The position of lysosomes within the cell determines their luminal pH

Johnson, Danielle E., Ostrowski, Philip, Jaumouillé, Valentin, Grinstein, Sergio·2016·Journal of Cell Biology

Cited by (591)

Items 101–200 of 591

  1. Protecting cells by protecting their vulnerable lysosomes: Identification of a new mechanism for preserving lysosomal functional integrity upon oxidative stress
    Raquel Pascua‐Maestro, Sergio Diez‐Hermano, Concepción Lillo, María Dolores Ganfornina, Diego Sánchez · 2017 · PLoS Genetics
  2. Whole-Cell Scale Dynamic Organization of Lysosomes Revealed by Spatial Statistical Analysis
    Qinle Ba, Guruprasad Raghavan, Kirill I. Kiselyov, Ge Yang · 2018 · Cell Reports
  3. LRRC8 family proteins within lysosomes regulate cellular osmoregulation and enhance cell survival to multiple physiological stresses
    Ping Li, Meiqin Hu, Ce Wang, Xinghua Feng, Zhuangzhuang Zhao, Ying Yang, Nirakar Sahoo, Mingxue Gu, Yexin Yang, Shiyu Xiao et al. · 2020 · Proceedings of the National Academy of Sciences
  4. The Journey of the Synaptic Autophagosome: A Cell Biological Perspective
    Kargbo-Hill, Sarah E., Colón-Ramos, Daniel A. · 2020 · Neuron
  5. Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus
    Alexander Kühnl, Agnes Musiol, Nicole Heitzig, Danielle Johnson, Christina Ehrhardt, Thomas Grewal, Volker Gerke, Stephan Ludwig, Ursula Rescher · 2018 · mBio
  6. Autophagy in cancer cell remodeling and quality control
    Grace A. Hernandez, Rushika M. Perera · 2022 · Molecular Cell
  7. Disrupted degradative sorting of TLR7 is associated with human lupus
    Harshita Mishra, Claire Schlack-Leigers, Ee Lyn Lim, Oliver Thieck, Thomas Magg, Johannes Raedler, Christine Wolf, Christoph Klein, Helge Ewers, Min Ae Lee‐Kirsch et al. · 2024 · Science Immunology
  8. Tumor microenvironment-targeted poly-L-glutamic acid-based combination conjugate for enhanced triple negative breast cancer treatment
    Juan José Arroyo‐Crespo, Ana Armiñán, David Charbonnier, Leandro Balzano‐Nogueira, Francisco Huertas, Cristina Martí, Sonia Tarazona, Jerónimo Forteza, Ana Conesa, Maria Jesus Vicent · 2018 · Biomaterials
  9. RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin
    Tal Keren‐Kaplan, Amra Sarić, Saikat Ghosh, Chad D. Williamson, Rui Jia, Yan Li, Juan S. Bonifacino · 2022 · Nature Communications
  10. The unconventional secretion of IL-1β: Handling a dangerous weapon to optimize inflammatory responses
    Roberto Sitia, Anna Rubartelli · 2018 · Seminars in Cell and Developmental Biology
  11. The Arf-like GTPase Arl8b is essential for three-dimensional invasive growth of prostate cancer <i>in vitro</i> and xenograft formation and growth <i>in vivo</i>
    Dykes, Samantha S., Gray, Alana L., Coleman, David T., Saxena, Madhurima, Stephens, Charles A., Carroll, Jennifer L., Pruitt, Kevin, Cardelli, James A. · 2016 · Oncotarget
  12. The three-dimensional landscape of cortical chromatin accessibility in Alzheimer’s disease
    Bendl, Jaroslav, Hauberg, Mads E., Girdhar, Kiran, Im, Eunju, Vicari, James M., Rahman, Samir, Fernando, Michael B., Townsley, Kayla G., Dong, Pengfei, Misir, Ruth et al. · 2022 · Nature Neuroscience
  13. A cell-based assay for CD63-containing extracellular vesicles
    Anil G. Cashikar, Phyllis I. Hanson · 2019 · PLoS ONE
  14. Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication
    Aastha Sindhwani, Subhash B. Arya, Harmeet Kaur, Divya Jagga, Amit Tuli, Mahak Sharma · 2017 · PLoS Pathogens
