The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
High Risk of Death Due to Bacterial and Fungal Infection among Cytomegalovirus (CMV)–Seronegative Recipients of Stem Cell Transplants from Seropositive Donors: Evidence for Indirect Effects of Primary CMV Infection
Abstract
The impact of cytomegalovirus (CMV) serostatus (seropositive [(+)] or seronegative [(-)]) of the donor (D) and recipient (R) on mortality after allogeneic non-T cell-depleted stem cell transplantation (SCT) in the era of preemptive therapy was assessed among 1750 patients by means of multivariable Cox regression models. In an analysis that included only pre-SCT variables, D(+)/R(+) and D(+)/R(-) patients had the highest risk for mortality. After neutropenia or the occurrence of CMV disease was controlled for, only D(+)/R(-) patients remained at a significantly higher risk for mortality. Mortality due to bacteremia or invasive fungal infection was higher among D(+)/R(-) (18.3%) than D(-)/R(-) (9.7%) patients (P <.001). Thus, CMV serostatus remains associated with mortality; neutropenia due to ganciclovir administration and CMV disease explain the association with mortality among seropositive recipients. However, in D(+)/R(-) subjects, mortality appears to be associated with bacterial and fungal infection, indicating a possible immunomodulatory effect of primary CMV infection that was undetected despite intensive monitoring.
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Citations
Cites
Principles and Practice of Infectious Diseases.
(1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-114-9-818_5 · Cited by 12,025
1994 Consensus Conference on Acute GVHD Grading.
Przepiorka, D., Weisdorf, D., Martin, P., Hg, K., Beatty, P., Hows, J., & Thomas, E. D. (1995) · PubMed · Cited by 5,037
Risk Factors for Cytomegalovirus Infection after Human Marrow Transplantation
Meyers, J. D., Flournoy, N., & Donnall Thomas, E. (1986) · Journal of Infectious Diseases · doi:10.1093/infdis/153.3.478 · Cited by 776
Valacyclovir for the Prevention of Cytomegalovirus Disease after Renal Transplantation
Lowance, D., Neumayer, H.-H., Legendre, C. M., Squifflet, J.-P., Kovarik, J., Brennan, P. J., Norman, D., Mendez, R., Keating, M. R., Coggon, G. L., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199905133401903 · Cited by 712
Ganciclovir Prophylaxis To Prevent Cytomegalovirus Disease after Allogeneic Marrow Transplant
Goodrich, J. M., Bowden, R. A., Fisher, L., Keller, C., Schoch, G., & Meyers†, J. D. (1993) · Annals of Internal Medicine · doi:10.7326/0003-4819-118-3-199302010-00003 · Cited by 650
Boeckh, M., Gooley, T., Myerson, D., Cunningham, T., Schoch, G., & Bowden, R. (1996) · Blood · doi:10.1182/blood.v88.10.4063.bloodjournal88104063 · Cited by 646
Self-citationBowden, R., Slichter, S., Sayers, M., Weisdorf, D., Cays, M., Schoch, G., Banaji, M., Haake, R., Welk, K., & Fisher, L. (1995) · Blood · doi:10.1182/blood.v86.9.3598.bloodjournal8693598 · Cited by 630
Schmidt, G. M., Horak, D. A., Niland, J. C., Duncan, S. R., Forman, S. J., Zaia, J. A., & the City of Hope–Stanford–Syntex CMV Study Group* (1991) · New England Journal of Medicine · doi:10.1056/nejm199104113241501 · Cited by 616
(2000) · Biology of Blood and Marrow Transplantation · doi:10.1016/s1083-8791(00)70002-4 · Cited by 607
Goodrich, J. M., Mori, M., Gleaves, C. A., Du Mond, C., Cays, M., Ebeling, D. F., Buhles, W. C., DeArmond, B., & Meyers, J. D. (1991) · New England Journal of Medicine · doi:10.1056/nejm199112053252303 · Cited by 599
Cited by
Marr, K. A., Carter, R. A., Boeckh, M., Martin, P., & Corey, L. (2002) · Blood · doi:10.1182/blood-2002-05-1496 · Cited by 957
Self-citationTeira, P., Battiwalla, M., Ramanathan, M., Barrett, A. J., Ahn, K. W., Chen, M., Green, J. S., Saad, A., Antin, J. H., Savani, B. N., et al. (2016) · Blood · doi:10.1182/blood-2015-11-679639 · Cited by 553
Self-citationQuantitative Temporal Viromics: An Approach to Investigate Host-Pathogen Interaction
Weekes, M. P., Tomasec, P., Huttlin, E. L., Fielding, C. A., Nusinow, D., Stanton, R. J., Wang, E. C. Y., Aicheler, R., Murrell, I., Wilkinson, G. W. G., et al. (2014) · Cell · doi:10.1016/j.cell.2014.04.028 · Cited by 431
Boeckh, M., Nichols, W. G., Papanicolaou, G., Rubin, R., Wingard, J. R., & Zaia, J. (2003) · Biology of Blood and Marrow Transplantation · doi:10.1016/s1083-8791(03)00287-8 · Cited by 431
Self-citationSÖDERBERG‐NAUCLÉR, C. (2006) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2006.01618.x · Cited by 349
Metadata
- Authors
- Nichols, W. G., Corey, L., Gooley, T., Davis, C., & Boeckh, M.
- Venue
- The Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-02
- Volume
- 185
- Issue
- 3
- Pages
- 273-282
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2164200647
- Cited by
- 422
- References
- 37
- FWCI
- 8.56
- Type
- journal article
- Language
- en
- Open access
- closed
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- Nichols, W. G., Corey, L., Gooley, T., Davis, C., & Boeckh, M. (2002). High Risk of Death Due to Bacterial and Fungal Infection among Cytomegalovirus (CMV)–Seronegative Recipients of Stem Cell Transplants from Seropositive Donors: Evidence for Indirect Effects of Primary CMV Infection. The Journal of Infectious Diseases. https://doi.org/10.1086/338624
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