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EFFECTS OF MITOTIC SPINDLE INHIBITORS ON NEUROTUBULES AND NEUROFILAMENTS IN ANTERIOR HORN CELLS
Open accessAbstract
An understanding of the chemistry of the microtubule and of its in vivo response to colchicine administration has been facilitated by the recent work of Taylor and his coworkers (1, 2). Robbins and Gonatas (3) have shown that colchicine causes the breakdown of mitotic spindle tubules of HeLa cells and a simultaneous increase in the apparent number of 90-A microfilaments in the cytoplasm. Similar changes have been observed by Padawer in the mast cell. ' Finally, the homology between the spindle tubule and the neurotubule has been suggested (4). After subarachnoid injection of colchicine, there is an accumulation of filaments in the neurons of the spinal cord anterior horn (5). Similar proliferation
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Cited by
Glial Fibrillary Acidic Protein: GFAP-Thirty-One Years (1969–2000)
Eng, L. F., Ghirnikar, R. S., & Lee, Y. L. (2000) · Neurochemical Research · doi:10.1023/a:1007677003387 · Cited by 1,369
Introducing intermediate filaments: from discovery to disease
Eriksson, J. E., Dechat, T., Grin, B., Helfand, B., Mendez, M., Pallari, H.-M., & Goldman, R. D. (2009) · Journal of Clinical Investigation · doi:10.1172/jci38339 · Cited by 451
Wilson, L. (1970) · Biochemistry · doi:10.1021/bi00827a026 · Cited by 386
Aluminum in the Environment and Human Health
Sorenson, J. R. J., Campbell, I. R., Tepper, L. B., & Lingg, R. D. (1974) · Environmental Health Perspectives · doi:10.1289/ehp.7483 · Cited by 280
Metadata
- Authors
- Wisniewski, H., Shelanski, M. L., & Terry, R. D.
- Venue
- The Journal of Cell Biology
- Publisher
- Rockefeller University Press
- Published
- 1968-07-01
- Volume
- 38
- Issue
- 1
- Pages
- 224-229
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2172149249
- Cited by
- 376
- References
- 0
- FWCI
- 23.35
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: EFFECTS OF MITOTIC SPINDLE INHIBITORS ON NEUROTUBULES AND NEUROFILAMENTS IN ANTERIOR HORN CELLS. https://app.cochat.ai/papers/10.1083/jcb.38.1.224
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- Wisniewski, H., Shelanski, M. L., & Terry, R. D. (1968). EFFECTS OF MITOTIC SPINDLE INHIBITORS ON NEUROTUBULES AND NEUROFILAMENTS IN ANTERIOR HORN CELLS. The Journal of Cell Biology. https://doi.org/10.1083/jcb.38.1.224
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
