin, suppresses melanogenesis through the acidification of cell organelles, including melanosomes
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72. Melanocytes in regenerative medicine applications and disease modeling
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73. Administration of a polyphenol-enriched feed to farmed sea bass (Dicentrarchus labrax L.): Kidney melanomacrophages response
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74. The Anti-Melanogenesis Effect of 3,4-Dihydroxybenzalacetone through Downregulation of Melanosome Maturation and Transportation in B16F10 and Human Epidermal Melanocytes
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75. The Many Faces of G Protein-Coupled Receptor 143, an Atypical Intracellular Receptor
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76. Rab7 Regulates Maturation of Melanosomal Matrix Protein gp100/Pmel17/Silv
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77. Plant Prevacuolar Compartments and Endocytosis
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78. Knockout of Hermansky-Pudlak Syndrome 4 (hps4) leads to silver-white tilapia lacking melanosomes
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79. Genetic architecture and evolution of color variation in American black bears
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80. The Pallidin (Pldn) Gene and the Role of SNARE Proteins in Melanosome Biogenesis
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81. The Melanosome: Dark Pigment Granule Shines Bright Light on Vesicle Biogenesis and More
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82. Accumulation of Tyrosinase in the Endolysosomal Compartment is Induced by U18666A
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83. Melasolv induces melanosome autophagy to inhibit pigmentation in B16F1 cells
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84. In vitro disease modeling of oculocutaneous albinism type 1 and 2 using human induced pluripotent stem cell-derived retinal pigment epithelium
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85. Melanocytes and keratinocytes morphological changes in vitiligo patients. A histological, immunohistochemical and ultrastructural analysis
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86. Myo sin VI Regulates Actin Dynamics and Melanosome Biogenesis
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87. Legal but lethal: functional protein aggregation at the verge of toxicity
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88. The Kringle-like Domain Facilitates Post-endoplasmic Reticulum Changes to Premelanosome Protein (PMEL) Oligomerization and Disulfide Bond Configuration and Promotes Amyloid Formation
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89. Abnormal Translocation of Tyrosinase and Tyrosinase-Related Protein 1 in Cutaneous Melanocytes of Hermansky–Pudlak Syndrome and in Melanoma Cells Transfected with Anti-Sense HPS1 cDNA
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90. Hermansky–Pudlak syndrome type 1 in patients of Indian descent
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91. Ubiquitin System-Dependent Regulation of Growth Hormone Receptor Signal Transduction
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92. La biogenèse des mélanosomes
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93. Multiple-labelling immunoEM using different sizes of colloidal gold: alternative approaches to test for differential distribution and colocalization in subcellular structures
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94. Reversing the Amyloid Trend: Mechanism of Fibril Assembly and Dissolution of the Repeat Domain from a Human Functional Amyloid
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96. Tyrosinase-related protein-2 and -1 are trafficked on distinct routes in B16 melanoma cells
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97. Alternative mechanisms of Notch activation by partitioning into distinct endosomal domains
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98. Genotype on the Pigmentation Regulating PMEL17 Gene Affects Behavior in Chickens Raised Without Physical Contact with Conspecifics
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99. Interaction between G Protein-Coupled Receptor 143 and Tyrosinase: Implications for Understanding Ocular Albinism Type 1
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100. Evidence that the small GTPase Rab8 is involved in melanosome traffic and dendrite extension in B16 melanoma cells
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