The position of lysosomes within the cell determines their luminal pH
Johnson, Danielle E., Ostrowski, Philip, Jaumouillé, Valentin, Grinstein, Sergio·2016·Journal of Cell Biology
Cited by (591)
Items 301–400 of 591
- Kushenol E inhibits autophagy and impairs lysosomal positioning via VCP/p97 inhibitionMincheol Kwon, Mina Jang, Gun-Hee Kim, Taehoon Oh, In‐Ja Ryoo, Hyung Won Ryu, Sei‐Ryang Oh, Bo Yeon Kim, Jae‐Hyuk Jang, Sung‐Kyun Ko et al. · 2020 · Biochemical Pharmacology
- Branching Off: New Insight Into Lysosomes as Tubular OrganellesK. Adam Bohnert, Alyssa E. Johnson · 2022 · Frontiers in Cell and Developmental Biology
- The Multidirectional Effect of Azelastine Hydrochloride on Cervical Cancer CellsEwa Trybus, Teodora Król, Wojciech Trybus · 2022 · International Journal of Molecular Sciences
- Secretion of VGF relies on the interplay between LRRK2 and post-Golgi v-SNAREsFrancesca Filippini, Sébastien Nola, Ahmed Zahraoui, Kévin Roger, Mansoore Esmaili, Ji Sun, José Wojnacki, Anaïs Vlieghe, Philippe Bun, Stéphanie Blanchon et al. · 2023 · Cell Reports
- Arf1-PI4KIIIβ positive vesicles regulate PI(3)P signaling to facilitate lysosomal tubule fissionMaxime Boutry, Laura F. DiGiovanni, Nicholas D. Demers, Aaron Fountain, Sami Mamand, Roberto J. Botelho, Peter Kijun Kim · 2023 · The Journal of Cell Biology
- NUAK1 coordinates growth factor-dependent activation of mTORC2 and Akt signalingMario Palma, Elizabeth N. Riffo, Alejandro Farías, Viviana Coliboro-Dannich, Luis Espinoza-Francine, Emilia Escalona, Roberto Amigo, José Leonardo Gutiérrez, Roxana Pincheira, Ariel Fernando Castro · 2023 · Cell & Bioscience
- INPP4B promotes PDAC aggressiveness via PIKfyve and TRPML-1–mediated lysosomal exocytosisGolam T. Saffi, Lydia To, Nicholas Kleine, Ché M.P. Melo, K Chen, Gizem Esra Genç, K.C. Daniel Lee, Jonathan Tak-Sum Chow, Gun Ho Jang, Steve Gallinger et al. · 2024 · The Journal of Cell Biology
- Autophagy, lysosome dysfunction and mTOR inhibition in MNU-induced photoreceptor cell damageYing Li, Chenguang Wang, Yang Liu, Jiaxin You, Guanfang Su · 2019 · Tissue and Cell
- A guide to measuring phagosomal dynamicsRoni Levin‐Konigsberg, Adriana R. Mantegazza · 2020 · FEBS Journal
- Extracellular Acidification Induces Lysosomal DysregulationBryce Ordway, Robert J. Gillies, Mehdi Damaghi · 2021 · Cells
- Garcinone E Blocks Autophagy Through Lysosomal Functional Destruction in Ovarian Cancer CellsXiao-Huang Xu, Yu‐Chi Chen, Yu-Lian Xu, Zheling Feng, Qian-Yu Liu, Xia Guo, Li-Gen Lin, Jin-Jian Lu · 2021 · World Journal of Traditional Chinese Medicine
- Nuclear ingression of cytoplasmic bodies accompanies a boost in autophagyManon Garcia, Sylvain Kumanski, Alberto Elías-Villalobos, Chantal Cazevieille, Caroline Soulet, María Moriel‐Carretero · 2022 · Life Science Alliance
- Cellular vacuolization caused by overexpression of the PIKfyve-binding deficient Vac14L156R is rescued by starvation and inhibition of vacuolar-ATPaseUlf Schulze, Beate Vollenbröker, Alexander Kühnl, Daniel Granado, Samet Bayraktar, Ursula Rescher, Hermann Pavenstädt, Thomas Weide · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Dynamic organization of intracellular organelle networksWenjing Li, Shuhao Zhang, Ge Yang · 2020 · WIREs Mechanisms of Disease
