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Polyguluronic acid alleviates doxorubicin-induced cardiotoxicity by suppressing Peli1-NLRP3 inflammasome-mediated pyroptosis

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Munronoid I Ameliorates DSS-Induced Mouse Colitis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Via Modulation of NLRP3

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An updated view on the functions of caspases in inflammation and immunity

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Fit to dwell in many places – The growing diversity of intracellular Salmonella niches

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Update of cellular responses to the efferocytosis of necroptosis and pyroptosis

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Versatility of gasdermin D beyond pyroptosis

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Targeting inflammasomes as an immunotherapeutic strategy for cancer

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The Interplay between Salmonella enterica Serovar Typhimurium and the Intestinal Mucosa during Oral Infection

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Intracellular niche switching as host subversion strategy of bacterial pathogens

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Human GBP1 facilitates the rupture of the Legionella- containing vacuole and inflammasome activation

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New insights into the noncanonical inflammasome point to caspase-4 as a druggable target

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New Insights Relating Gasdermin B to the Onset of Childhood Asthma

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Molecular Mechanisms of Pyroptosis

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I’m Infected, Eat Me! Innate Immunity Mediated by Live, Infected Cells Signaling To Be Phagocytosed

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Pyroptosis and its role in autoimmune skin disease

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Consequences of Epithelial Inflammasome Activation by Bacterial Pathogens

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Bucket lists must be completed during cell death

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Conciliatory Anti-Allergic Decoction Attenuates Pyroptosis in RSV-Infected Asthmatic Mice and Lipopolysaccharide (LPS)-Induced 16HBE Cells by Inhibiting TLR3/NLRP3/NF-κB/IRF3 Signaling Pathway

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Gasdermin D protects against Streptococcus equi subsp. zooepidemicus infection through macrophage pyroptosis

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To die or not to die: Gasdermins in intestinal health and disease

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NLRP3 inflammasome is attenuated in patients with Mycobacterium avium complex lung disease and correlated with decreased interleukin-1β response and host susceptibility

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HDAC inhibitor regulates the tumor immune microenvironment via pyroptosis in triple negative breast cancer

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Pyroptosis in Diabetic Peripheral Neuropathy and its Therapeutic Regulation

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Dynamic imaging reveals surface exposure of virulent Leishmania amastigotes during pyroptosis of infected macrophages

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Gasdermins in Innate Host Defense Against Entamoeba histolytica and Other Protozoan Parasites

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Pyroptosis executioner gasdermin D contributes to host defense and promotes Th 1 immune response during Neospora caninum infection

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Fundamental mechanisms of cell death for polycystic ovary syndrome

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Proteolytic control of regulated necrosis

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NLRP3 as a therapeutic target in cyclophosphamide-associated toxicities

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Pyroptosis in neurodegenerative diseases: What lies beneath the tip of the iceberg?

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GSDMD-mediated pyroptosis restrains intracellular Chlamydia trachomatis growth in macrophages

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The hypoxia-related signature predicts prognosis, pyroptosis and drug sensitivity of osteosarcoma

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Efferocytosis: a double-edged sword in microbial immunity

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Role of Pyroptosis in Endometrial Cancer and Its Therapeutic Regulation

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Resistance of hypervirulent Klebsiella pneumoniae to cathepsin B-mediated pyroptosis in murine macrophages

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Dying for a cause: The pathogenic manipulation of cell death and efferocytic pathways

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Magnolol attenuates macrophage pyroptosis triggered by Streptococcus equi subsp. zooepidemicus

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Enterovirus 71 induces pyroptosis of human neuroblastoma SH-SY5Y cells through miR-146a/ CXCR4 axis

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Yersinia pseudotuberculosisYopJ Limits Macrophage Response by Downregulating COX-2-Mediated Biosynthesis of PGE2 in a MAPK/ERK-Dependent Manner

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Pyroptotic Patterns in Blood Leukocytes Predict Disease Severity and Outcome in COVID-19 Patients

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Apoptotic signaling clears engineered Salmonella in an organ-specific manner

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Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophagesPreprint

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Identification of immune characteristic biomarkers and therapeutic targets in cuproptosis for sepsis by integrated bioinformatics analysis and single-cell RNA sequencing analysis

