The DOI matches its Crossref record.
ALTERATIONS OF MACROPHAGE FUNCTIONS BY MEDIATORS FROM LYMPHOCYTES
Open accessAbstract
Sensitized lymphocytes were incubated in vitro with the specific antigen Supernatants from these cultures were chromatographed on Sephadex G-100 columns. Supernatant fractions containing MIF, chemotactic factor, and lymphotoxin, but free of antigen and antibody, were incubated with normal peritoneal exudate macrophages. Macrophage adherence, phagocytosis, spreading, motility, and direct hexose monophosphate oxidation were enhanced, while protein synthesis was unaffected. Thus, antigen-stimulated lymphocytes secrete a factor or factors which enhance certain macrophage functions. Implications for models of cellular immunity and cellular hypersensitivity are discussed.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Nathan, C. F., Murray, H. W., Wiebe, M. E., & Rubin, B. Y. (1983) · The Journal of experimental medicine · doi:10.1084/jem.158.3.670 · Cited by 1,962
Self-citationCytokine-mediated inflammation in acute lung injury
Goodman, R. B., Pugin, J., Lee, J. S., & Matthay, M. A. (2003) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(03)00059-5 · Cited by 688
Induction of Macrophage Tumoricidal Activity by Granulocyte-Macrophage Colony-Stimulating Factor
Grabstein, K. H., Urdal, D. L., Tushinski, R. J., Mochizuki, D. Y., Price, V. L., Cantrell, M. A., Gillis, S., & Conlon, P. J. (1986) · Science · doi:10.1126/science.3083507 · Cited by 412
Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor
Ashcroft, G. S., Mills, S. J., Lei, K., Gibbons, L., Jeong, M.-J., Taniguchi, M., Burow, M., Horan, M. A., Wahl, S. M., & Nakayama, T. (2003) · Journal of Clinical Investigation · doi:10.1172/jci16288 · Cited by 335
Potential Role of Estrogens in Wound Healing
Ashcroft, G. S., & Ashworth, J. J. (2003) · American Journal of Clinical Dermatology · doi:10.2165/00128071-200304110-00002 · Cited by 130
Metadata
- Authors
- Nathan, C. F., Karnovsky, M. L., & David, J. R.
- Venue
- The Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 1971-06-01
- Volume
- 133
- Issue
- 6
- Pages
- 1356-1376
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W2101019091
- Cited by
- 492
- References
- 0
- FWCI
- 13.53
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: ALTERATIONS OF MACROPHAGE FUNCTIONS BY MEDIATORS FROM LYMPHOCYTES. https://app.cochat.ai/papers/10.1084/jem.133.6.1356
- The paper
- Nathan, C. F., Karnovsky, M. L., & David, J. R. (1971). ALTERATIONS OF MACROPHAGE FUNCTIONS BY MEDIATORS FROM LYMPHOCYTES. The Journal of Experimental Medicine. https://doi.org/10.1084/jem.133.6.1356
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