- A novel aptamer-based small RNA delivery platform and its application to cancer therapyToshihiko Tanno, Peng Zhang, Christopher M. Bailey, Yin Wang, Wannaporn Ittiprasert, Martin Devenport, Pan Zheng, Yang Liu · 2022 · Genes & Diseases
- Endosomal sorting sorted – motors, adaptors and lessons from in vitro and cellular studiesGregory Redpath, Vaishnavi Ananthanarayanan · 2023 · Journal of Cell Science
- Multiparameter Assessment of Foam Cell Formation Progression Using a Dual-Color Switchable Fluorescence ProbeZi-Lu Li, Gui‐Mei Han, Kun Wang, Jia-Ao Lyu, Ziwen Li, Baocun Zhu, Li−Na Zhu, De‐Ming Kong · 2024 · Analytical Chemistry
- MYO18B promotes lysosomal exocytosis by facilitating focal adhesion maturationWeiwei Ren, Rebeca Kawahara, Kenichi G. N. Suzuki, Priya Dipta, Ganglong Yang, Morten Thaysen‐Andersen, Morihisa Fujita · 2024 · The Journal of Cell Biology
- Lysosomal dysfunction of corneal fibroblasts underlies the pathogenesis of Granular Corneal Dystrophy Type 2 and can be rescued by TFEBSeung‐il Choi, Jong Hwan Woo, Eung Kweon Kim · 2020 · Journal of Cellular and Molecular Medicine
- In vitro cytotoxicity study of superparamagnetic iron oxide and silica nanoparticles on pneumocyte organellesA. Solorio-Rodríguez, Vicente Escamilla‐Rivera, M. Uribe-Ramírez, Sirenia González‐Pozos, J. Hernández-Soto, Leticia Rafael-Vázquez, Andrea De Vizcaya‐Ruíz · 2020 · Toxicology in Vitro
- Maturing Autophagosomes are Transported Towards the Cell PeripheryAnna Maria Hilverling, Éva M. Szegő, Elisabeth Dinter, Diana Cozma, Theodora Saridaki, Björn H. Falkenburger · 2021 · Cellular and Molecular Neurobiology
- P2X7 Receptor Triggers Lysosomal Leakage Through Calcium Mobilization in a Mechanism Dependent on Pannexin-1 HemichannelsStephanie Alexia Cristina Silva Santos, Pedro Muanis Persechini, Bianca Monteiro Henriques‐Santos, Victória Gabriela Bello-Santos, Newton Gonçalves Castro, Júlia Costa de Sousa, Fernando Ariel Genta, Marcelo F. Santiago, Robson Coutinho‐Silva, Luiz Eduardo Baggio Savio et al. · 2022 · Frontiers in Immunology
- The Autophagy Receptor TAX1BP1 (T6BP) improves antigen presentation by MHC‐II moleculesGabriela Sarango, Clémence Richetta, Mathias Pereira, Anita Kumari, Michael Ghosh, Lisa Bertrand, Cédric Pionneau, Morgane Le Gall, Sylvie Grégoire, Raphaël Jeger‐Madiot et al. · 2022 · EMBO Reports
- How crosstalk between mitochondria, lysosomes, and other organelles can prevent or promote dry age-related macular degenerationAparna Lakkaraju, Patricia Boya, MARIE E. CSETE, Deborah A. Ferrington, James B. Hurley, Alfredo Arrigo Sadun, Peng Shang, Ruchi Sharma, Debasish Sinha, Marius Ueffing et al. · 2024 · Experimental Eye Research
- Subcellular distribution of Prussian blue nanozymes dictates enzymatic activity and macrophage polarization for effective colitis therapyHe Ding, Mengmeng Long, Yuehuang Wu, Yuxin Zhang, Zhenyu Yang, Xianwu Yan, Yan Li, Yan Shen, Miao Zhang, Yunjiao Zhang et al. · 2025 · Biomaterials
- TMEM175 does not function as a proton-selective ion channel to prevent lysosomal over-acidificationErika A. Riederer, Vedrana Mikušević, Tuoxian Tang, Lillian Martin, Joseph A. Mindell, Dejian Ren · 2025 · The Journal of Cell Biology
- Cell viability assay as a tool to study activity and inhibition of hepatitis C p7 channelsUlrike Breitinger, Noha Samir Farag, Nourhan K. M. Ali, Marwa Ahmed, Mohamed El-Azizi, Hans‐Georg Breitinger · 2021 · Journal of General Virology