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MAP3K13-232aa encoded by circMAP3K13 enhances cisplatin-induced pyroptosis by directly binding to IKKα in gastric adenocarcinoma

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Activation and manipulation of inflammasomes and pyroptosis during bacterial infections

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Development and validation of a prognostic model related to pyroptosis-related genes for esophageal squamous cell carcinoma using bioinformatics analysis

Zhang, W., Zhang, P., Jiang, J., Peng, K., Shen, Z., & Kang, M. (2022) · Journal of Thoracic Disease · doi:10.21037/jtd-22-948 · Cited by 9

Bitongqing Attenuates CIA Rats by Suppressing Macrophage Pyroptosis and Modulating the NLRP3/Caspase-1/GSDMD Pathway

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A Plant-Derived Nucleic Acid Reconciles Type I IFN and a Pyroptotic-like Event in Immunity against Respiratory Viruses

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Types of cell death and their relations to host immunological pathways

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Progression of Kidney Fibrosis after Sepsis

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Gasdermin-D pores induce an inactivating caspase-4 cleavage that limits IL-18 production in the intestinal epithelium

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Gasdermins: multifunctional effectors of membrane permeabilization across cellular compartments

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Regulation of gasdermins in pyroptosis and cytokine release

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Polydatin alleviates mycoplasma pneumoniae-induced injury via inhibition of Caspase-1/GSDMD-dependent pyroptosis

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Deciphering the Role of Pyroptosis Impact on Cardiovascular Diseases

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Mild endoplasmic reticulum stress alleviates FB1-triggered intestinal pyroptosis via the Sec62-PERK pathway

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Developmental immunology and role of host defenses in fetal and neonatal susceptibility to infection

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Gallic Acid-Modified Polyethylenimine–Polypropylene Carbonate–Polyethylenimine Nanoparticles: Synthesis, Characterization, and Anti-Periodontitis Evaluation

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Disulfidptosis: A New Target for Parkinson’s Disease and Cancer

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GSDM family and glioma

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Funerals and Feasts: The Immunological Rites of Cell Death.

Galimberti, V., Rothlin, C. V., & Ghosh, S. (2019) · Europe PMC (PubMed Central) · Cited by 7

RIPK1 and RIPK3 in antibacterial defence

Yeap, H. W., & Chen, K. W. (2022) · Biochemical Society Transactions · doi:10.1042/bst20211242 · Cited by 8

Identification and verification of disulfidptosis-related genes in sepsis-induced acute lung injury

Zhang, A., Wang, X., Wen, L., Zhu, H., & Pan, J. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1430252 · Cited by 7

NLRP1-dependent activation of Gasdermin D in neutrophils controls cutaneous leishmaniasis

Goris, M., Passelli, K., Peyvandi, S., Díaz-Varela, M., Billion, O., Prat-Luri, B., Demarco, B., Desponds, C., Termote, M., Iniguez, E., et al. (2024) · PLoS Pathogens · doi:10.1371/journal.ppat.1012527 · Cited by 7

Cracking the Cell Death CodePreprint

Rothlin, C. V., & Ghosh, S. (2019) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a036343 · Cited by 8

Type-3 Secretion System–induced pyroptosis protects Pseudomonas against cell-autonomous immunityPreprint

Eren, E., Planès, R., Buyck, J. M., Bordignon, P.-J., Colom, A., Cunrath, O., Dreier, R. F., Santos, J. C., Duplan-Eche, V., Näser, E., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/650333 · Cited by 9

Proton-activated chloride channel governs phagosome-mediated antibacterial immunity in peritoneal macrophages

Cheng, Y., Chu, J., Limjunyawong, N., Chen, J., Ye, Y., Chen, K. H., Koylass, N., Sun, S., Dong, X., & Qiu, Z. (2025) · The Journal of Experimental Medicine · doi:10.1084/jem.20250312 · Cited by 6

Autophagy May Allow a Cell to Forbear Pyroptosis When Confronted With Cytosol-Invasive Bacteria

Harvest, C. K., & Miao, E. A. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.871190 · Cited by 6

