The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Rationale and Uses of a Public HIV Drug‐Resistance Database
Open accessAbstract
Knowledge regarding the drug resistance of human immunodeficiency virus (HIV) is critical for surveillance of drug resistance, development of antiretroviral drugs, and management of infections with drug-resistant viruses. Such knowledge is derived from studies that correlate genetic variation in the targets of therapy with the antiretroviral treatments received by persons from whom the variant was obtained (genotype-treatment), with drug-susceptibility data on genetic variants (genotype-phenotype), and with virological and clinical response to a new treatment regimen (genotype-outcome). An HIV drug-resistance database is required to represent, store, and analyze the diverse forms of data underlying our knowledge of drug resistance and to make these data available to the broad community of researchers studying drug resistance in HIV and clinicians using HIV drug-resistance tests. Such genotype-treatment, genotype-phenotype, and genotype-outcome correlations are contained in the Stanford HIV RT and Protease Sequence Database and have specific usefulness.
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Hammer, S. M., Squires, K. E., Hughes, M. D., Grimes, J. M., Demeter, L. M., Currier, J. S., Eron, J. J., Feinberg, J. E., Balfour, H. H., Deyton, L. R., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199709113371101 · Cited by 2,640
Human Immunodeficiency Virus Reverse Transcriptase and Protease Sequence Database
Shafer, R. W., Stevenson, D., & Chan, B. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.1.348 · Cited by 907
Self-citationHuman immunodeficiency virus reverse transcriptase and protease sequence database
Rhee, S.-Y. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg100 · Cited by 817
Clavel, F., & Hance, A. J. (2004) · New England Journal of Medicine · doi:10.1056/nejm2ra025195 · Cited by 800
Hirsch, M. S., Brun‐Vezinet, F., Clotet, B., Conway, B., Kuritzkes, D. R., D’Aquila, R. T., Demeter, L. M., Hammer, S. M., Johnson, V. A., Loveday, C., et al. (2003) · Clinical Infectious Diseases · doi:10.1086/375597 · Cited by 514
Weidle, P. J., Malamba, S., Mwebaze, R., Sozi, C., Rukundo, G., Downing, R., Hanson, D., Ochola, D., Mugyenyi, P., Mermin, J., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)09330-3 · Cited by 315
Laurent, C., Kouanfack, C., Koulla-Shiro, S., Nkoué, N., Bourgeois, A., Calmy, A., Lactuock, B., Nzeusseu, V., Mougnutou, R., Peytavin, G., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16586-0 · Cited by 309
Nelfinavir, Efavirenz, or Both after the Failure of Nucleoside Treatment of HIV Infection
Albrecht, M., Bosch, R. J., Hammer, S. M., Liou, S.-H., Kessler, H. A., Para, M. F., Eron, J. J., Valdez, H., Dehlinger, M., & Katzenstein, D. A. (2001) · New England Journal of Medicine · doi:10.1056/nejm200108093450602 · Cited by 122
Pillay, D., Walker, A. S., Gibb, D. M., Rossi, A. D., Kaye, S., Ait‐Khaled, M., Muñoz‐Fernández, M. Á., Babiker, A. G., & Paediatric European Network for Treatment of AIDS (PENTA) (2002) · The Journal of Infectious Diseases · doi:10.1086/342680 · Cited by 91
Kebba, A., Atwine, D., Mwebaze, R. M., Kityo, C. M., Nakityo, R., & Peter, M. (2002) · AIDS Research and Human Retroviruses · doi:10.1089/08892220260387922 · Cited by 39
Cited by
Clinical and biological insights from viral genome sequencing
Houldcroft, C. J., Beale, M. A., & Breuer, J. (2017) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2016.182 · Cited by 334
Drug databases and their contributions to drug repurposing
Masoudi-Sobhanzadeh, Y., Omidi, Y., Amanlou, M., & Masoudi-Nejad, A. (2020) · Genomics · doi:10.1016/j.ygeno.2019.06.021 · Cited by 131
Structural basis of second-generation HIV integrase inhibitor action and viral resistance
Cook, N. J., Li, W., Berta, D., Badaoui, M., Ballandras-Colas, A., Nans, A., Kotecha, A., Rosta, E., Engelman, A. N., & Cherepanov, P. (2020) · Science · doi:10.1126/science.aay4919 · Cited by 108
Byun, H., Papathanasopoulos, M. A., Steegen, K., & Basson, A. E. (2024) · Viruses · doi:10.3390/v16121888 · Cited by 5
Metadata
- Authors
- Shafer, R. W.
- Venue
- The Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-09-15
- Volume
- 194
- Issue
- s1
- Pages
- S51-S58
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2169790816
- Cited by
- 414
- References
- 11
- FWCI
- 2.87
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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