Distinct Protein Sorting and Localization to Premelanosomes, Melanosomes, and Lysosomes in Pigmented Melanocytic Cells✪

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Items 301–400 of 452

1. A β-solenoid model of the Pmel17 repeat domain: insights to the formation of functional amyloid fibrils
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2. ABCB6 Resides in Melanosomes and Regulates Early Steps of Melanogenesis Required for PMEL Amyloid Matrix Formation
   Ptissam Bergam, Johannes M. Reisecker, Zsófia Rakvács, Nóra Kucsma, Graça Raposo, Gergely Szakács, Guillaume van Niel · 2018 · Journal of Molecular Biology
3. Type II phosphatidylinositol 4-kinases function sequentially in cargo delivery from early endosomes to melanosomes
   Yueyao Zhu, Shuixing Li, Alexa Jaume, Riddhi Atul Jani, Cédric Delevoye, Graça Raposo, Michael S. Marks · 2022 · The Journal of Cell Biology
4. Study of Exosomes Shed New Light on Physiology of Amyloidogenesis
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5. Proteolysis of Rab32 by Salmonella GtgE induces an inactive GTPase conformation
   Sergey Savitskiy, Rudolf Wachtel, Danial Pourjafar‐Dehkordi, Hyun-Seo Kang, Vanessa Trauschke, Don C. Lamb, Michael Sattler, Martin Zacharias, Aymelt Itzen · 2020 · iScience
6. Differences in the melanosome distribution within the epidermal melanin units and its association with the impairing background of leukoderma in vitiligo and halo nevi: a retrospective study
   Xixi Xiong, Gaozhong Ding, Wen-E Zhao, Xue Li, Yu-Ting Ling, Li Sun, Qing-Li Gong, Yan Lu · 2017 · Archives of Dermatological Research
7. The refractive state of the eye in Icelandic horses with the Silver mutation
   Maria Rosengren, Kim Fegraeus, Gabriella Lindgren, Björn Ekesten · 2017 · BMC Veterinary Research
8. Enzymology of Melanin Formation
   Francisco Solano, José Carlos García-Borrón · 2006
9. Lipid transfer and metabolism across the endolysosomal–mitochondrial boundary
   Tiziana Daniele, Maria Vittoria Schiaffino · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
10. Modulating functional amyloid formation via alternative splicing of the premelanosomal protein PMEL17
    Dexter N. Dean, Jennifer C. Lee · 2020 · Journal of Biological Chemistry
11. The Menace of Melanoma: A Photodynamic Approach to Adjunctive Cancer Therapy
    Lester M. Davids, B. Kleem · 2013 · InTech eBooks
12. In Vitro Interaction of Melanoma-Derived Extracellular Vesicles with Collagen
    Roberta Palmulli, Enzo Bresteau, Graça Raposo, Guillaume Montagnac, Guillaume van Niel · 2023 · International Journal of Molecular Sciences
13. Use of comparative transcriptome analysis to identify candidate genes related to albinism in channel catfish (Ictalurus punctatus)
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14. Melanin reduction by peroxidase activity in lysosome-related organelle extracts from hen egg whites, HeLa cells, and Saccharomyces cerevisiae
    Jihee Yoon, Yang‐Hoon Kim, Ji‐Young Ahn, Hyun‐Cheol Lee, Suk‐Jung Oh, Bong‐Woo Chung, Jiho Min · 2015 · Molecular & Cellular Toxicology
15. Identification of an amyloid fibril forming segment of human Pmel17 repeat domain ( RPT domain)
    Nikolaos N. Louros, Vassiliki A. Iconomidou · 2015 · Biopolymers
16. Rab7 is a critical mediator in vesicular transport of tyrosinase‐related protein 1 in melanocytes
    Tokimasa Hida, Hitoshi Sohma, Yasuo Kokai, Akinori Kawakami, Kuninori Hirosaki, Masae Okura, Noriko Tosa, Toshiharu Yamashita, Kowichi Jimbow · 2010 · The Journal of Dermatology
17. The Role of DCT in HPV16 Infection of HaCaTs
    Pınar Aksoy, Patricio I Meneses · 2017 · PLoS ONE
18. AP-1/KIF13A Blocking Peptides Impair Melanosome Maturation and Melanin Synthesis
    Cécile Campagne, Léa Ripoll, Floriane Gilles-Marsens, Graça Raposo, Cédric Delevoye · 2018 · International Journal of Molecular Sciences