  15. Rab and Arf proteins at the crossroad between membrane transport and cytoskeleton dynamics
    Ingrid Kjos, Katharina Vestre, Noemi Antonella Guadagno, Marita Borg Distefano, Cinzia Progida · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  16. Acidic nanoparticles protect against α‐synuclein‐induced neurodegeneration through the restoration of lysosomal function
    Marie-Laure Arotçarena, Federico Nicolás Soria, Anthony Cunha, Évelyne Doudnikoff, Geoffrey Prévot, Jonathan Daniel, Mireille H. Blanchard-Desce, Philippe Barthélémy, Erwan Bézard, Sylvie Crauste–Manciet et al. · 2022 · Aging Cell
  17. Carnosine regulation of intracellular pH homeostasis promotes lysosome-dependent tumor immunoevasion
    Ronghui Yan, Pinggen Zhang, Shengqi Shen, Yu Zeng, Ting Wang, Zhaolin Chen, Wenhao Ma, Junru Feng, Caixia Suo, Tong Zhang et al. · 2024 · Nature Immunology
  18. Myc‐nick promotes efferocytosis through M2 macrophage polarization during resolution of inflammation
    Xiancai Zhong, Hana Lee, Seung Hyeon Kim, Sin‐Aye Park, Won‐Ki Kim, Young‐Nam Cha, Young‐Joon Surh · 2018 · The FASEB Journal
  19. Modulation of RAB7A Protein Expression Determines Resistance to Cisplatin through Late Endocytic Pathway Impairment and Extracellular Vesicular Secretion
    Flora Guerra, Aurora Paiano, Danilo Migoni, Giulia Girolimetti, Anna Myriam Perrone, Pierandrea De Iaco, Francesco Paolo Fanizzi, Giuseppe Gasparre, Cecilia Bucci · 2019 · Cancers
  20. A role for Rab11 in the homeostasis of the endosome-lysosomal pathway
    Zulkefli, Khalisah L., Houghton, Fiona J., Gosavi, Prajakta, Gleeson, Paul A. · 2019 · Experimental Cell Research
  21. Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca 2+ efflux and disrupted by PSEN1 loss of function
    Pearl P.Y. Lie, Lang Yoo, Chris N. Goulbourne, Martin J. Berg, Philip H. Stavrides, Chunfeng Huo, Ju‐Hyun Lee, Ralph A. Nixon · 2022 · Science Advances
  22. Balancing lysosome abundance in health and disease
    Anders Peter Mutvei, Michal J. Nagiec, John Blenis · 2023 · Nature Cell Biology
  23. Mitochondrial translation deficiency impairs NAD+‐mediated lysosomal acidification
    Mikako Yagi, Takahiro Toshima, Rie Amamoto, Yura Do, Haruka Hirai, Daiki Setoyama, Dongchon Kang, Takeshi Uchiumi · 2021 · The EMBO Journal
  24. Annexins A1 and A2 are recruited to larger lysosomal injuries independently of ESCRTs to promote repair
    Willa Wen‐You Yim, Hayashi Yamamoto, Noboru Mizushima · 2022 · FEBS Letters
  25. Elevated Cholesterol in the Coxiella burnetii Intracellular Niche Is Bacteriolytic
    Minal Mulye, Dhritiman Samanta, Seth Winfree, Robert A. Heinzen, Stacey D. Gilk · 2017 · mBio
  26. Liver sinusoidal endothelial cells contribute to the uptake and degradation of entero bacterial viruses
    Cristina Ionica Øie, Deanna Lynn Wolfson, Yasunori Tanji, Gianina Dumitriu, Karen Kristine Sørensen, Peter McCourt, Balpreet Singh Ahluwalia, Bård H. Smedsrød · 2020 · Scientific Reports
  27. Cresyl violet: a superior fluorescent lysosomal marker
    Philip P. Ostrowski, Gregory D. Fairn, Sergio Grinstein, Danielle Johnson · 2016 · Traffic
  28. The Lysosomotropic Activity of Hydrophobic Weak Base Drugs is Mediated via Their Intercalation into the Lysosomal Membrane
    Michal Stark, Tomás F. D. Silva, Guy Levin, Miguel Machuqueiro, Yehuda G. Assaraf · 2020 · Cells
  29. A lysosomal chloride ion-selective fluorescent probe for biological applications
    Sang-Hyun Park, Ji Young Hyun, Injae Shin · 2018 · Chemical Science
  30. The Cell Biology of Tau Secretion