Immunization with recombinant Salmonella expressing SspH2-EscI protects mice against wild type Salmonella infection

Hu, M., Zhao, W., Li, H., Gu, J., Yan, Q., Zhou, X., Pan, Z., Cui, G., & Jiao, X. (2018) · BMC Veterinary Research · doi:10.1186/s12917-018-1404-5 · Cited by 6

Dexmedetomidine Mitigates Acute Lung Injury by Enhancing M2 Macrophage Polarization and Inhibiting RAGE/Caspase-11-Mediated Pyroptosis

Zhao, Y., Li, K., Wang, L., Kuang, G., Xie, K., & Lin, S. (2024) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2912409 · Cited by 5

Identification of a disulfidptosis-related genes signature for diagnostic and immune infiltration characteristics in cervical cancer

Zhou, Q. Y., Song, B., He, Y., Zhang, Z., Chen, S., Chen, W., Li, X., & Jiang, J. (2025) · PLoS ONE · doi:10.1371/journal.pone.0322387 · Cited by 5

Nasal microbionts differentially colonize and elicit cytokines in human nasal epithelial organoids

Boyd, A. I., Kafer, L. A., Escapa, I. F., Kambal, A., Tariq, H., Hilsenbeck, S. G., Nguyen‐Phuc, H., Rajan, A., Lensmire, J. M., Patras, K. A., et al. (2025) · mSphere · doi:10.1128/msphere.00493-25 · Cited by 6

Necroptosis in apical periodontitis: A programmed cell death with multiple roles

Liu, H., Fan, W., & Fan, B. (2023) · Journal of Cellular Physiology · doi:10.1002/jcp.31073 · Cited by 5

Effects and mechanisms of Salmonella plasmid virulence gene spv on host-regulated cell death

Li, K., You, J., Li, Y., Huang, R., & Wu, S. (2024) · Current Microbiology · doi:10.1007/s00284-024-03612-0 · Cited by 6

Innate immune responses and monocyte-derived phagocyte recruitment in protective immunity to pathogenic bacteria: insights from Legionella pneumophila

Mascarenhas, D. P. A., & Zamboni, D. S. (2024) · Current Opinion in Microbiology · doi:10.1016/j.mib.2024.102495 · Cited by 5

Warfare and defense: The host response to Cryptococcus infection

Dutra, F. F., Albuquerque, P. C., Rodrigues, M. L., & Fonseca, F. L. (2017) · Fungal Biology Reviews · doi:10.1016/j.fbr.2017.09.002 · Cited by 6

A sandPIT for Salmonella to play with efferosomes

Morrison, R., Luk, C. H., & Gutierrez, M. G. (2022) · Cell Host & Microbe · doi:10.1016/j.chom.2022.01.008 · Cited by 5

IL‐1β, IL‐18, and eicosanoids promote neutrophil recruitment to pore‐induced intracellular traps following pyroptosis

Jørgensen, I., Lopez, J. P., Laufer, S., & Miao, E. A. (2016) · European Journal of Immunology · doi:10.1002/eji.201646647 · Cited by 148

Neutrophil Inflammasomes Sense the Subcellular Delivery Mechanism of Translocated Bacterial Effectors and Toxins

Oh, C., Li, L., Verma, A., Reuven, A. D., Miao, E. A., Bliska, J. B., & Aachoui, Y. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111688 · Cited by 32

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria (111.33)

Miao, E. A., Leaf, I. A., Treuting, P. R., Mao, D. P., Sarkar, A., Wewers, M. D., & Aderem, A. A. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.186.supp.111.33 · Cited by 35

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

Miao, E. A., Leaf, I. A., Treuting, P. M., Mao, D. P., Dors, M., Sarkar, A., Warren, S. E., Wewers, M. D., & Aderem, A. (2010) · Nature Immunology · doi:10.1038/ni.1960 · Cited by 1,336

Neutrophil Inflammasomes Sense the Subcellular Delivery Mechanism of Translocated Bacterial Effectors and ToxinsPreprint

Oh, C., Li, L., Verma, A., Reuven, A. D., Miao, E. A., Bliska, J. B., & Aachoui, Y. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4019721