The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Outcome of and Prognostic Factors for Herpes Simplex Encephalitis in Adult Patients: Results of a Multicenter Study
Abstract
Management of herpes simplex encephalitis (HSE) has been considerably improved by the availability of acyclovir therapy and rapid polymerase chain reaction (PCR)-based diagnostic assays. Prognostic factors for this rare affliction are, however, misestimated. We conducted a large retrospective multicenter study that included 93 adult patients in whom HSE was diagnosed by PCR from 1991 through 1998 and who were treated with intravenous acyclovir. Among the 85 patients assessed at 6 months, 30 (35%) had a poor outcome, which led to death in 13 patients (15%) and severe disability in 17 (20%). The outcome was favorable for 55 patients (65%). A multivariate analysis identified 2 factors that were found to be independently associated with poor outcome: a Simplified Acute Physiology Score II >/=27 at admission and a delay of >2 days between admission to the hospital and initiation of acyclovir therapy. Early administration of antiviral therapy is the only parameter that can be modified to improve the prognosis of patients with HSE.
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Cites
ASSESSMENT OF COMA AND IMPAIRED CONSCIOUSNESS
Teasdale, G., & Jennett, B. (1974) · The Lancet · doi:10.1016/s0140-6736(74)91639-0 · Cited by 13,215
Vidarabine versus Acyclovir Therapy in Herpes Simplex Encephalitis
Whitley, R. J., Alford, C. A., Hirsch, M. S., Schooley, R. T., Luby, J. P., Aoki, F. Y., Hanley, D., Nahmias, A. J., Soong, S.-J., & The NIAID Collaborative Antiviral Study Group* (1986) · New England Journal of Medicine · doi:10.1056/nejm198601163140303 · Cited by 896
ACYCLOVIR VERSUS VIDARABINE IN HERPES SIMPLEX ENCEPHALITIS
Sköldenberg, B., Alestig, K., Burman, L., Forkman, A., Lövgren, K., Norrby, R., Stiernstedt, G., Forsgren, M., Bergström, T., Dahlqvist, E., et al. (1984) · The Lancet · doi:10.1016/s0140-6736(84)92623-0 · Cited by 610
Herpes simplex encephalitis: long term magnetic resonance imaging and neuropsychological profile.
Kapur, N., Barker, S., Burrows, E. H., Ellison, D., Brice, J., Illis, L. S., Scholey, K., Colbourn, C., Wilson, B., & Loates, M. (1994) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.57.11.1334 · Cited by 224
Cited by
Tunkel, A. R., Glaser, C. A., Bloch, K. C., Sejvar, J. J., Marra, C. M., Roos, K. L., Hartman, B. J., Kaplan, S. L., Scheld, W. M., & Whitley, R. J. (2008) · Clinical Infectious Diseases · doi:10.1086/589747 · Cited by 1,193
(2014) · Handbook of Clinical Neurology · doi:10.1016/b978-0-444-53488-0.00011-0 · Cited by 474
N‐methyl‐ D ‐aspartate receptor antibodies in herpes simplex encephalitis
Prüss, H., Finke, C., Höltje, M., Hofmann, J., Klingbeil, C., Probst, C., Borowski, K., Ahnert‐Hilger, G., Harms, L., Schwab, J. M., et al. (2012) · Annals of Neurology · doi:10.1002/ana.23689 · Cited by 422
Encephalitis hospitalization rates and inpatient mortality in the United States, 2000-2010
George, B. P., Schneider, E. B., & Venkatesan, A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104169 · Cited by 263
McGill, F., Heyderman, R. S., Michael, B. D., Defres, S., Beeching, N. J., Borrow, R., Glennie, L., Gaillemin, O., Wyncoll, D., Kaczmarski, E., et al. (2016) · Journal of Infection · doi:10.1016/j.jinf.2016.01.007 · Cited by 254
Metadata
- Authors
- Raschilas, F., Wolff, M., Delatour, F., Chaffaut, C., De Broucker, T., Chevret, S., Lebon, P., Canton, P., Rozenberg, F., & French Herpes Simplex Encephalitis Study Group
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-08
- Volume
- 35
- Issue
- 3
- Pages
- 254-260
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2050114111
- Cited by
- 528
- References
- 4
- FWCI
- 5.23
- Type
- journal article
- Language
- en
- Open access
- closed
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- Raschilas, F., Wolff, M., Delatour, F., Chaffaut, C., De Broucker, T., Chevret, S., Lebon, P., Canton, P., Rozenberg, F., & French Herpes Simplex Encephalitis Study Group. (2002). Outcome of and Prognostic Factors for Herpes Simplex Encephalitis in Adult Patients: Results of a Multicenter Study. Clinical Infectious Diseases. https://doi.org/10.1086/341405
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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