    Maria Merezhko, Riikka‐Liisa Uronen, Henri J. Huttunen · 2020 · Frontiers in Molecular Neuroscience
  31. Imaging the electrical activity of organelles in living cells
    Ella Matamala, Cristian Castillo, Juan Pablo Vivar, Patricio A. Rojas, Sebastian E. Brauchi · 2021 · Communications Biology
  32. The lysosomal storage disease continuum with ageing-related neurodegenerative disease
    Emyr Lloyd‐Evans, Luke J. Haslett · 2016 · Ageing Research Reviews
  33. Multi–Cell Line Analysis of Lysosomal Proteomes Reveals Unique Features and Novel Lysosomal Proteins
    2023
  34. Multi cell line analysis of lysosomal proteomes reveals unique features and novel lysosomal proteins
    Akter, Fatema, Ponnaiyan, Srigayatri, Kögler-Mohrbacher, Bianca, Bleibaum, Florian, Damme, Markus, Renard, Bernhard Y., Winter, Dominic · 2020
  35. Consecutive functions of small GTPases guide HOPS-mediated tethering of late endosomes and lysosomes
    Ariane Schleinitz, Lara-Alina Pöttgen, Tal Keren‐Kaplan, Jing Pu, Paul Säftig, Juan S. Bonifacino, Albert Haas, Andreas Jeschke · 2023 · Cell Reports
  36. Drosophila TMEM63 and mouse TMEM63A are lysosomal mechanosensory ion channels
    Kai Li, Yanmeng Guo, Yayu Wang, Ruijun Zhu, Wei Chen, Tong Cheng, Xiaofan Zhang, Yinjun Jia, Ting Liu, Wei Zhang et al. · 2024 · Nature Cell Biology
  37. Loss of Christianson Syndrome Na + /H + Exchanger 6 (NHE6) Causes Abnormal Endosome Maturation and Trafficking Underlying Lysosome Dysfunction in Neurons
    Matthew F. Pescosolido, Qing Ouyang, Judy Shih-Hwa Liu, Eric M. Morrow · 2021 · Journal of Neuroscience
  38. Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance
    Johannes Ridinger, Emily Koeneke, Fiona R. Kolbinger, Katharina F. Körholz, Siavosh Mahboobi, Lars Hellweg, Nikolas Gunkel, Aubry K. Miller, Heike Peterziel, Peter Schmezer et al. · 2018 · Scientific Reports
  39. Hemozoin produced by mammals confers heme tolerance
    Rini H Pek, Xiaojing Yuan, Nicole Rietzschel, Jianbing Zhang, Laurie K. Jackson, Eiji Nishibori, Ana Cristina Ribeiro, William R. Simmons, Jaya Jagadeesh, Hiroshi Sugimoto et al. · 2019 · eLife
  40. Fluorescent nano- and microparticles for sensing cellular microenvironment: past, present and future applications
    Giuliana Grasso, Francesco Colella, Stefania Forciniti, Valentina Onesto, Helena Iuele, Anna Chiara Siciliano, Federica Carnevali, Anil Chandra, Giuseppe Gigli, Loretta L. del Mercato · 2023 · Nanoscale Advances
  41. pH of endophagosomes controls association of their membranes with Vps34 and PtdIns(3)P levels
    Amriya Naufer, Victoria E. B. Hipolito, Suriakarthiga Ganesan, Akriti Prashar, Vanina Zaremberg, Roberto J. Botelho, Mauricio R. Terebiznik · 2017 · The Journal of Cell Biology
  42. Human protein paucimannosylation: cues from the eukaryotic kingdoms
    Harry C. Tjondro, Ian Loke, S. Chatterjee, M. Thaysen-Andersen · 2019 · Biological Reviews of The Cambridge Philosophical Society
  43. Spatial localization of cathepsins: Implications in immune activation and resolution during infections
    Elsa Anes, David Pires, Manoj Mandal, José Miguel Azevedo‐Pereira · 2022 · Frontiers in Immunology
  44. TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry
    Luigi Sbano, Massimo Bonora, Saverio Marchi, Federica Baldassari, Diego Luis Medina, Andrea Ballabio, Carlotta Giorgi, Paolo Pinton · 2017 · Scientific Reports
  45. Molecular Mechanisms of Lysosome and Nucleus Communication
    Qian Zhao, Shihong Max Gao, Meng Carla Wang · 2020 · Trends in Biochemical Sciences
