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Cited by 6,477Cell Adhesion Molecules ResearchT-cell and B-cell ImmunologyBiochemical and Structural Characterization

Adhesion receptors of the immune system

Springer, Timothy A.·1990·Nature
DOI 10.1038/346425a0
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Abstract

The adhesive interactions of cells with other cells and with the extracellular matrix are crucial to all developmental processes, but have a central role in the functions of the immune system throughout life. Three families of cell-surface molecules regulate the migration of lymphocytes and the interactions of activated cells during immune responses.

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Crossref · 10.1038/346425a0

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Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • In the presence of infectious organisms (foreign antigens), the immune cells aggregate at the site of the infection and through their adhesion receptors they adhere to cells bearing a foreign antigen.

    “In the presence of infectious organisms (foreign antigens), the immune cells aggregate at the site of the infection and through their adhesion receptors they adhere to cells bearing a foreign antigen (Springer, 1990).”

    From Identification of Candidate Signature Genes and Key Regulators Associated With Trypanotolerance in the Sheko Breed (2019) · cites this paper as Springer, 1990

  • Among the 30 enriched terms, two GO-terms are T-cell chemotaxis and cell-cell adhesion which play a critical role in the immune system.

    “Interestingly, among the 30 enriched terms, two GO-terms are T-cell chemotaxis and cell–cell adhesion which play a critical role in the immune system (Springer, 1990; Gerard and Rollins, 2001; Bach et al., 2007).”

    From Identification of Candidate Signature Genes and Key Regulators Associated With Trypanotolerance in the Sheko Breed (2019) · cites this paper as Springer, 1990

  • The movement or circulation of immune cells in the blood and lymph as non-adherent cells and in tissues as adherent cells is critical for patrolling the body against infectious organisms effectively.

    “The movement or circulation of immune cells in the blood and lymph as non-adherent cells and in tissues as adherent cells is critical for patrolling the body against infectious organisms effectively (Springer, 1990).”

    From Identification of Candidate Signature Genes and Key Regulators Associated With Trypanotolerance in the Sheko Breed (2019) · cites this paper as Springer, 1990

Cited by

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Authors
Springer, T. A.
Affiliations
Harvard University (US)
Corresponding author
Springer, Timothy A.
ORCID
Springer, Timothy A.
Venue
Nature
Publisher
Springer Science and Business Media LLC
Published
1990-08
Volume
346
Issue
6283
Pages
425-434
ISSN
  • 0028-0836 (ISSN-L)
  • 1476-4687
DOI
10.1038/346425a0
OpenAlex
W1966286149
Cited by
6,477
References
0
Citations by year
2026: 19 · 2025: 27 · 2024: 36 · 2023: 34 · 2022: 47 · 2021: 44 · 2020: 47 · 2019: 62 · 2018: 47 · 2017: 53 · 2016: 64 · 2015: 57 · 2014: 71 · 2013: 71 · 2012: 65
FWCI
23.41
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
  • Nature (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Immunology and Allergy › Cell Adhesion Molecules Research
  • Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biochemical and Structural Characterization
Keywords
cell adhesion receptors, cell adhesion, lymphocyte migration, immune response, extracellular matrix, cell surface molecules, immune cell activation, cell-cell interactions
MeSH terms
Animals, Antigens, Differentiation, T-Lymphocyte, Cell Adhesion, Immunity, Lymphocytes, Receptors, Immunologic, Receptors, Virus, Cell Adhesion Molecules, Integrins, Receptors, Leukocyte-Adhesion, CD2 Antigens

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