19. Melanosomes and MHC class II antigen-processing compartments
    Michael S. Marks, Alexander C. Theos, Graça Raposo · 2003 · Immunologic Research
20. Melanosome Processing in Keratinocytes
    Hugh Randolph Byers · 2006
21. Lysosomal Function and Intracellular Position Determine the Malignant Phenotype in Malignant Melanoma
    Ida Eriksson, Linda K. Vainikka, Petra Wäster, Karin M. Öllinger · 2023 · Journal of Investigative Dermatology
22. Direct observation of the effects of chemical fixation in MNT-1 cells: A SE-ADM and Raman study
    Rosangela Mastrangelo, Tomoko Okada, Taku Ogura, Toshihiko Ogura, Piero Baglioni · 2023 · Proceedings of the National Academy of Sciences
23. Comparative Transcriptome Analysis of Raccoon Dog Skin to Determine Melanin Content in Hair and Melanin Distribution in Skin
    Zhanyu Du, Kai Huang, Jiaping Zhao, Xingchao Song, Xiumei Xing, Qiong Wu, Linbo Zhang, Chao Xu · 2017 · Scientific Reports
24. Combined Action of Hyper-Harmonized Hydroxylated Fullerene Water Complex and Hyperpolarized Light Leads to Melanoma Cell Reprogramming In Vitro
    M. Markelic, Dijana Drača, Tamara Krajnović, Z. Jović, M. Vuksanović, D. Koruga, S. Mijatović, D. Maksimović-Ivanić · 2022 · Nanomaterials
25. Expression of Potential Targets for Cell-Based Therapies on Melanoma Cells
    Sophia Boyoung Strobel, Devayani Machiraju, Ingrid Hülsmeyer, Jürgen Christian Becker, Annette Paschen, Dirk Jäger, Winfried S. Wels, Michael Philipp Bachmann, Jessica C. Hassel · 2021 · Life
26. TheDominant whitemutation in thePMEL17gene does not cause visual impairment in chickens
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27. The Role of Phosphoinositide 3-Kinase in the Sorting and Transport of Newly Synthesized Tyrosinase-Related Protein-1 (TRP-1)
    Hua Chen, Thomas G. Salopek, Kowichi Jimbow · 2001 · Journal of Investigative Dermatology Symposium Proceedings
28. Arf6 Regulation of Gyrating‐Clathrin
    Yi Luo, Yi Zhan, James H. Keen · 2012 · Traffic
29. Silencing of PMEL attenuates melanization via activating lysosomes and degradation of tyrosinase by lysosomes
    Lijun Sun, Lei Hu, Ping Zhang, Huijin Li, Jingying Sun, Haifang Wang, Xin Xie, Jun X. Hu · 2018 · Biochemical and Biophysical Research Communications
30. Establishment and characterization of a primary and a metastatic melanoma cell line from Grey horses
    Monika Heidemarie Seltenhammer, Elisabeth Sundström, Claudia Meißlitzer-Ruppitsch, Petra Cejka, Jędrzej Kosiuk, Josef Neumüller, Marlene Almeder, Otto Majdic, Peter Steinberger, Udo M Losert et al. · 2013 · In Vitro Cellular & Developmental Biology - Animal
31. The Regulation of Melanin Formation
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32. Pmel17: controversial indeed but critical to melanocyte function
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33. Comparative transcriptome profiles of Lindian chicken eyelids identify melanin genes controlling eyelid pigmentation
    Hui Shu Yuan, X. Zhang, Q. Zhang, Y. Wang, S. Wang, Yueqi Li, Yu Zhang, J. Jing, J. Qiu, Z. Wang et al. · 2018 · British Poultry Science
34. Mahogunin Ring Finger 1 regulates pigmentation by controlling the pH of melanosomes in melanocytes and melanoma cells
    Julia Sirés-Campos, Ana Lambertos, Cédric Delevoye, Graça Raposo, Dorothy C. Bennett, Elena V. Sviderskaya, Celia Jiménez‐Cervantes, Concepción Olivares, José Carlos García-Borrón · 2021 · Cellular and Molecular Life Sciences
35. Attenuation Effect of Radiofrequency Irradiation on UV-B-Induced Skin Pigmentation by Decreasing Melanin Synthesis and through Upregulation of Heat Shock Protein 70
    Hyoung Moon Kim, Seyeon Oh, Chang Hu Choi, Jin Young Yang, Sung Geun Kim, Donghwan Kang, Kuk Hui Son, Kyunghee Byun · 2021 · Molecules
36. Reduced glutathione disrupts the intracellular trafficking of tyrosinase and tyrosinase-related protein-1 but not dopachrome tautomerase and Pmel17 to melanosomes, which results in the attenuation of melanization