  46. Janus sword actions of chloroquine and hydroxychloroquine against COVID-19
    Xuesong Chen, Jonathan D. Geiger · 2020 · Cellular Signalling
  47. The Lysosome and Intracellular Signalling.
    G. Hesketh, L. Wartosch, Luther J. Davis, Nicholas A. Bright, J. P. Luzio · 2018 · Progress in molecular and subcellular biology
  48. Coxiella burnetii Type 4B Secretion System-dependent manipulation of endolysosomal maturation is required for bacterial growth
    Dhritiman Samanta, Tatiana Mordente Clemente, Baleigh E. Schuler, Stacey D. Gilk · 2019 · PLoS Pathogens
  49. ARL8B mediates lipid droplet contact and delivery to lysosomes for lipid remobilization
    Dilip Menon, Apoorva Bhapkar, Bhoomika Manchandia, Gitanjali Charak, Surabhi Rathore, Rakesh Mohan Jha, Arpita Nahak, Moumita Mondal, Mohyeddine Omrane, Akash Kumar Bhaskar et al. · 2023 · Cell Reports
  50. Lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension
    Lloyd D. Harvey, Mona Alotaibi, Yi‐Yin Tai, Ying Tang, Hee‐Jung J. Kim, Neil J. Kelly, Wei Sun, Chen-­Shan Chen Woodcock, Sanya Arshad, Miranda K. Culley et al. · 2025 · Science
  51. Evolution, role in inflammation, and redox control of leaderless secretory proteins
    Roberto Sitia, Anna Rubartelli · 2020 · Journal of Biological Chemistry
  52. The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway
    Tom Cremer, Marlieke L.M. Jongsma, Fredrik Trulsson, Alfred C.O. Vertegaal, Jacques Neefjes, Ilana Berlin · 2021 · Cell Reports
  53. Rab11 is required for lysosome exocytosis through the interaction with Rab3a, Sec15 and GRAB
    Cristina Escrevente, Liliana Bento‐Lopes, Jose Silva Ramalho, Duarte C. Barral · 2021 · Journal of Cell Science
  54. DGAT1 activity synchronises with mitophagy to protect cells from metabolic rewiring by iron depletion
    Maeve Long, Álvaro Sánchez-Martínez, Marianna Longo, Fumi Suomi, Hans C. Stenlund, Annika I. Johansson, Homa Ehsan, Veijo T. Salo, Lambert Montava‐Garriga, Seyedehshima Naddafi et al. · 2022 · The EMBO Journal
  55. Intracellular Insulin and Impaired Autophagy in a Zebrafish model and a Cell Model of Type 2 diabetes
    Xianghui Meng, Bo Chen, Jingpu Zhang · 2017 · International Journal of Biological Sciences
  56. Lysosomal positioning diseases: beyond substrate storage
    Gianluca Scerra, Valeria De Pasquale, Melania Scarcella, Maria Gabriella Caporaso, Luigi Michele Pavone, Massimo D'Agostino · 2022 · Open Biology
  57. SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages
    Bo Shi, Qi-Quan Huang, Robert Birkett, Renee Doyle, Andrea Dorfleutner, Christian Stehlik, Congcong He, Richard M. Pope · 2016 · Autophagy
  58. The Endosomal Network: Mediators and Regulators of Endosome Maturation
    Maria Podinovskaia, Anne Spang · 2018 · Progress in molecular and subcellular biology
  59. P2X4 and lysosome fusion
    Ruth D. Murrell‐Lagnado, Manfred Frick · 2019 · Current Opinion in Pharmacology
  60. Physiopathological roles of vesicular nucleotide transporter (VNUT), an essential component for vesicular ATP release