- Measurement of Lysosome Positioning by Shell Analysis and Line ScanChad D. Williamson, Carlos M. A. Guardia, Raffaella De Pace, Juan S. Bonifacino, Amra Sarić · 2022 · Methods in molecular biology
- Lysosomal Function and Intracellular Position Determine the Malignant Phenotype in Malignant MelanomaIda Eriksson, Linda K. Vainikka, Petra Wäster, Karin M. Öllinger · 2023 · Journal of Investigative Dermatology
- Luminescence Fingerprint of Intracellular NIR-II Gold Nanocluster Transformation: Implications for Sensing and ImagingMarina París Ogáyar, Zeineb Ayed, Véronique Josserand, Maxime Henry, Álvaro Artiga, Livia Didonè, Miriam Granado, Aída Serrano, Ana Espinosa, Xavier Le Guével et al. · 2025 · ACS Nano
- The big and intricate dreams of little organelles: Embracing complexity in the study of membrane trafficAllen P. Liu, Roberto J. Botelho, Costin N. Antonescu · 2017 · Traffic
- Activity-independent targeting of mTOR to lysosomes in primary osteoclastsAndrew Wang, Luciene Regina Carraro‐Lacroix, Celeste Owen, Bowen Gao, Paul Corey, Pascal N. Tyrrell, John Hunter Brumell, Irina Voronov · 2017 · Scientific Reports
- Deregulation of signalling in genetic conditions affecting the lysosomal metabolism of cholesterol and galactosyl-sphingolipidsSwetha Gowrishankar, Stephanie M. Cologna, Maria Irene Givogri, Ernesto Roque Bongarzone · 2020 · Neurobiology of Disease
- P2X4 Receptors Mediate Ca2+ Release from Lysosomes in Response to Stimulation of P2X7 and H1 Histamine ReceptorsSin Lih Tan, Muruj Barri, Peace Atakpa‐Adaji, Colin W. Taylor, Ewan St. John Smith, Ruth D. Murrell‐Lagnado · 2021 · International Journal of Molecular Sciences
- Glutamine Produces Ammonium to Tune Lysosomal pH and Regulate Lysosomal FunctionJian Xiong, Thi Thu Trang Luu, Kartik Venkatachalam, Guangwei Du, Michael X. Zhu · 2022 · Cells
- Analysis of Radachlorin localization in living cells by fluorescence lifetime imaging microscopyAndrey V. Belashov, Anna A. Zhikhoreva, Anna V. Salova, Tatiana N. Belyaeva, Ilia K. Litvinov, Е. С. Корнилова, Irina V. Semenova, Oleg S. Vasyutinskii · 2023 · Journal of Photochemistry and Photobiology B Biology
- COVID-19: the CaMKII-like system of S protein drives membrane fusion and induces syncytial multinucleated giant cellsWenzhong Liu, Li hualan · 2021 · Immunologic Research
- Organelle morphology and positioning orchestrate physiological and disease-associated processesKateřina Jeřábková, Rituraj Marwaha, Tamal Das, Jacky G. Goetz · 2023 · Current Opinion in Cell Biology
- Two-pore channels regulate endomembrane tension to enable remodeling and resolution of phagolysosomesSarah R. Chadwick, Dante Barreda, Jing Wu, Gang Ye, Bushra Yusuf, Dejian Ren, Spencer A. Freeman · 2024 · Proceedings of the National Academy of Sciences
- Lysosome-targeting pH indicator based on peri-fused naphthalene monoimide with superior stability for long term live cell imagingAstrid Tannert, Javier García López, Nikolay Petkov, Anela Ivanova, Kalina Peneva, Ute Neugebauer · 2020 · Journal of Materials Chemistry B
- Biogenesis of Exosomes Laden with Metallic Silver–Copper Nanoparticles Liaised by Wheat Germ Agglutinin for Targeted Delivery of Therapeutics to Breast CancerSarmadia Ashraf, Shahnaz Majid Qadri, Shayista Akbar, Aijaz Parray, Yousef Haik · 2022 · Advanced Biology
