The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins.
Open accessAbstract
A cDNA encoding a new human lymphocyte cell surface molecule has been isolated and shown to identify a fourth member of a recently discovered family of adhesion proteins. This lymphocyte-associated molecule (LAM-1) is uniquely composed of multiple distinct domains, one domain homologous with animal lectins, one homologous with epidermal growth factor, and two short consensus repeat units similar to those found in C3/C4 binding proteins. This cDNA clone hybridized with RNAs found in B cell lines and T lymphocytes, but not with RNA from other cell types. The amino acid sequence of LAM-1 is 77% homologous with the sequence of the mouse lymphocyte homing receptor, suggesting that LAM-1 may function in human lymphocyte adhesion. The LAM-1 gene is located on chromosome 1q23-25, as is another member of this adhesion family, suggesting that this new family of proteins may be encoded by a cluster of "adhesion protein" loci.
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Metadata
- Authors
- Tedder, T. F., Isaacs, C. M., Ernst, T. J., Demetri, G. D., Adler, D. A., & Disteche, C. M.
- Venue
- The Journal of experimental medicine
- Publisher
- Rockefeller University Press
- Published
- 1989-07-01
- Volume
- 170
- Issue
- 1
- Pages
- 123-133
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W2121976226
- Cited by
- 299
- References
- 21
- FWCI
- 11.44
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins. https://app.cochat.ai/papers/10.1084/jem.170.1.123
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- Tedder, T. F., Isaacs, C. M., Ernst, T. J., Demetri, G. D., Adler, D. A., & Disteche, C. M. (1989). Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins. The Journal of experimental medicine. https://doi.org/10.1084/jem.170.1.123
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