    Hiroaki Nakajima, Takeshi Nagata, Shihiro Koga, Genji Imokawa · 2013 · Archives of Dermatological Research
37. Functional role of UNC13D in immune diseases and its therapeutic applications
    Van-Thanh Duong, Dongjun Lee, Yun Hak Kim, Sae‐Ock Oh · 2024 · Frontiers in Immunology
38. Cellular Lysosomes’ Activity for Melanin Reduction on Artificial Skin Tissue
    Dong Jun Park, Gyeongchan Jeon, Seung Hyuck Bang, Sang Yong Kim, Ji‐Hyang Wee, Yang‐Hoon Kim, Jiho Min · 2020 · Molecular Biotechnology
39. A Surgical Kit for Stem Cell-Derived Retinal Pigment Epithelium Transplants: Collection, Transportation, and Subretinal Delivery
    Kang V. Li, Miguel Flores‐Bellver, Silvia Aparicio‐Domingo, Carson C. Petrash, Hannah Cobb, Conan Y. Chen, M. Valeria Canto-Soler, Marc T. Mathias · 2022 · Frontiers in Cell and Developmental Biology
40. TRPA1 promotes UVB‐induced skin pigmentation by regulating melanosome luminal pH
    Wei Wu, Yupeng Wang, Ying Liu, Handan Guo, Zhou Li, Wei Zou, Jing Liu, Zhiqi Song · 2022 · Experimental Dermatology
41. FIG4, Charcot‐Marie‐Tooth disease, and hypopigmentation: a role for phosphoinositides in melanosome biogenesis?
    Michael S. Marks · 2007 · Pigment Cell & Melanoma Research
42. Expression of constructs of the neuronal isoform of myosin‐Va interferes with the distribution of melanosomes and other vesicles in melanoma cells
    João Carlos da Silva Bizário, Alexandra A.C. Nascimento, Luciana Casaletti, Eliana Valéria Patussi, Maria Fernanda Chociay, Roy Edward Larson, Enilza Maria Espreáfico · 2002 · Cell Motility and the Cytoskeleton
43. Endocytic prolactin routes to the secretory pathway in lactating mammary epithelial cells
    Touria Seddiki, Serge Delpal, Alain Aubourg, Georges Durand, Michèle Ollivier‐Bousquet · 2002 · Biology of the Cell
44. Urinary Exosomes for Protein Biomarker Research
    Delfin Albert Amal Raj, Immacolata Fiume, Giovambattista Capasso, Gabriella Pòcsfalvi · 2012 · InTech eBooks
45. Synthesis and role of melanin for toleratingin vitrorumen digestion inDuddingtonia flagrans, a nematode-trapping fungus
    Deivid França Freitas, Olney Vieira‐da‐Motta, L.D.S. Mathias, R. Franco, Raphael dos Santos Gomes, Ricardo Augusto Mendonça Vieira, Letícia Oliveira da Rocha, Fábio Lopes Olivares, Clóvis de Paula Santos · 2019 · Mycology&#58 An International Journal on Fungal Biology
46. Pyridinyl imidazole compounds interfere with melanosomes sorting through the inhibition of Cyclin G-associated Kinase, a regulator of cathepsins maturation
    Barbara Bellei, Angela Pitisci, Emilia Migliano, Giorgia Cardinali, Mauro Picardo · 2014 · Cellular Signalling
47. Degradation of Tyrosinase by Melanosomal pH Change and a New Mechanism of Whitening with Propylparaben
    Haifeng Zeng, 茜 原島, Koichi Kato, Lihao Gu, Yosuke Motomura, Ryoichi Otsuka, Kazuhisa Maeda · 2017 · Cosmetics
48. A role for Dynlt3 in melanosome movement, distribution, acidity and transfer
    Zackie Aktary, Alejandro Conde‐Perez, Florian Rambow, Mathilde Di Marco, François Amblard, Ilse Hurbain, Graça Raposo, Cédric Delevoye, Sylvie Coscoy, Lionel Larue · 2021 · Communications Biology
49. Identification of critical amino acid residues in the regulatory N-terminal domain of PMEL
    Susan M. Mitchell, Morven M. Graham, Xinran Liu, Ralf M. Leonhardt · 2021 · Scientific Reports
50. Biogenesis of Melanosomes
    Delevoye, Cédric, Giordano, Francesca, Marks, Michael S., Raposo, Graça · 2011 · Melanins and Melanosomes
51. Genetics of Skin, Hair, and Eye Color in Human Pigmentation Disorders
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52. Bleaching and Oxidation of Human Hair
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53. Rapid Isolation of Rare Isotype-Switched Hybridoma Variants: Application to the Generation of IgG2a and IgG2b MAb to CD63, a Late Endosome and Exosome Marker