    Nao Hasuzawa, Sawako Moriyama, Yoshinori Moriyama, Masatoshi Nomura · 2020 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  61. The small G protein Arl8 contributes to lysosomal function and long-range axonal transport in Drosophila
    Cláudia Rosa-Ferreira, Sean T. Sweeney, Sean Munro · 2018 · Biology Open
  62. Targeting Cancer Lysosomes with Good Old Cationic Amphiphilic Drugs
    Anne‐Marie Ellegaard, Peter Brian Bach, Marja Jäättelä · 2020 · Reviews of physiology, biochemistry and pharmacology
  63. Tubular lysosomes harbor active ion gradients and poise macrophages for phagocytosis
    Bhavyashree Suresh, Anand Saminathan, Kasturi Chakraborty, Matthew A. Zajac, Chang Cui, Lev Becker, Yamuna Krishnan · 2021 · Proceedings of the National Academy of Sciences
  64. Pharmacologically induced endolysosomal cholesterol imbalance through clinically licensed drugs itraconazole and fluoxetine impairs Ebola virus infection in vitro
    Susann Kummer, Angelika Lander, Jonas Goretzko, Norman Kirchoff, Ursula Rescher, Sebastian Schloer · 2021 · Emerging Microbes & Infections
  65. Lysosomes in Cancer—At the Crossroad of Good and Evil
    Ida Eriksson, Karin M. Öllinger · 2024 · Cells
  66. TMEM 55B contributes to lysosomal homeostasis and amino acid–induced mTORC 1 activation
    Yutaka Hashimoto, Michiko Shirane, Keiichi I. Nakayama · 2018 · Genes to Cells
  67. Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation
    Huihui Li, Zak Doric, Amandine Berthet, Danielle M. Jorgens, Mai K. Nguyen, Ivy Hsieh, Julia Margulis, Rebecca Fang, Jayanta Debnath, Hiromi Sesaki et al. · 2021 · Science Advances
  68. GPN does not release lysosomal Ca2+ but evokes Ca2+ release from the ER by increasing the cytosolic pH independently of cathepsin C
    Peace Atakpa‐Adaji, Laura M. van Marrewijk, Michael Apta-Smith, Sumita Chakraborty, Colin W. Taylor · 2019 · Journal of Cell Science
  69. The Role of Beclin-1 Acetylation on Autophagic Flux in Alzheimer’s Disease
    A. Raquel Esteves, Filipa Filipe, João Duarte Magalhães, Diana Filipa Silva, Sandra M. Cardoso · 2019 · Molecular Neurobiology
  70. HIV-1 gp120 Promotes Lysosomal Exocytosis in Human Schwann Cells
    Gaurav Datta, Nicole M. Miller, Z. Afghah, J. Geiger, Xue-Song Chen · 2019 · Frontiers in Cellular Neuroscience
  71. HIV-1 gp120-Induced Endolysosome de-Acidification Leads to Efflux of Endolysosome Iron, and Increases in Mitochondrial Iron and Reactive Oxygen Species
    Peter W. Halcrow, Koffi L. Lakpa, Nabab Khan, Zahra Afghah, Nicole Miller, Gaurav Datta, Xuesong Chen, Jonathan D. Geiger · 2021 · Journal of Neuroimmune Pharmacology
  72. Loss of the cytostome-cytopharynx and endocytic ability are late events in Trypanosoma cruzi metacyclogenesis
    Juliana Cunha Vidal, Carolina de Lima Alcantara, Wanderley de Souza, Narcisa L. Cunha‐e‐Silva · 2016 · Journal of Structural Biology
  73. HIV-1 enhances mTORC1 activity and repositions lysosomes to the periphery by co-opting Rag GTPases
    Alessandro Cinti, Valerie Le Sage, Miroslav P. Milev, Fernando Valiente‐Echeverría, Christina Crossie, Marie-Joëlle Miron, Nelly Panté, Martin Olivier, Andrew J. Mouland · 2017 · Scientific Reports
  74. The endolysosomal system in conventional and unconventional protein secretion
