The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Surgical Site Infections in Orthopedic Surgery: The Effect of Mupirocin Nasal Ointment in a Double‐Blind, Randomized, Placebo‐Controlled Study
Open accessAbstract
The objective of this study was to determine whether use of mupirocin nasal ointment for perioperative eradication of Staphylococcus aureus nasal carriage is effective in preventing the development of surgical site infections (SSIs). A randomized, double-blind, placebo-controlled design was used. Either mupirocin or placebo nasal ointment was applied twice daily to 614 assessable patients from the day of admission to the hospital until the day of surgery. A total of 315 and 299 patients were randomized to receive mupirocin and placebo, respectively. Eradication of nasal carriage was significantly more effective in the mupirocin group (eradication rate, 83.5% versus 27.8%). In the mupirocin group, the rate of endogenous S. aureus infections was 5 times lower than in the placebo group (0.3% and 1.7%, respectively; relative risk, 0.19; 95% confidence interval, 0.02-1.62). Mupirocin nasal ointment did not reduce the SSI rate (by S. aureus) or the duration of hospital stay.
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Cites
Nasal Carriage as a Source of Staphylococcus aureus Bacteremia
von Eiff, C., Becker, K., Machka, K., Stammer, H., & Peters, G. (2001) · New England Journal of Medicine · doi:10.1056/nejm200101043440102 · Cited by 1,984
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The role of nasal carriage in Staphylococcus aureus infections
Wertheim, H. F., Melles, D. C., Vos, M. C., van Leeuwen, W., van Belkum, A., Verbrugh, H. A., & Nouwen, J. L. (2005) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(05)70295-4 · Cited by 2,685
Clinical practice guidelines for antimicrobial prophylaxis in surgery
Bratzler, D. W., Dellinger, E. P., Olsen, K. M., Perl, T. M., Auwaerter, P. G., Bolon, M. K., Fish, D. N., Napolitano, L. M., Sawyer, R. G., Slain, D., et al. (2013) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp120568 · Cited by 2,591
Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery
Bratzler, D. W., Dellinger, E. P., Olsen, K. M., Perl, T. M., Auwaerter, P. G., Bolon, M. K., Fish, D. N., Napolitano, L. M., Sawyer, R. G., Slain, D., et al. (2013) · Surgical Infections · doi:10.1089/sur.2013.9999 · Cited by 1,197
Allegranzi, B., Bischoff, P., de Jonge, S., Kubilay, N. Z., Zayed, B., Gomes, S. M., Abbas, M., Atema, J. J., Gans, S., van Rijen, M., et al. (2016) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(16)30398-x · Cited by 908
Self-citationNasal Carriage of Staphylococcus aureus and Prevention of Nosocomial Infections
Kluytmans, J. A. J. W., & Wertheim, H. F. L. (2005) · Infection · doi:10.1007/s15010-005-4012-9 · Cited by 360
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Metadata
- Authors
- Kalmeijer, M. D., Coertjens, H., van Nieuwland‐Bollen, P. M., Bogaers‐Hofman, D., de Baere, G. A. J., Stuurman, A., van Belkum, A., & Kluytmans, J. A. J. W.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-08-15
- Volume
- 35
- Issue
- 4
- Pages
- 353-358
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2107764056
- Cited by
- 348
- References
- 1
- FWCI
- 12.40
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Kalmeijer, M. D., Coertjens, H., van Nieuwland‐Bollen, P. M., Bogaers‐Hofman, D., de Baere, G. A. J., Stuurman, A., van Belkum, A., & Kluytmans, J. A. J. W. (2002). Surgical Site Infections in Orthopedic Surgery: The Effect of Mupirocin Nasal Ointment in a Double‐Blind, Randomized, Placebo‐Controlled Study. Clinical Infectious Diseases. https://doi.org/10.1086/341025
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
