The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Web Resources for HIV Type 1 Genotypic-Resistance Test Interpretation
Open accessAbstract
Interpreting the results of plasma human immunodeficiency virus type 1 (HIV-1) genotypic drug-resistance tests is one of the most difficult tasks facing clinicians caring for HIV-1-infected patients. There are many drug-resistance mutations, and they arise in complex patterns that cause varying levels of drug resistance. In addition, HIV-1 exists in vivo as a virus population containing many genomic variants. Genotypic-resistance testing detects the drug-resistance mutations present in the most common plasma virus variants but may not detect drug-resistance mutations present in minor virus variants. Therefore, interpretation systems are necessary to determine the phenotypic and clinical significance of drug-resistance mutations found in a patient's plasma virus population. We describe the scientific principles of HIV-1 genotypic-resistance test interpretation and the most commonly used Web-based resources for clinicians ordering genotypic drug-resistance tests.
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Cites
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Metadata
- Authors
- Liu, T. F., & Shafer, R. W.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-06-01
- Volume
- 42
- Issue
- 11
- Pages
- 1608-1618
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2154164013
- Cited by
- 654
- References
- 19
- FWCI
- 5.16
- Type
- journal article
- Language
- en
- Open access
- bronze
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