- Protons in small spaces: Discrete simulations of vesicle acidificationApeksha Singh, Frank V. Marcoline, Salome Veshaguri, Aimee W. Kao, Marcel P. Bruchez, Joseph A. Mindell, Dimitrios G. Stamou, Michael Grabe · 2019 · PLoS Computational Biology
- Disruption of the Rab7-Dependent Final Common Pathway of Endosomal and Autophagic Processing Results in a Severe PodocytopathyKristin Vöing, Ulf Michgehl, Nils David Mertens, Cara Picciotto, Mee-Ling Maywald, Jonas Goretzko, Sofie Waimann, Kevin Gilhaus, Manuel Rogg, Christoph Schell et al. · 2023 · Journal of the American Society of Nephrology
- Copper‐independent lysosomal localisation of the Wilson disease protein ATP7BSaptarshi Maji, Marinella Pirozzi, Ruturaj, Raviranjan Pandey, Tamal Ghosh, Santanu Das, Arnab Gupta · 2023 · Traffic
- A zinc metal complex as an NIR emissive probe for real-time dynamics and in vivo embryogenic evolution of lysosomes using super-resolution microscopyAbdul Salam, Kush Kaushik, Bodhidipra Mukherjee, Farhan Anjum, Goraksha T. Sapkal, Shagun Sharma, Richa Garg, Chayan Kanti Nandi · 2024 · Chemical Science
- Rab20 is critical for bacterial lipoprotein tolerization-enhanced bactericidal activity in macrophages during bacterial infectionShuqi Zhao, Dalin Xi, Junwei Cai, Wenting Chen, Jing Xiang, Na Peng, Juan Wang, Yong Jiang, Zhu-Zhong Mei, Jinghua Liu · 2019 · Science China Life Sciences
- Can endolysosomal deacidification and inhibition of autophagy prevent severe COVID-19?Gerwyn Morris, Eugene Athan, Ken R. Walder, Chiara C. Bortolasci, Adrienne E O'Neil, Wolfgang Marx, Michael Berk, Andre Ferrer Carvalho, Michael H. J. Maes, Basant K. Puri · 2020 · Life Sciences
- Diverse cellular strategies for the export of leaderless proteinsJianfei Zheng, Liang Ge · 2022 · National Science Open
- DNA nanodevices detect an acidic nanolayer on the lysosomal surfaceYutong Zhang, Hu Meiqin, Yaping Meng, Xin Wang, Fangqian Huang, Ping Li, Yuting Zhuo, Danzhen Chen, Zhimin Wang, Qiang Zhang et al. · 2026 · Nature Cell Biology
- Disrupted endoplasmic reticulum-mediated autophagosomal biogenesis in a Drosophila model of C9-ALS-FTDHyun Sung, Thomas E. Lloyd · 2023 · Autophagy
- RETRACTED: Lysosomes in Stem Cell Quiescence: A Potential Therapeutic Target in Acute Myeloid LeukemiaVaibhav Jain, Swaroop N. Bose, Awadhesh Kumar Arya, Tasleem Arif · 2022 · Cancers · Retracted
- The critical role of the endolysosomal system in cerebral ischemiaYing Xu, Huiyi Zhang, Ye Tian, Han-Yan Shi, Ya Cai · 2022 · Neural Regeneration Research
- Oxidized cholesteryl ester induces exocytosis of dysfunctional lysosomes in lipidotic macrophagesNeuza S. Domingues, André R. A. Marques, Rita Diogo Almeida Calado, Inês S. Ferreira, Cristiano Ramos, José C. Ramalho, Maria I. L. Soares, Telmo Pereira, Luís Oliveira, José R. Vicente et al. · 2023 · Traffic
- Quantification of Efferocytosis by Single-cell Fluorescence MicroscopyKyle Taruc, Charles Yin, Dan Gower Wootton, Bryan Heit · 2018 · Journal of Visualized Experiments
- Sonochemical Formation of Copper/Iron‐Modified Graphene Oxide Nanocomposites for Ketorolac DeliveryDarya V. Radziuk, Lubov Mikhnavets, Mykhailo Vorokhta, Vladimı́r Matolín, Л. В. Табулина, В. А. Лабунов · 2019 · Chemistry - A European Journal
- Rab GTPases in the differential processing of phagocytosed pathogens versus efferocytosed apoptotic cells.Nima Taefehshokr, Charles Yin, Bryan Heit · 2021 · PubMed
