The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
SERUM AND URINARY LYSOZYME (MURAMIDASE) IN MONOCYTIC AND MONOMYELOCYTIC LEUKEMIA
Open accessAbstract
Markedly increased quantities of lysozyme have been found in the serum and urine (ranging to 2.6 g per day) of ten consecutive cases of monocytic and monomyelocytic leukemia. The enzyme has been isolated from the urine of several cases and physicochemically and immunochemically characterized. It is apparently identical to the lysozyme of normal tears, saliva, leukocytes, and serum, but structurally different from the lysozyme of hen's egg white. The activity of the human enzyme assayed with M. lysodeikticus organisms is 3 to 12 times greater than egg white lysozyme at equivalent concentrations. An agar plate method has been developed for quantitating lysozyme activity in small samples (approximately 25 µl) of serum, urine, or other biological fluids. The range and reproducibility of this method were found to be superior to previously available lysozyme assay procedures. Present evidence indicates that lysozyme is the principal, if not the sole, product of the proliferating monocytes in monocytic and monomyelocytic leukemia, and quantitation of serum and urine lysozyme should be a useful diagnostic procedure for these leukemias.
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Citations
Cites
Isolation of lysozyme from egg white
Alderton, G., Ward, W. H., & Fevold, H. L. (1945) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)41625-5 · Cited by 279
Cited by
Lysozyme: an important defence molecule of fish innate immune system
Saurabh, S., & Sahoo, P. K. (2008) · Aquaculture Research · doi:10.1111/j.1365-2109.2007.01883.x · Cited by 1,648
Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3.
Abe, E., Miyaura, C., Sakagami, H., Takeda, M., Konno, K., Yamazaki, T., Yoshiki, S., & Suda, T. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.8.4990 · Cited by 1,020
Killing of gram-negative bacteria by lactoferrin and lysozyme.
Ellison, R. T., & Giehl, T. J. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115407 · Cited by 746
Cole, A. M., Shi, J., Ceccarelli, A., Kim, Y.-H., Park, A., & Ganz, T. (2001) · Blood · doi:10.1182/blood.v97.1.297 · Cited by 146
Regulation of immunity and inflammation by mediators from macrophages.
(1976) · PubMed Central · Cited by 92
Metadata
- Authors
- Osserman, E. F., & Lawlor, D. P.
- Venue
- The Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 1966-11-01
- Volume
- 124
- Issue
- 5
- Pages
- 921-952
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W1977802642
- Cited by
- 1,211
- References
- 1
- FWCI
- 28.30
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: SERUM AND URINARY LYSOZYME (MURAMIDASE) IN MONOCYTIC AND MONOMYELOCYTIC LEUKEMIA. https://app.cochat.ai/papers/10.1084/jem.124.5.921
- The paper
- Osserman, E. F., & Lawlor, D. P. (1966). SERUM AND URINARY LYSOZYME (MURAMIDASE) IN MONOCYTIC AND MONOMYELOCYTIC LEUKEMIA. The Journal of Experimental Medicine. https://doi.org/10.1084/jem.124.5.921
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
