The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Cell motility through plasma membrane blebbing
Open accessAbstract
Plasma membrane blebs are dynamic cytoskeleton-regulated cell protrusions that have been implicated in apoptosis, cytokinesis, and cell movement. Influencing Rho–guanosine triphosphatase activities and subsequent actomyosin dynamics appears to constitute a core component for bleb formation. In this paper, we discuss recent evidence in support of a central role of nonapoptotic membrane blebbing for cell migration and cancer cell invasion as well as advances in our understanding of the underlying molecular mechanisms. Based on these studies, we propose that in a physiological context, bleb-associated cell motility reflects a cell's response to reduced substratum adhesion. The importance of blebbing as a functional protrusion is underscored by the existence of multiple molecular mechanisms that govern actin-mediated bleb retraction.
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Cites
Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing
Sebbagh, M., Renvoizé, C., Hamelin, J., Riché, N., Bertoglio, J., & Bréard, J. (2001) · Nature Cell Biology · doi:10.1038/35070019 · Cited by 915
Raucher, D., Stauffer, T., Chen, W., Shen, K., Guo, S., York, J. D., Sheetz, M. P., & Meyer, T. (2000) · Cell · doi:10.1016/s0092-8674(00)81560-3 · Cited by 675
PDK1 Regulates Cancer Cell Motility by Antagonising Inhibition of ROCK1 by RhoE
Pinner, S., & Sahai, E. (2008) · Nature Cell Biology · doi:10.1038/ncb1675 · Cited by 267
Cited by
Pyroptosis: Mechanisms and Diseases
Yu, P., Zhang, X., Liu, N., Tang, L., Peng, C., & Chen, X. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00507-5 · Cited by 2,353
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
Friedl, P., & Alexander, S. (2011) · Cell · doi:10.1016/j.cell.2011.11.016 · Cited by 1,940
In vitro cell migration and invasion assays
Kramer, N., Walzl, A., Unger, C., Rosner, M., Krupitza, G., Hengstschläger, M., & Dolznig, H. (2013) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2012.08.001 · Cited by 1,170
Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis
Nomura, D. K., Long, J. Z., Niessen, S., Hoover, H. S., Ng, S.-W., & Cravatt, B. F. (2010) · Cell · doi:10.1016/j.cell.2009.11.027 · Cited by 1,002
Actin cortex mechanics and cellular morphogenesis
Salbreux, G., Charras, G., & Paluch, E. (2012) · Trends in Cell Biology · doi:10.1016/j.tcb.2012.07.001 · Cited by 871
Metadata
- Authors
- Fackler, O. T., & Grosse, R.
- Venue
- The Journal of Cell Biology
- Publisher
- Rockefeller University Press
- Published
- 2008-06-09
- Volume
- 181
- Issue
- 6
- Pages
- 879-884
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2111711361
- Cited by
- 588
- References
- 3
- FWCI
- 16.16
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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