- Mitochondria-lysosome coupling contributes to lysosome acidification and agingQingqing Liu, Seungmin Yoo, Zhixin A. Zhang, Liying Li, Hetian Su, Lingraj Vannur, Alexandra C Wooldredge, Jun‐Wei B. Hughes, Pierre-Yves Desprez, Nan Hao et al. · 2026 · Molecular Cell
- Pathological Functions of Lysosomal Ion Channels in the Central Nervous SystemJian-Ke Cen, Nan Hu, Jiawen Shen, Yong‐Jing Gao, Huan-Jun Lu · 2024 · International Journal of Molecular Sciences
- Shining a Light on Black Holes in KeratinocytesShanna L. Bowman, Michael S. Marks · 2018 · Journal of Investigative Dermatology
- Mitochondria targeted self-assembled ratiometric fluorescent nanoprobes for pH imaging in living cellsZhenzhen Feng, Yanyun Ma, Bingjie Li, Leiliang He, Qing Wang, Jin Lin Huang, Jianbo Liu, Xiaohai Yang, Kemin Wang · 2019 · Analytical Methods
- Pan-cellular organelles and suborganelles—from common functions to cellular diversity?Rico Schieweck, Magdalena Götz · 2024 · Genes & Development
- Tetrahedral DNA-Based Ternary Recognition Ratiometric Fluorescent Probes for Real-Time In Situ Resolving Lysosome Subpopulations in Living Cells via Cl–, Ca2+, and pHGuang-Yue Zou, Fan Bi, Yong‐Liang Yu, Meng-Xian Liu, Shuai Chen · 2024 · Analytical Chemistry
- Nano-bio-encapsulation of phyto-vaccines: a breakthrough in targeted cancer immunotherapyPavithra Ayyadurai, Chinnasamy Ragavendran · 2024 · Molecular Biology Reports
- Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological FunctionsShanshan Jiang, Jingyi Fu, Shan Li, Zehui Li, Qirui Zhao, Yuqi Yin, Mei Yang, Yonghua Wang · 2025 · Traffic
- Lysosome pH Dynamics in Physiology and Disease: Molecular Mechanisms and Therapeutic InsightsSonia Infante-Tadeo, Diane L. Barber · 2026 · Acta Physiologica
- Cellular transport of uranium and its cytotoxicity effects on CHO-k1 cellsLiqun Huang, Shufang Li, Wenhua Zhou, Jie Gao, Jingjing Yin, Zhongwen Wang, Jianguo Li · 2022 · Ecotoxicology and Environmental Safety
- BORC complex specific components and Kinesin-1 mediate autophagy evasion by the autophagy-resistant Mycobacterium tuberculosis Beijing strainJanpen Tunganuntarat, Phongthon Kanjanasirirat, Tanawadee Khumpanied, Salisa Benjaskulluecha, Benjawan Wongprom, Tanapat Palaga, Tegar Adriansyah Putra Siregar, Suparerk Borwornpinyo, Angkana Chaiprasert, Prasit Palittapongarnpim et al. · 2023 · Scientific Reports
- Opioid Modulation of Neuronal Iron and Potential Contributions to NeuroHIVBradley Nash, Elena Irollo, Renato Brandimarti, Olimpia Meucci · 2020 · Methods in molecular biology
- Endosomes supporting fusion mediated by vesicular stomatitis virus glycoprotein have distinctive motion and acidificationMaya Cabot, Volker Kiessling, Judith M. White, Lukas K. Tamm · 2022 · Traffic
- Folliculin – A tumor suppressor at the intersection of metabolic signaling and membrane trafficDodding, Mark P. · 2017 · Small GTPases
- Septin-coated microtubules promote maturation of multivesicular bodies by inhibiting their motilityBenjamin P. Robinson, Naomi R. Bass, Priyanka Bhakt, Elias T. Spiliotis · 2024 · The Journal of Cell Biology
- Quantitative profiling pH heterogeneity of acidic endolysosomal compartments using fluorescence lifetime imaging microscopyDinghuan Deng, Youchen Guan, Ayse Sena Mutlu, Baiping Wang, Shihong Max Gao, Hui Zheng, Meng Carla Wang · 2025 · Molecular Biology of the Cell
