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Cited by 335

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Na, Cl, and Water Transport by Rat Ileum in Vitro

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Curran, Peter F.·1960·The Journal of General Physiology

Abstract

Interrelationships between metabolism, NaCl transport, and water transport have been studied in an in vitro preparation of rat ileum. When glucose is present in the mucosal solution, Na and Cl both appear to be actively transported from mucosa to serosa while water absorption is passive and dependent on net solute transport. Removal of glucose from the mucosal solution or treatment with dinitrophenol, monoiodoacetate, or anoxia inhibits active salt transport and as a result, water absorption is also inhibited. The dependence of water absorption on metabolism can be explained as a secondary effect due to its dependence on active salt transport. The relationship between salt and water transport has been discussed in terms of a model system.

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Metadata

Authors
Curran, P. F.
Venue
The Journal of General Physiology
Published
1960-07-01
Volume
43
Issue
6
Pages
1137-1148
ISSN
  • 0022-1295 (ISSN-L)
  • 1540-7748
OpenAlex
W2114172732
Cited by
335
References
0
FWCI
6.53
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Na, Cl, and Water Transport by Rat Ileum in Vitro. https://app.cochat.ai/papers/10.1085/jgp.43.6.1137
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Curran, P. F. (1960). Na, Cl, and Water Transport by Rat Ileum in Vitro. The Journal of General Physiology. https://doi.org/10.1085/jgp.43.6.1137

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.