Unique pathological tau conformers from Alzheimer’s brains transmit tau pathology in nontransgenic mice
Guo, Jing L., Narasimhan, Sneha, Changolkar, Lakshmi, He, Zhuohao, Stieber, Anna, Zhang, Bin, Gathagan, Ronald J., Iba, Michiyo, McBride, Jennifer D., Trojanowski, John Q., Lee, Virginia M.Y.·2016·Journal of Experimental Medicine
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Items 401–441 of 441
- Additional file 2 of Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s diseaseGarrett S. Gibbons, Kim, Soo-Jung, Wu, Qihui, Dawn M. Riddle, Susan N. Leight, Lakshmi N. Changolkar, Xu, Hong, Emily S. Meymand, Mia O’Reilly, Bin Zhang et al. · 2020 · Figshare
- Additional file 2 of SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer’s diseaseMaria Bichmann, Prat Oriol, Nuria, Ebru Ercan-Herbst, David C. Schöndorf, Gomez Ramos, Borja, Vera Schwärzler, Marie Astrid Neu, Annabelle Schlüter, Wang, Xue, Liang Jin et al. · 2021 · Figshare
- Additional file 1 of Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic TauopathySi Jie Tang, Arman Fesharaki‐Zadeh, Hideyuki Takahashi, Sarah Helena Nies, Levi M. Smith, Anin Luo, Annabel S. Chyung, Marius Chiasseu, Stephen M. Strittmatter · 2020 · Figshare
- Additional file 1 of TDP-43 pathology is associated with increased tau burdens and seedingSandra O. Tomé, Grigoria Tsaka, Alicja Ronisz, Simona Ospitalieri, Klara Gawor, Luis Aragão Gomes, Markus Otto, Christine A. F. Von Arnim, Philip Van Damme, Ludo Van Den Bosch et al. · 2024 · Figshare
- Additional file 3 of SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer’s diseaseMaria Bichmann, Prat Oriol, Nuria, Ebru Ercan-Herbst, David C. Schöndorf, Gomez Ramos, Borja, Vera Schwärzler, Marie Astrid Neu, Annabelle Schlüter, Wang, Xue, Jin, Liang et al. · 2021 · Figshare
- Additional file 6 of P62 accumulates through neuroanatomical circuits in response to tauopathy propagationFrançois-Xavier Blaudin de Thé, Benjamin Lassus, Ari W. Schaler, Stephanie L. Fowler, Chris N. Goulbourne, Ross Jeggo, Mannoury la Cour, Clotilde, Mark John Millan, Karen Duff · 2021 · Figshare
- Additional file 1 of Mouse serum albumin induces neuronal apoptosis and tauopathiesHou, Sheng-jie, Huang, Ya-ru, Jie Zhu, Jia, Ying-bo, Niu, Xiao-yun, Yang, Jin-ju, Yu, Xiao-lin, Du, Xiao-yu, Liang, Shi-yu, Cui, Fang et al. · 2024 · Figshare
- Additional file 2 of Human tauopathy strains defined by phosphorylation in R1-R2 repeat domains of tauEthan D. Smith, Quan Vo, Benoit I. Giasson, Borchelt, David R., Stefan Prokop, Paramita Chakrabarty · 2024 · Figshare
- Additional file 2 of Mouse serum albumin induces neuronal apoptosis and tauopathiesHou, Sheng-jie, Huang, Ya-ru, Jie Zhu, Jia, Ying-bo, Niu, Xiao-yun, Yang, Jin-ju, Yu, Xiao-lin, Du, Xiao-yu, Liang, Shi-yu, Cui, Fang et al. · 2024 · Figshare
- Additional file 1 of Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD miceArgyro Thalia Delizannis, Annelies Nonneman, Wangchen Tsering, An De Bondt, Ilse Van den Wyngaert, Bin Zhang, Emily S. Meymand, Modupe F. Olufemi, Pyry P. Koivula, Shaniya Maimaiti et al. · 2021 · Figshare
- Additional file 1 of Comparison of size distribution and (Pro249-Ser258) epitope exposure in in vitro and in vivo derived Tau fibrilsAndré Filipe Domingos Marreiro, Kristof Van Kolen, Sousa, Cristiano, Liesbet Temmerman, Bruno Vasconcelos, Rosa Crespo Rodriguez, van Weering, Jan R. T., Debby Van Dam, De Deyn, Peter P., Adrian C. Apetri et al. · 2020 · Figshare
