Cited by 869Herpesvirus Infections and TreatmentsCytomegalovirus and herpesvirus researchViral Infections and Immunology Research

The DOI matches its Crossref record; 251 of the 253 references it cites were found in a registry or an index.

Recommendations for the Management of Herpes Zoster

Abstract

The objective of this article is to provide evidence-based recommendations for the management of patients with herpes zoster (HZ) that take into account clinical efficacy, adverse effects, impact on quality of life, and costs of treatment. Systematic literature reviews, published randomized clinical trials, existing guidelines, and the authors' clinical and research experience relevant to the management of patients with HZ were reviewed at a consensus meeting. The results of controlled trials and the clinical experience of the authors support the use of acyclovir, brivudin (where available), famciclovir, and valacyclovir as first-line antiviral therapy for the treatment of patients with HZ. Specific recommendations for the use of these medications are provided. In addition, suggestions are made for treatments that, when used in combination with antiviral therapy, may further reduce pain and other complications of HZ.

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Crossref · 10.1086/510206

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Show all 253 references

Research works printed but not linked: 10

  1. Rowbotham, 2001, Spectrum of pain mechanisms contributing to PHN, 183
  2. Johnson, 2002, Improving the management of varicella, herpes zoster and zoster-associated pain. Recommendations from the IHMF Management Strategies Workshop
  3. Dworkin, 2005, Strategies for the prevention of neuropathic pain, 39
  4. Brentjens, Reduction of postherpetic neuralgia in herpes zoster: a study of the effects of gabapentin with valacyclovir during acute zoster outbreaks
  5. Rowbotham, 2004, Pregabalin significantly reduces neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia by day 3 of treatment, 48
  6. Brentjens, A double-blind randomized study of the use of 2 grams vs. 1 gram valacyclovir TID for 7 days in the treatment of acute herpes zoster in immunocompromised individuals
  7. Sullivan, Famciclovir in the management of acute herpes zoster in HIV+ patients
  8. Ragozzino, 1982, Population-based study of herpes zoster and its sequelae, Medicine, 61, 310, 10.1097/00005792-198209000-00003 · DOI
  9. Oxman, Efficacy of zoster vaccine according to dermatome region
  10. Pavan-Langston, 2005, Viral disease of the ocular anterior segment: basic science and clinical disease, 297

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Metadata

Authors
Dworkin, R. H., Johnson, R. W., Breuer, J., Gnann, J. W., Levin, M. J., Backonja, M., Betts, R. F., Gershon, A. A., Haanpää, M. L., McKendrick, M. W., Nurmikko, T. J., Oaklander, A. L., Oxman, M. N., Langston, D. P., Petersen, K. L., Rowbotham, M. C., Schmader, K. E., Stacey, B. R., Tyring, S. K., Wijck, A. J. M. V., Wallace, M. S., Wassilew, S. W., & Whitley, R. J.
Affiliations
  • University of Rochester Medicine (US)
  • University of Bristol (GB)
  • Queen Mary University of London (GB)
  • Birmingham VA Medical Center (US)
  • University of Colorado Denver (US)
  • Columbia University (US)
  • Helsinki University Hospital (FI)
  • Royal Hallamshire Hospital (GB)
  • University of Liverpool (GB)
  • Harvard University (US)
  • University of California San Diego (US)
  • University of California, San Francisco (US)
  • Duke University (US)
  • The University of Texas Health Science Center at Houston (US)
  • Utrecht University (NL)
  • Helios Klinikum Krefeld (DE)
  • University of Alabama at Birmingham (US)
Corresponding author
Dworkin, Robert H.
Venue
Clinical Infectious Diseases
Published
2007-01-01
Volume
44
Issue
Supplement_1
Pages
S1-S26
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W2104761404
Cited by
869
References
253
Citations by year
2026: 34 · 2025: 39 · 2024: 48 · 2023: 51 · 2022: 51 · 2021: 46 · 2020: 46 · 2019: 37 · 2018: 48 · 2017: 52 · 2016: 43 · 2015: 46 · 2014: 50 · 2013: 52 · 2012: 43
FWCI
24.59
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Infectious Diseases (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
  • HighWire Press Open Archive (submittedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Herpesvirus Infections and Treatments
  • Health Sciences › Medicine › Epidemiology › Cytomegalovirus and herpesvirus research
  • Health Sciences › Medicine › Infectious Diseases › Viral Infections and Immunology Research
Keywords
herpes zoster, antiviral therapy, acyclovir, brivudin, famciclovir, valacyclovir, first-line therapy, postherpetic neuralgia, treatment guidelines, treatment costs, quality of life
MeSH terms
Valacyclovir, Famciclovir, Acyclovir, Analgesics, Anti-Inflammatory Agents, Antiviral Agents, Bromodeoxyuridine, Herpes Zoster, Humans, Immunocompetence, Valine, Herpesvirus 3, Human, 2-Aminopurine, Immunocompromised Host

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