    Éloïse Néel, Marioara Chiritoiu‐Butnaru, William Fargues, Morgane Denus, Maëlle Colladant, Aurore Filaquier, Sarah E. Stewart, Sylvain Lehmann, Chiara Zurzolo, David Chaim Rubinsztein et al. · 2024 · The Journal of Cell Biology
  75. Role of lipids in interorganelle communication
    Neuza S. Domingues, Joana Pires, Ira Milošević, Nuno Raimundo · 2024 · Trends in Cell Biology
  76. Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity
    Yu, Yong, Gao, Shihong M, Guan, Youchen, Hu, Pei-Wen, Zhang, Qinghao, Liu, Jiaming, Jing, Bentian, Zhao, Qian, Sabatini, David M, Abu-Remaileh, Monther et al. · 2024 · eLife
  77. A pH‐Responsive Nanoparticle Library with Precise pH Tunability by Co‐Polymerization with Non‐Ionizable Monomers
    Ruiyang Zhao, Chuanxun Fu, Zenghui Wang, Meijie Pan, Bin Ma, Qingqing Yin, Binlong Chen, Jianxiong Liu, Heming Xia, Fangjie Wan et al. · 2022 · Angewandte Chemie International Edition
  78. The where, what, and when of membrane protein degradation in neurons
    Eugene Jennifer Jin, Ferdi Rıdvan Kiral, P. Robin Hiesinger · 2017 · Developmental Neurobiology
  79. The lysosomal disease caused by mutant VPS33A
    Elena Pavlova, Aleksey Shatunov, Lena Wartosch, Alena I Moskvina, Lena E Nikolaeva, Nicholas A. Bright, Karen L. Tylee, Heather J. Church, Andrea Ballabio, J. Paul Luzio et al. · 2019 · Human Molecular Genetics
  80. Monitoring autophagy in cancer: From bench to bedside
    Maeve Long, Thomas G. McWilliams · 2019 · Seminars in Cancer Biology
  81. Fluorescence Lifetime Imaging of pH along the Secretory Pathway
    Peter T. A. Linders, Melina Ioannidis, Martin ter Beest, Geert van den Bogaart · 2022 · ACS Chemical Biology
  82. Survival strategies of cancer cells: the role of macropinocytosis in nutrient acquisition, metabolic reprogramming, and therapeutic targeting
    Guoshuai Xu, Qinghong Zhang, Renjia Cheng, Jun Qu, Wenqiang Li · 2025 · Autophagy
  83. Quantitative imaging of membrane contact sites for sterol transfer between endo-lysosomes and mitochondria in living cells
    Alice Dupont Juhl, Christian W. Heegaard, Stephan Werner, Gerd Schneider, Kathiresan Krishnan, Douglas F. Covey, Daniel Wüstner · 2021 · Scientific Reports
  84. β-Cell autophagy in the pathogenesis of type 1 diabetes
    Charanya Muralidharan, Amelia K. Linnemann · 2021 · American Journal of Physiology-Endocrinology and Metabolism
  85. Roads and hubs of unconventional protein secretion
    Aurore Filaquier, Philippe Marin, Marie‐Laure Parmentier, Julien Villeneuve · 2022 · Current Opinion in Cell Biology
  86. Detection and quantification of the vacuolar H+ATPase using the Legionella effector protein SidK
    Michelle E. Maxson, Yazan M. Abbas, Jing Wu, Jonathan D. Plumb, Sergio Grinstein, John L. Rubinstein · 2021 · The Journal of Cell Biology
  87. Mutational Analysis of Lassa Virus Glycoprotein Highlights Regions Required for Alpha-Dystroglycan Utilization
    Marissa Danielle Acciani, Jacob T. Alston, Guohui Zhao, Hayley M. Reynolds, Afroze M. Ali, Brian Xu, Melinda Ann Brindley · 2017 · Journal of Virology
  88. Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy
