The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
PLASMA MEMBRANES OF THE RAT LIVER
Open accessAbstract
A method is described for the rapid isolation of a plasma membrane fraction containing a high concentration of intact bile canaliculi from the rat liver. Isolated bile canaliculi retain most of the ultrastructural features exhibited in the intact liver cell. The final fraction contains 5'-nucleotidase activity at approximately the same concentration as that in previous preparations of plasma membranes. In the presence of 0.01 M Mg++, 5'-nucleotidase exhibits a double pH optimum at pH values of 7.5 and 9.5. The activities of glucose-6-phosphatase and alkaline phosphatase are present in low amounts. Cytochrome P-450 is not detectable. Na+-K+-activation of ATPase is observed to the extent of 20–36% in about half of the assays. The availability of a method for preparation of intact bile canaliculi should prove useful for studying the biochemical events associated with the transport of bile constituents into canaliculi.
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Citations
Cites
The Carbon Monoxide-binding Pigment of Liver Microsomes
Omura, T., & Sato, R. (1964) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)82244-3 · Cited by 11,781
Cited by
Bile salt transporters: molecular characterization, function, and regulation
Trauner, M., & Boyer, J. L. (2003) · Physiological Reviews · doi:10.1152/physrev.00027.2002 · Cited by 999
A modified method for the isolation of the plasma membrane from rat liver
Ray, T. K. (1970) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(70)90159-8 · Cited by 572
Kinetic parameters of the interactions of retinol with lipid bilayers
Noy, N., & Xu, Z. J. (1990) · Biochemistry · doi:10.1021/bi00468a013 · Cited by 59
Thermodynamic parameters of the binding of retinol to binding proteins and to membranes
Noy, N., & Xu, Z. J. (1990) · Biochemistry · doi:10.1021/bi00468a014 · Cited by 41
Metadata
- Authors
- Song, C. S., Rubin, W., Rifkind, A. B., & Kappas, A.
- Venue
- The Journal of Cell Biology
- Publisher
- Rockefeller University Press
- Published
- 1969-04-01
- Volume
- 41
- Issue
- 1
- Pages
- 124-132
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2010315663
- Cited by
- 208
- References
- 1
- FWCI
- 14.88
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Song, C. S., Rubin, W., Rifkind, A. B., & Kappas, A. (1969). PLASMA MEMBRANES OF THE RAT LIVER. The Journal of Cell Biology. https://doi.org/10.1083/jcb.41.1.124
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
