Successful Treatment of Vancomycin-Resistant Enterococcus Endocarditis with Oral Linezolid
Abstract
We report a case of vancomycin-resistant Enterococcus faecium endocarditis that failed to respond to sequential monotherapy with chloramphenicol and quinupristin/dalfopristin but was successfully treated with oral linezolid.
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Cites
Chien, J. W., Kucia, M., & Salata, R. A. (2000) · Clinical Infectious Diseases · doi:10.1086/313597 · Cited by 192 · see citing works
The in-vitro activity of linezolid (U-100766) and tentative breakpoints
Wise, R. A., Andrews, J. M., Boswell, F. J., & Ashby, J. P. (1998) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/42.6.721 · Cited by 149 · see citing works
Rybak, M. J., Cappelletty, D. M., Moldovan, T., Aeschlimann, J. R., & Kaatz, G. W. (1998) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.42.3.721 · Cited by 147 · see citing works
Jones, R., Low, D., & Pfaller, M. A. (1999) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/s0732-8893(98)00108-4 · Cited by 126 · see citing works
Association Between Resistance to Vancomycin and Death in Cases of Enterococcus faecium Bacteremia
Garbutt, J. M., Ventrapragada, M., Littenberg, B., et al. (2000) · Clinical Infectious Diseases · doi:10.1086/313694 · Cited by 113 · see citing works
Matsumura, S., & Simor, A. E. (1998) · Clinical Infectious Diseases · doi:10.1086/517755 · Cited by 73 · see citing works
Bostic, G. D., Perri, M. B., Thal, L. A., et al. (1998) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/s0732-8893(97)00210-1 · Cited by 66 · see citing works
Noskin, G. A., Siddiqui, F., Stosor, V., Kruzynski, J., & Peterson, L. R. (1999) · Clinical Infectious Diseases · doi:10.1086/517221 · Cited by 60 · see citing works
McNeil, S., Clark, N. M., Chandrasekar, P. H., & Kauffman, C. A. (2000) · Clinical Infectious Diseases · doi:10.1086/313669 · Cited by 57 · see citing works
Aeschlimann, J. R., Zervos, M., & Rybak, M. J. (1998) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.42.10.2710 · Cited by 50 · see citing works
Furlong, W. B., & Rakowski, T. A. (1997) · Clinical Infectious Diseases · doi:10.1086/516895 · Cited by 45 · see citing works
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Research works printed but not linked: 1
- [7]7. Matsumara S, Simor E. Treatment of endocarditis with vancomycinresistant Enterococcus faecium with quinupristin/dalfopristin, doxycycline, and rifampin: a synergistic drug combination. Clin Infect Dis 1998 ; 27:1554-6.
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Baddour, L. M., Wilson, W. R., Bayer, A. S., Fowler, V. G., Tleyjeh, I. M., Rybak, M. J., Barsic, B., Lockhart, P. B., Gewitz, M. H., Levison, M. E., et al. (2015) · Circulation · doi:10.1161/cir.0000000000000296 · Cited by 3,232 · see citing works
Falagas, M. E. (2006) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkl219 · Cited by 167 · see citing works
Linezolid therapy for infective endocarditis
Muñoz, P., Rodríguez-Creixéms, M., Moreno, M., Marín, M., Ramallo, V., Bouza, E., & GAME Study Group (2007) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2006.01585.x · Cited by 68 · see citing works
Wareham, D. W., Abbas, H., Karcher, A. M., & Das, S. S. (2006) · Journal of Infection · doi:10.1016/j.jinf.2005.05.022 · Cited by 41 · see citing works
- Authors
- Babcock, H. M., Ritchie, D. J., Christiansen, E., Starlin, R., Little, R., & Stanley, S.
- Affiliations
- Washington University in St. Louis (US)
- Barnes-Jewish Hospital (US)
- Corresponding author
- Babcock, H. M.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-05-01
- Volume
- 32
- Issue
- 9
- Pages
- 1373-1375
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2106927934
- Semantic Scholar
- e9d9834d22bd6e3daccaf26dba218f9c706987f1
- Cited by
- 113
- References
- 11
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2022: 1 · 2021: 1 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 5 · 2014: 1 · 2013: 1 · 2012: 5
- FWCI
- 8.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Infective Endocarditis Diagnosis and Management
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Antibiotic Resistance in Bacteria
- Health Sciences › Medicine › Infectious Diseases › Antimicrobial Resistance in Staphylococcus
- Keywords
- vancomycin-resistant Enterococcus faecium, infective endocarditis, chloramphenicol, quinupristin/dalfopristin, antibiotic treatment failure
- MeSH terms
- Linezolid, Acetamides, Administration, Oral, Adult, Anti-Bacterial Agents, Endocarditis, Bacterial, Female, Follow-Up Studies, Humans, Treatment Outcome, Gram-Positive Bacterial Infections, Enterococcus faecium, Vancomycin Resistance, Oxazolidinones
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