The DOI matches its Crossref record.
Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer.
Open accessAbstract
Typing of DNA from 94 unrelated children with celiac disease (CD) with HLA-DQA1 and -DQB1 allele-specific oligonucleotide probes revealed that all but one (i.e., 98.9%) may share a particular combination of a DQA1 and a DQB1 gene. These genes are arranged in cis position on the DR3DQw2 haplotype and in trans position in DR5DQw7/DR7DQw2 heterozygous individuals. Thus, most CD patients may share the same cis- or trans-encoded HLA-DQ alpha/beta heterodimer.
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Cited by
Husby, S., Koletzko, S., Korponay‐Szabó, I. R., Mearin, M. L., Phillips, A., Shamir, R., Troncone, R., Giersiepen, K., Branski, D., Catassi, C., et al. (2012) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e31821a23d0 · Cited by 2,683
(2) Classification and diagnosis of diabetes
American Diabetes Association (2015) · Diabetes Care · doi:10.2337/dc15-s005 · Cited by 1,841
Coeliac disease: dissecting a complex inflammatory disorder
Sollid, L. M. (2002) · Nature Reviews Immunology · doi:10.1038/nri885 · Cited by 964
Self-citationDi Sabatino, A., & Corazza, G. R. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60254-3 · Cited by 555
HLA class II‐associated genetic susceptibility in multiple sclerosis: A critical evaluation
Olerup, O., & Hillert, J. (1991) · Tissue Antigens · doi:10.1111/j.1399-0039.1991.tb02029.x · Cited by 490
Metadata
- Authors
- Sollid, L. M., Markussen, G., Ek, J., Gjerde, H., Vartdal, F., & Thorsby, E.
- Venue
- The Journal of experimental medicine
- Publisher
- Rockefeller University Press
- Published
- 1989-01-01
- Volume
- 169
- Issue
- 1
- Pages
- 345-350
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W2048796508
- Cited by
- 931
- References
- 0
- FWCI
- 41.23
- Type
- journal article
- Language
- en
- Open access
- green
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- Sollid, L. M., Markussen, G., Ek, J., Gjerde, H., Vartdal, F., & Thorsby, E. (1989). Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer. The Journal of experimental medicine. https://doi.org/10.1084/jem.169.1.345
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