- Reprogramming of endolysosomes for melanogenesis in BLOC-1-deficient melanocytesPhilip S. Goff, Shyamal Patel, Dawn C. Harper, Tom D. Carter, Michael S. Marks, Elena V. Sviderskaya · 2025 · Current Biology
- Mitochondrial respiratory chain regulates HBV clearance through dual modulation of lysosomal acidificationZhiqiang Wei, Yanying Yan, Lingzhu Zhao, Chen Li, Jinjin Qi, Dandan Chen, Xiuzhen Huang, Minwei Li, Zhengyun Xiao, Guohua Lou et al. · 2025 · Emerging Microbes & Infections
- Maintenance and Decline of Neuronal Lysosomal Function in AgingRuiling Zhong, Claire E. Richardson · 2025 · Cells
- Endolysosomal vesicles at the center of B cell activationSaara Hämälistö, Felipe Del Valle Batalla, María-Isabel Yuseff, Pieta K. Mattila · 2024 · The Journal of Cell Biology
- Improvement of Production and Isolation of Human Neuraminidase-1 in Cellulo CrystalsKotaro Koiwai, Jun Tsukimoto, Tetsuya Higashi, Fumitaka Mafuné, Ken Miyajima, Takanori Nakane, Naohiro Matsugaki, Ryuichi Kato, Serena Sirigu, Arjen J. Jakobi et al. · 2019 · ACS Applied Bio Materials
- Accelerated Clearance and Degradation of Cell-Free HIV by Neutralizing Antibodies Occurs via FcγRIIb on Liver Sinusoidal Endothelial Cells by EndocytosisJames M. Turman, Alana M. Cheplowitz, Charu Tiwari, Thushara Thomas, Dhruvi Kalpesh Joshi, Menakshi Bhat, Qian Wu, Erik Pong, Seung Y. Chu, David E. Szymkowski et al. · 2021 · The Journal of Immunology
- Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamicsRainer Ettelt, Ana-Maria Șandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas Alfons Huber, Manuela Baccarini · 2026 · FEBS Letters
- LAMP-1-chimeric DNA vaccines enhance the antibody response in Japanese flounder, Paralichthys olivaceusIang Schroniltgen Rondón‐Barragán, Reiko Nozaki, Ikuo Hırono, Hidehiro Kondo · 2017 · Fish & Shellfish Immunology
- Acidic Compartment Size, Positioning, and Function during Myogenesis and Their Modulation by the Wnt/Beta‐Catenin PathwayKayo Moreira Bagri, Ivone de Andrade Rosa, Stephany Corrêa, Aline Yamashita, José M. Brito, Flávia Fonseca Bloise, Manoel Luís Costa, Cláudia Mermelstein · 2020 · BioMed Research International
- Lysosomal physiology and pancreatic lysosomal stress in diabetes mellitusMeihua Hao, S. Sebag, Qingwen Qian, Ling Yang · 2024 · eGastroenterology
- Neurofilament accumulation disrupts autophagy in giant axonal neuropathyJean‐Michel Paumier, James P. Zewe, Chiranjit Panja, Melissa R. Pergande, Meghana Venkatesan, Eitan Israeli, Shikha Prasad, Natasha Tasheva Snider, Jeffrey N. Savas, Puneet Opal · 2025 · JCI Insight
- A novel miniaturized filamentous phagemid as a gene delivery vehicle to target mammalian cellsShirley Lau Wong, Salma Jimenez, Deborah Pushparajah, Rohini Prakash, Roderick Adrian Slavcev · 2025 · Molecular Therapy — Nucleic Acids
- Inactive ryanodine receptors sustain lysosomal availability for autophagy by promoting ER-lysosomal contact site formationTim Vervliet, Jens Loncke, Marko Sever, Karan Ahuja, Chris Van den Haute, Tomas Luyten, Grace E. Stutzmann, Catherine M. Verfaillie, Tihomir Tomašič, Geert Bultynck · 2026 · Nature Communications
- Biogenesis of specialized lysosomes in differentiated keratinocytes relies on close apposition with the Golgi apparatusSarmistha Mahanty, Ptissam Bergam, Vivek Belapurkar, Litralson Eluvathingal, Nikita Gupta, Bruno Goud, Deepak Kumar Nair, Graça Raposo, Subba Rao Gangi Setty · 2024 · Cell Death and Disease