- Additional file 1 of LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progressionNoah Lubben, Julia K. Brynildsen, Connor M. Webb, Li, Howard L., Cheryl E. G. Leyns, Lakshmi N. Changolkar, Bin Zhang, Emily S. Meymand, Mia O’Reilly, Madaj, Zach et al. · 2024 · Figshare
- Additional file 1 of Human tauopathy strains defined by phosphorylation in R1-R2 repeat domains of tauEthan D. Smith, Quan Vo, Benoit I. Giasson, Borchelt, David R., Stefan Prokop, Paramita Chakrabarty · 2023 · Figshare
- Additional file 4 of Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s diseaseGarrett S. Gibbons, Kim, Soo-Jung, Wu, Qihui, Dawn M. Riddle, Susan N. Leight, Lakshmi N. Changolkar, Xu, Hong, Emily S. Meymand, Mia O’Reilly, Bin Zhang et al. · 2020 · Figshare
- Additional file 1 of SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer’s diseaseMaria Bichmann, Prat Oriol, Nuria, Ebru Ercan-Herbst, David C. Schöndorf, Gomez Ramos, Borja, Vera Schwärzler, Marie Astrid Neu, Annabelle Schlüter, Wang, Xue, Jin, Liang et al. · 2021 · Figshare
- Additional file 1 of Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s diseaseGarrett S. Gibbons, Kim, Soo-Jung, Wu, Qihui, Dawn M. Riddle, Susan N. Leight, Lakshmi N. Changolkar, Xu, Hong, Emily S. Meymand, Mia O’Reilly, Bin Zhang et al. · 2020 · Figshare
- Additional file 3 of Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s diseaseGarrett S. Gibbons, Kim, Soo-Jung, Wu, Qihui, Dawn M. Riddle, Susan N. Leight, Lakshmi N. Changolkar, Xu, Hong, Emily S. Meymand, Mia O’Reilly, Bin Zhang et al. · 2020 · Figshare
- Additional file 3 of Mouse serum albumin induces neuronal apoptosis and tauopathiesHou, Sheng-jie, Huang, Ya-ru, Zhu, Jie, Jia, Ying-bo, Niu, Xiao-yun, Yang, Jin-ju, Yu, Xiao-lin, Du, Xiao-yu, Liang, Shi-yu, Cui, Fang et al. · 2024 · Figshare
- Cerebellar volumes’ selective association with MoCA over MMSE: a diagnostic insight into mild cognitive impairment and mild dementiaMaria Devita, Chiara Ceolin, Chiara Begliomini, Michela Sarlo, Alessandra Coin, A. Bertoldo, Giuseppe Sergi, Daniela Mapelli, Marina DE RUI · 2026 · Neurological Sciences
- PICALM Genetic Variant Alters mRNA Expression Without Affecting Protein Levels or Tau Spreading in Alzheimer’s DiseaseKunié Ando, Lidia Lopez‐Gutierrez, Salwa Mansour, Zehra Yilmaz, Luce Dauphinot, Jan Verheijen, Gaëlle Fontaine, Carolina Quintanilla‐Sánchez, Emmanuel Aydin, Emilie Doeraene et al. · 2026 · Cells
- Les nanotubes comme nouvelle voie de transfert et de propagation de la protéine Tau pathologiqueMeryem Tardivel · 2017 · theses.fr (ABES)
- Development of Inhibitors of Amyloid Fibril PropagationMaya Bendifallah · 2019 · theses.fr (ABES)
- Study of the Neuron-Astrocyte Relationship in a Rodent Model of TauopathyAnastasie Maté de Gérando · 2019 · theses.fr (ABES)
- Déterminants structuraux d’agrégats de Tau distincts : vers de nouveaux outils moléculaires pour discriminer les tauopathiesEmilie Caroux · 2019 · theses.fr (ABES)
- Prévention du phénomène de nucléation et de la propagation des tauopathies par immunothérapie passive utilisant un anticorps ciblant une région centrale de la protéine tauMarie Albert · 2018 · theses.fr (ABES)
- Propagation axonale des pathologies Tau et Aβ dans la maladie d'Alzheimer : à la recherche de propagons dans le circuit subiculo-fornico-mamillaireManon Thierry · 2020 · theses.fr (ABES)
