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Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukemia.

Open access
Caligaris-Cappio, F, Gobbi, M, Bofill, M, Janossy, G·1982·The Journal of experimental medicine

Abstract

An infrequent (2-3%) B lymphocyte subpopulation was found in the normal human tonsil and lymph nodes that shows the phenotypic characteristics of B-chronic lymphocytic leukemia (B-CLL) (rosette formation with mouse erythrocytes, weak expression of membrane Ig, staining for HLA-DR, and OKT1 or Leu-1 detecting a T cell-associated p65 antigen). Preliminary evidence suggests that at least a subpopulation of these cells is found, in small proportions, within the germinal centers. These cells were not observed in the human bone marrow. B-CLL may involve this peripheral B lymphocyte subset.

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Metadata

Authors
Caligaris-Cappio, F., Gobbi, M., Bofill, M., & Janossy, G.
Venue
The Journal of experimental medicine
Published
1982-02-01
Volume
155
Issue
2
Pages
623-628
ISSN
  • 0022-1007 (ISSN-L)
  • 1540-9538
OpenAlex
W2114146017
Cited by
469
References
0
FWCI
30.69
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukemia. https://app.cochat.ai/papers/10.1084/jem.155.2.623
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Caligaris-Cappio, F., Gobbi, M., Bofill, M., & Janossy, G. (1982). Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukemia. The Journal of experimental medicine. https://doi.org/10.1084/jem.155.2.623

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.