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54. Dense and Acidic Organelle-Targeted Visualization in Living Cells: Application of Viscosity-Responsive Fluorescence Utilizing Restricted Access to Minimum Energy Conical Intersection
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55. Cryo-EM of wild-type and mutant PMEL amyloid cores reveals structural mechanism of pigment dispersion syndrome
    Haruaki Yanagisawa, Harumi Arai, Tony Wang, Hideyuki Miyazawa, Masahide Kikkawa, Toshiyuki Oda · 2025 · Nature Communications
56. Reprogramming of endolysosomes for melanogenesis in BLOC-1-deficient melanocytes
    Philip S. Goff, Shyamal Patel, Dawn C. Harper, Tom D. Carter, Michael S. Marks, Elena V. Sviderskaya · 2025 · Current Biology
57. Effects of domestication related genes on behaviour, physiology and gene expression in chickens
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58. A Novel Method for Visualizing Melanosome and Melanin Distribution in Human Skin Tissues
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59. Lethal (2) giant discs (Lgd)/CC2D1 is required for the full activity of the ESCRT machinery
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60. Purification and characterization of an amyloidogenic repeat domain from the functional amyloid Pmel17
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61. A mutation within the transmembrane domain of melanosomal protein Silver (Pmel17) changes lumenal fragment interactions
    Regina Kuliawat, Laura Santambrogio · 2009 · European Journal of Cell Biology
62. Different expression of lysosome-associated membrane protein-1 in human melanomas and benign melanocytic lesions
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63. The Surface Oxidation Potential of Melanosomes Measured by Free Electron Laser-Photoelectron Emission Microscopy
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64. Biogenesis of fibrils requires C‐mannosylation of PMEL
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65. PTPN23-dependent ESCRT machinery functions as a cell death checkpoint
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66. Antibody αPEP13h Reacts With Lymphangioleiomyomatosis Cells in Lung Nodules
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67. Pathological modelling of pigmentation disorders associated with Hutchinson-Gilford Progeria Syndrome (HGPS) revealed an impaired melanogenesis pathway in iPS-derived melanocytes
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68. The lysosomal chloride-proton exchanger CLC7 functions in melanosomes as a negative regulator of human pigmentation
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69. Amorphigenin from Amorpha fruticosa L. Root Extract Induces Autophagy-Mediated Melanosome Degradation in mTOR-Independent- and AMPK-Dependent Manner
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70. Intermittent inhibition of FYVE finger-containing phosphoinositide kinase induces melanosome degradation in B16F10 melanoma cells
    Kyoka Kawaguchi, Miyu Watanabe, Saho Furukawa, Kenichi Koga, Hiromitsu Kanamori, Mitsushi J. Ikemoto, Shigeo Takashima, Miwa Maeda, Kentaro Oh‐hashi, Yoko Hirata et al. · 2023 · Molecular Biology Reports
71. Phosphorylation of glucocorticoid receptor induced by 16‐kauren‐2‐beta‐18, 19‐triol decreases expression of Melanophilin through JNK signalling
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72. Single organelle measurements of melanosome pH using the novel ratiometric indicator RpHiMEL
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73. The role of SLC24A5 in skin color
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74. Ultrastructural observations of human epidermal melanocytes cultured on polyethylene terephthalate film