- RNF13 mediates pH- and Ca2+-dependent regulation of lysosomal positioningTrinh, Lan Thi, Van Vu, Anh, Shin, Seunghye, Lee, Chanhaeng, Park, Sang-Hee, Cho, Eun-Bee, Heo, Yunseok, Kim, Hyun Jin, Kim, Sungjoo, Yoon, Jong-Bok · 2025 · Cell Reports
- A homozygous hypomorphicBNIP1variant causes an increase in autophagosomes and reduced autophagic flux and results in a spondylo‐epiphyseal dysplasiaTess Holling, Gandham SriLakshmi Bhavani, Leonie von Elsner, Hitesh Hasmukhlal Shah, Neethukrishna Kausthubham, Shaila S. Bhattacharyya, Anju Shukla, Geert R. Mortier, Thorsten Schinke, Tatyana Danyukova et al. · 2022 · Human Mutation
- Down Syndrome Fetal Fibroblasts Display Alterations of Endosomal Trafficking Possibly due to SYNJ1 OverexpressionLaura De Rosa, D Fasano, Lucrezia Zerillo, Valeria Valente, Antonella Izzo, Nunzia Mollo, Giuseppina Amodio, Elena Polishchuk, Roman Polishchuk, Mariarosa Anna Beatrice Melone et al. · 2022 · Frontiers in Genetics
- Microtubule acetylation induced by oxidative stress regulates subcellular distribution of lysosomal vesicles for amyloid‐beta secretionJangho Jeong, Ok‐Hyeon Kim, Jaeyeoung Shim, Seula Keum, Ye Eun Hwang, Seongeun Song, Jung‐Woong Kim, Jee‐Hye Choi, Hyun Jung Lee, Sangmyung Rhee · 2023 · Journal of Cellular Physiology
- Measuring pH of the Coxiella burnetii Parasitophorous VacuoleDhritiman Samanta, Stacey D. Gilk · 2017 · Current Protocols in Microbiology
- Changes in endolysosomal organization define a pre-degenerative state in the crumbs mutant Drosophila retinaRachel Susan Kraut, Elisabeth Knust · 2019 · PLoS ONE
- Loss of KEAP1 Causes an Accumulation of Nondegradative OrganellesElisabet Uribe-Carretero, Guadalupe Martínez-Chacón, Sokhna M. S. Yakhine-Diop, Gema Duque-González, Mario Rodríguez‐Arribas, Eva Alegre-Cortés, Marta Paredes-Barquero, Saray Canales-Cortés, Elisa Pizarro‐Estrella, Antonio Cuadrado et al. · 2022 · Antioxidants
- LysosomeÚrsula da Silveira Matte, Gabriela Pasqualim · 2016 · Journal of Inborn Errors of Metabolism and Screening
- Dimethyl Fumarate Prevents HIV-Induced Lysosomal Dysfunction and Cathepsin B Release from MacrophagesLester J. Rosario-Rodríguez, Krystal Colón, Gabriel Borges-Vélez, Karla Negrón, Loyda M. Meléndez · 2018 · Journal of Neuroimmune Pharmacology
- Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidificationMuwei Jiang, Frans Bianchi, Geert van den Bogaart · 2025 · FEBS Letters
- Endoplasmic reticulum junctions serve as a platform for endosome-lysosome interactions through their stop-and-go motion switchingWenjing Li, Yuanhao Guo, Qi Wang, Mengxuan Qiu, Yudong Zhang, Yutong Yang, Junjie Hu, Ge Yang · 2025 · Science Advances
- Fundamental role of spatial positioning of Mycobacterium tuberculosis in mycobacterial survival in macrophagesShivani Sahu, Navin Baid, Deepali Aggarwal, Ankita Sharma, Manisha Gun, Sahanawaz Molla, Anunay Sinha, Ambey Prasad Dwivedi, Amit Tuli, Mahak Sharma et al. · 2025 · Nature Communications
- Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCCLina Ouologuem, Anna Kübler, Sarah Ouologuem, Amar Hadzic, Jan B. Stöckl, Anna Chiara Siciliano, Stefania Forciniti, Salvatore Lo Nigro, Helena Iuele, Valentina Onesto et al. · 2025 · Frontiers in Immunology
- Lysosome trafficking across intracellular and intercellular networks in the brainDylan T. Murphy, Chih Hung Lo · 2026 · Frontiers in Molecular Neuroscience