- Étude du rôle de la microglie dans la propagation de la protéine Tau : mise en place de nouveaux modèlesCharlotte Duwat · 2021 · theses.fr (ABES)
- Transmission of Alzheimer pathology in murine and primate models : from proteinopathies to neuronal and cognitive impairmentsSuzanne Lam · 2021 · theses.fr (ABES)
- The Use of Localized Proteomics to Understand the Pathogenesis of Alzheimer's DiseaseGeoffrey Pires · 2021 · theses.fr (ABES)
- Structures and Dynamics of Tau Assemblies from Solid-State NMRNadia El Mammeri, Mei Hong · 2026 · Accounts of Chemical Research
- SynCAR platform for capturing neuronal synaptic proteopathic seedsRebecca M. Sebastian, Robert Kupp, Dhaval M. Nanavati, Iwan Parfentev, Thomas J. Krzystek, Nandini Romanul, Kiran Yanamandra, Christina N Preiss, Justine D. Manos, Hai-yan Wu et al. · 2026 · iScience
- Lysine methylation is an endogenous post-translational modifications of tau protein in human brain and a modulator of aggregation propensityMarisel Sanchez, Jeff Kuret · 2026 · Methods in enzymology on CD-ROM/Methods in enzymology
- Amyloid beta exacerbates Tau-seeded pathology and drives tangle formation in human neuronal xenograftsBart De Strooper, Jacqueline F. M. van Vierbergen, Sriram Balusu, Katrien Horré, Nóra Baligács, Dries T'svyen, Iordana Chrysidou, Annerieke S. R. Sierksma, Lutgarde Serneels, Dietmar Rudolf Thal et al. · 2026 · Research Square
- Evolution of the Neurometabolic Cascade of Traumatic Brain InjuryWilliam P. Flavin, Kevin C. Bickart, Janel E. Le Belle, Talin Babikian, Madison Harris, Joshua Kamins, Jose A. Pineda, Meeryo C. Choe, Christopher C. Giza, Mayumi L. Prins · 2026 · Neurologic Clinics
- New Insights into Neurodegenerative Diseases: Intercellular TransmissionJia Xiu-lan, Tong-Hua Zhao, Weihong Guo, Jing Xue, Da‐Chuan Yin · 2026 · ACS Chemical Neuroscience
- Cofactor-Free Tau Filaments Are Dynamic and Undergo Structural Evolution Driven by Thermodynamic ControlWyatt C. Powell, N. Yan, Eric Tse, Arthur A Melo, Jennifer A. Vasquez, Daniel R. Southworth, Jason E. Gestwicki · 2026 · Journal of the American Chemical Society
- A third-generation, high-affinity biparatopic anti-tau antibody inhibits intracellular tau aggregation seeded by Alzheimer’s brain extractsEric Hatterer, Lucile Broyer, Sara Pecoraro, Fabien Cusin, Naz Simsek, John J. P. Brevé, Mathieu Clavel, Kevin Llewelyn Batenburg, Bart Klein, Thuur Zuidweg et al. · 2026 · Alzheimer s Research & Therapy
- When Pathologies Collide: The Intersection of Tau and Alpha-Synuclein in Neurodegenerative DiseasesJenna N. Hunt, Sandhya Kortagere · 2026 · Molecular Neurobiology
- Conformation-specific anti-pathological tau antibody raised against AD brain-derived seed-competent tau reduces tau pathology in transgenic miceKiran Yanamandra, Nandini Romanul, Hiral Patel, Hollie Sanders, Rui Chang, Anhdao Darcy, Nathan Brown, Christyne Ayne Kane, Hai-Yan Wu, Kalpana Jagtap et al. · 2026 · Molecular Neurodegeneration Advances
- Harmful tau spreads like self-propagating prion proteinsKayleigh Mason-Chalmers, José A. Rodríguez · 2026 · Nature
- Templated paired helical filament formation and tau fold-dependent inclusion morphologies in primary neuronsMelissa Huang, Sofia Lövestam, Kimberly Ai Xian Cheam, Bernardino Francesco Ghetti, William A. McEwan, Sjors H. W. Scheres, Michel Goedert · 2026 · bioRxiv (Cold Spring Harbor Laboratory)