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Chemoattraction of human blood T lymphocytes by interleukin-15.
Open accessAbstract
Recombinant interleukin (IL)-15, derived from a simian kidney epithelial cell line, is a chemoattractant for human blood T lymphocytes judged by its ability to increase the proportion of cells in polarized morphology, to stimulate invasion of collagen gels containing IL-15, and to increase the proportion of locomotor cells observed by time-lapse videorecording. The ability of lymphocytes to respond was partly, but not completely, inhibited by pretreatment with anti-IL-2 receptor beta-chain. The activity of IL-15 was completely abolished by preincubation with aIL-15 but unaffected by preincubation with aIL-2. No response of monocytes, neutrophils, or B lymphocytes to IL-15 was observed.
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Cited by
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Waldmann, T. A., & Tagaya, Y. (1999) · Annual Review of Immunology · doi:10.1146/annurev.immunol.17.1.19 · Cited by 721
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Barnes, P. J., Chung, K. F., & Page, C. P. (1998) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01381-4 · Cited by 717
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Lucey, D. R., Clerici, M., & Shearer, G. M. (1996) · Clinical Microbiology Reviews · doi:10.1128/cmr.9.4.532 · Cited by 666
Chung, K. F., & Barnes, P. J. (1999) · Thorax · doi:10.1136/thx.54.9.825 · Cited by 638
Metadata
- Authors
- Wilkinson, P. C., & Liew, F. Y.
- Venue
- The Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 1995-03-01
- Volume
- 181
- Issue
- 3
- Pages
- 1255-1259
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W2094342978
- Cited by
- 290
- References
- 0
- FWCI
- 9.43
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Wilkinson, P. C., & Liew, F. Y. (1995). Chemoattraction of human blood T lymphocytes by interleukin-15. The Journal of Experimental Medicine. https://doi.org/10.1084/jem.181.3.1255
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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