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75. Molecular Genetics of Hermansky–Pudlak Syndrome
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76. A genome-wide genetic screen uncovers novel determinants of human pigmentation
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77. Darkness descends with two Rabs
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78. Membrane-Associated Ubiquitin Ligase RING Finger Protein 152 Orchestrates Melanogenesis via Tyrosinase Ubiquitination
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79. Que “ trafiquent ” les mélanosomes ?
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80. Specialised features of melanosomes in health and disease in the retinal pigment epithelium
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81. Identification of a RAB32-LRMDA-Commander membrane trafficking complex reveals the molecular mechanism of human oculocutaneous albinism type 7
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82. Integrative Transcriptomic and Proteomic Profiling Identifies PMEL as a Critical Regulator of Melanogenesis in Rex Rabbits
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83. Insights into lysosome-related organelle biogenesis: melanosome as a model organelle
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84. Integrative transcriptomics and metabolomics analysis provide insight into the formation of skin pigmentation diversity in Chinese soft-shelled turtle (Pelodiscus sinensis)
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85. Keratin intermediate filaments mechanically position melanin pigments for genome photoprotection
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86. A New Anorectal Melanoma Cell Line Derived from a Primary Human Rectal Tumor
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87. Melanocyte Pygmentation – Friend or Foe on the Route to Melanoma
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88. Novel loss-of-function variant in DENND5A impedes melanosomal cargo transport and predisposes to familial cutaneous melanoma
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89. Lysosome‐Related Organelles: Modifications of the Lysosome Paradigm
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90. Dense and Acidic Organelle-Targeted Visualization in Living Cells using a Viscosity-Responsive Fluorescent Probe Independent of the Twisted Intramolecular Charge Transfer Process
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91. The clues offered by SNAREs on the vacuoles of plants and animals
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92. Functional and Morphological Plasticity of the Endolysosomal System: Pigment Organelles at the Crossroads of Physiology and Pathology
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93. Albinism: from genetics to cell biology and physiopathology
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94. In Situ Protein Expression Analysis of Melanocyte Differentiation Antigen TRP1 (Tyrosinase-Related Protein-1)
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95. MFF budding from mitochondria regulates melanosome size and maturation
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96. A Melanosome-associated Monoclonal Antibody J1 Recognizes Luminal Membrane of Prelysosomes Common to Biogenesis of Melanosomes and Lysosomes.
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97. THE TRAFFIC ROUTES OF TYROSINASES ON THEIR WAY TOWARDS MELANOSOMES
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98. Heuristic Modelling Applied to Epidermal Homeostasis
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99. Proteomic analysis of lysosomal proteins in melanocyte B16F10 exposed to melanin
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100. Pmela and Tyrp1b Contribute to Melanophore Variation in Mexican Cavefish
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