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PEYER'S PATCHES: AN ENRICHED SOURCE OF PRECURSORS FOR I G A-PRODUCING IMMUNOCYTES IN THE RABBIT
Open accessAbstract
The proliferative and differentiative potential of Peyer's patch, peripheral blood, and popliteal lymph node cells was assessed by allogeneic cell transfer followed by quantitation of donor immunocytes by immunofluorescence. It was found that Peyer's patches are a highly enriched source of cells which have the potential to proliferate and differentiate into IgA-producing immunocytes and that the Peyer's patch cells are far more efficient in seeding the gut of irradiated recipient rabbits with donor cells that give rise to immunoglobulin-producing cells than cells from peripheral blood or popliteal lymph nodes.
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Citations
Cited by
New concepts in the generation and functions of IgA
Pabst, O. (2012) · Nature reviews. Immunology · doi:10.1038/nri3322 · Cited by 656
Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response
Hase, K., Kawano, K., Nochi, T., Pontes, G. S., Fukuda, S., Ebisawa, M., Kadokura, K., Tobe, T., Fujimura, Y., Kawano, S., et al. (2009) · Nature · doi:10.1038/nature08529 · Cited by 632
The role of interleukin-6 in mucosal IgA antibody responses in vivo
Ramsay, A. J., Husband, A. J., Ramshaw, L. A., Bao, S., Matthaei, K. I., Koehler, G., & Kopf, M. (1994) · Science · doi:10.1126/science.8160012 · Cited by 454
Regulation of the Germinal Center Response
Stebegg, M., Kumar, S. D., Silva-Cayetano, A., Fonseca, V. R., Linterman, M. A., & Graca, L. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02469 · Cited by 349
The Effects of Secretory IgA in the Mucosal Immune System
Li, Y., Jin, L., & Chen, T. (2020) · BioMed Research International · doi:10.1155/2020/2032057 · Cited by 336
Metadata
- Authors
- Craig, S. W., & Cebra, J. J.
- Venue
- The Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 1971-07-01
- Volume
- 134
- Issue
- 1
- Pages
- 188-200
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W2151231994
- Cited by
- 755
- References
- 0
- FWCI
- 4.75
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: PEYER'S PATCHES: AN ENRICHED SOURCE OF PRECURSORS FOR I G A-PRODUCING IMMUNOCYTES IN THE RABBIT. https://app.cochat.ai/papers/10.1084/jem.134.1.188
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- Craig, S. W., & Cebra, J. J. (1971). PEYER'S PATCHES: AN ENRICHED SOURCE OF PRECURSORS FOR I G A-PRODUCING IMMUNOCYTES IN THE RABBIT. The Journal of Experimental Medicine. https://doi.org/10.1084/jem.134.1.188
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
