The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
High Circulating Levels of the Dengue Virus Nonstructural Protein NS1 Early in Dengue Illness Correlate with the Development of Dengue Hemorrhagic Fever
Abstract
Infection with any 1 of 4 dengue viruses produces a spectrum of clinical illness ranging from a mild undifferentiated febrile illness to dengue fever (DF) to dengue hemorrhagic fever (DHF), a potentially life-threatening disease. The morbidity and mortality of DHF can be reduced by early hospitalization and careful supportive care. To determine its usefulness as a predictor of DHF, plasma levels of the secreted dengue virus nonstructural protein NS1 (sNS1) were measured daily in 32 children with dengue-2 virus infections participating in a prospective, hospital-based study. Free sNS1 levels in plasma correlated with viremia levels and were higher in patients with DHF than in those with DF. An elevated free sNS1 level (> or =600 ng/mL) within 72 h of illness onset identified patients at risk for developing DHF.
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Citations
Cites
Pathophysiologic and Prognostic Role of Cytokines in Dengue Hemorrhagic Fever
Bethell, D. B., Flobbe, K., Phuong, C. X. T., Day, N. P. J., Phuong, P. T., Buurman, W. A., Cardosa, M. J., White, N. J., & Kwiatkowski, D. (1998) · The Journal of Infectious Diseases · doi:10.1086/517807 · Cited by 180
Cited by
Dengue virus life cycle: viral and host factors modulating infectivity
Rodenhuis-Zybert, I. A., Wilschut, J., & Smit, J. M. (2010) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-010-0357-z · Cited by 499
A Randomized Controlled Trial of Chloroquine for the Treatment of Dengue in Vietnamese Adults
Tricou, V., Minh, N. N., Van, T. P., Lee, S. J., Farrar, J., Wills, B., Tran, H. T., & Simmons, C. P. (2010) · PLoS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0000785 · Cited by 329
Azeredo, E. L. D., Monteiro, R. Q., & de-Oliveira Pinto, L. M. (2015) · Mediators of Inflammation · doi:10.1155/2015/313842 · Cited by 288
Whitehorn, J., & Simmons, C. P. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.07.022 · Cited by 282
Immune-mediated cytokine storm and its role in severe dengue
Srikiatkhachorn, A., Mathew, A., & Rothman, A. L. (2017) · Seminars in Immunopathology · doi:10.1007/s00281-017-0625-1 · Cited by 267
Self-citation
Metadata
- Authors
- Libraty, D. H., Young, P. R., Pickering, D., Endy, T. P., Kalayanarooj, S., Green, S., Vaughn, D. W., Nisalak, A., Ennis, F. A., & Rothman, A. L.
- Venue
- The Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-10-15
- Volume
- 186
- Issue
- 8
- Pages
- 1165-1168
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2146006596
- Cited by
- 739
- References
- 1
- FWCI
- 5.33
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Libraty, D. H., Young, P. R., Pickering, D., Endy, T. P., Kalayanarooj, S., Green, S., Vaughn, D. W., Nisalak, A., Ennis, F. A., & Rothman, A. L. (2002). High Circulating Levels of the Dengue Virus Nonstructural Protein NS1 Early in Dengue Illness Correlate with the Development of Dengue Hemorrhagic Fever. The Journal of Infectious Diseases. https://doi.org/10.1086/343813
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
