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THE EXISTENCE OF TWO FORMS OF HYPERTENSIN
Open accessAbstract
Two types of hypertensin have been demonstrated by means of counter-current distribution. The first type is the product of the action of the enzyme, renin, upon its substrate and has been designated hypertensin I. It can be rapidly converted to a second approximately equally pressor compound, hypertensin II, apparently through the action of an enzyme in the plasma which requires halide or nitrate for activation. A highly purified preparation containing horse hypertensins I and II caused an elevation of blood pressure when injected into human beings.
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Metadata
- Authors
- Skeggs, L. T., Marsh, W. H., Kahn, J. R., & Shumway, N. P.
- Venue
- Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 1954-03-01
- Volume
- 99
- Issue
- 3
- Pages
- 275-282
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W1997934790
- Cited by
- 457
- References
- 0
- FWCI
- 13.75
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: THE EXISTENCE OF TWO FORMS OF HYPERTENSIN. https://app.cochat.ai/papers/10.1084/jem.99.3.275
- The paper
- Skeggs, L. T., Marsh, W. H., Kahn, J. R., & Shumway, N. P. (1954). THE EXISTENCE OF TWO FORMS OF HYPERTENSIN. Journal of Experimental Medicine. https://doi.org/10.1084/jem.99.3.275
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
