The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Detection of human papilloma virus in paraffin-embedded tissue using the polymerase chain reaction.
Open accessAbstract
Human papilloma virus (HPV) DNA sequences have been detected in paraffin-embedded tissue using an enzymatic in vitro amplification technique known as the polymerase chain reaction. Amplification of a HPV DNA sequence before its detection with a cDNA probe significantly increases the rapidity as well as the sensitivity of detection such that a single 5-10-micron thick paraffin-embedded tissue section can be analyzed within 24 h. The assay specifically detected HPV 16 or 18 without crossreactivity with HPV 6 or 11. As few as 20 viral copies could be detected. The rapid and sensitive analysis of HPV in normal and pathological tissues using this technique may contribute significantly to identifying the role of HPV as a risk factor in carcinoma.
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Cites
Saiki, R. K., Scharf, S., Faloona, F., Mullis, K. B., Horn, G. T., Erlich, H. A., & Arnheim, N. (1985) · Science · doi:10.1126/science.2999980 · Cited by 8,956
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Cited by
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Almoguera, C., Shibata, D., Forrester, K., Martin, J., Arnheim, N., & Perucho, M. (1988) · Cell · doi:10.1016/0092-8674(88)90571-5 · Cited by 2,114
Self-citationThe Agent of Bacillary Angiomatosis: An Approach to the Identification of Uncultured Pathogens
Relman, D. A., Loutit, J. S., Schmidt, T. M., Falkow, S., & Tompkins, L. S. (1990) · New England Journal of Medicine · doi:10.1056/nejm199012063232301 · Cited by 901
Demmler, G. J., Buffone, G. J., Schimbor, C. M., & May, R. A. (1988) · Journal of Infectious Diseases · doi:10.1093/infdis/158.6.1177 · Cited by 481
Kievits, T., van Gemen, B., van Strijp, D., Schukkink, R., Dircks, M., Adriaanse, H., Malek, L., Sooknanan, R., & Lens, P. (1991) · Journal of Virological Methods · doi:10.1016/0166-0934(91)90069-c · Cited by 408
Guillaume J.J.M., V. E., Schoone, G. J., Kroon, N. C. M., & Ebeling, S. B. (1992) · Molecular and Biochemical Parasitology · doi:10.1016/0166-6851(92)90208-2 · Cited by 377
Metadata
- Authors
- Shibata, D. K., Arnheim, N., & Martin, W. J.
- Venue
- The Journal of experimental medicine
- Publisher
- Rockefeller University Press
- Published
- 1988-01-01
- Volume
- 167
- Issue
- 1
- Pages
- 225-230
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W1986432875
- Cited by
- 707
- References
- 1
- FWCI
- 98.08
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Shibata, D. K., Arnheim, N., & Martin, W. J. (1988). Detection of human papilloma virus in paraffin-embedded tissue using the polymerase chain reaction. The Journal of experimental medicine. https://doi.org/10.1084/jem.167.1.225
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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