    Philip E.D. Chung, Deena M.A. Gendoo, Ronak Ghanbari-Azarnier, Jeff C. Liu, Zhe Jiang, Jennifer Tsui, Dong‐Yu Wang, Xiao Xiao, Bryan K. Li, Adrian M. Dubuc et al. · 2020 · Nature Communications
  89. DRAM1 plays a tumor suppressor role in NSCLC cells by promoting lysosomal degradation of EGFR
    Ji Geng, Rong Zhang, Xiao Yuan, Haidong Xu, Zhou Zhu, Xinxin Wang, Yan Wang, Guoqiang Xu, Wenjie Guo, Junchao Wu et al. · 2020 · Cell Death and Disease
  90. Distinct retrograde microtubule motor sets drive early and late endosome transport
    Giulia Villari, Chiara Enrico Bena, Marco Del Giudice, Noemi Gioelli, Chiara Sandri, Chiara Camillo, Alessandra Fiorio, Carla Bosia, Guido Serini · 2020 · The EMBO Journal
  91. The journey of Ca2+ through the cell – pulsing through the network of ER membrane contact sites
    Tom Cremer, Jacques Neefjes, Ilana Berlin · 2020 · Journal of Cell Science
  92. Lysosomal ion channels involved in cellular entry and uncoating of enveloped viruses: Implications for therapeutic strategies against SARS-CoV-2
    Zhuangzhuang Zhao, Pan Qin, Yao‐Wei Huang · 2021 · Cell Calcium
  93. Lysosomes in acute myeloid leukemia: potential therapeutic targets?
    Sreoshee Rafiq, Sharon L. McKenna, Sylviane Muller, Mario P. Tschan, Magali Humbert · 2021 · Leukemia
  94. ClC-7 drives intraphagosomal chloride accumulation to support hydrolase activity and phagosome resolution
    Jing Wu, Mariia Zeziulia, Whijin Kwon, Thomas J. Jentsch, Sergio Grinstein, Spencer A. Freeman · 2023 · The Journal of Cell Biology
  95. Deacidification of endolysosomes by neuronal aging drives synapse loss
    Burrinha, Tatiana, Cunha, César, Hall, Michael J., Lopes‐da‐Silva, Mafalda, Seabra, Miguel C., Guimas Almeida, Cláudia · 2023 · Traffic
  96. Quantitative Proteome Analysis of Mouse Liver Lysosomes Provides Evidence for Mannose 6-phosphate-independent Targeting Mechanisms of Acid Hydrolases in Mucolipidosis II
    Sandra Markmann, Svenja Krambeck, Christopher J. Hughes, Mina Mirzaian, Johannes M. F. G. Aerts, Paul Säftig, Michaela Schweizer, Johannes P.C. Vissers, Thomas Braulke, Markus Daμμe · 2017 · Molecular & Cellular Proteomics
  97. Energetic adaptations: Metabolic control of endocytic membrane traffic
    Sadia Rahmani, Marina S. Defferrari, Warren W. Wakarchuk, Costin N. Antonescu · 2019 · Traffic
  98. A modified lysosomal organelle mediates nonlytic egress of reovirus
    Isabel Fernández de Castro, Raquel Tenorio, Paula Ortega-González, Jonathan J. Knowlton, Paula F. Zamora, Christopher H. Lee, José‐Jesús Fernández, Terence S. Dermody, Cristina Risco · 2020 · The Journal of Cell Biology
  99. From the inside out: Ion fluxes at the centre of endocytic traffic
    Sarah R. Chadwick, Sergio Grinstein, Spencer A. Freeman · 2021 · Current Opinion in Cell Biology
  100. Inhibition of Transient Receptor Potential Channel Mucolipin-1 (TRPML1) by Lysosomal Adenosine Involved in Severe Combined Immunodeficiency Diseases
    Xi Zoë Zhong, Yuanjie Zou, Xue Jun Sun, Gaofeng Dong, Qi Cao, Aditya Nath Pandey, Jan K. Rainey, Xiaojuan Zhu, Xian‐Ping Dong · 2017 · Journal of Biological Chemistry