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Cited by 543

The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.

Prevalence and Risk Factors for Human Papillomavirus Infection of the Anal Canal in Human Immunodeficiency Virus (HIV)‐Positive and HIV‐Negative Homosexual Men

Palefsky, Joel M., Holly, Elizabeth A., Ralston, Mary L., Jay, Naomi·1998·The Journal of Infectious Diseases

Abstract

One of the groups at highest risk of anal cancer is homosexual and bisexual men. Like cervical cancer, anal cancer is associated with human papillomavirus (HPV) infection. Anal HPV infection was characterized in a study of 346 human immunodeficiency virus (HIV)-positive and 262 HIV-negative homosexual and bisexual men. Anal HPV DNA was detected in 93% of HIV-positive and 61% of HIV-negative men by polymerase chain reaction. The spectrum of HPV types was similar in HIV-positive and HIV-negative men, with HPV-16 the most common type. Infection with multiple HPV types was found in 73% of HIV-positive and 23% of HIV-negative men. Among HIV-positive men who were positive by hybrid capture for group B HPV types (16/18/31/33/35/39/45/51/52/56/58) or group A types (6/11/42/43/44), lower CD4 cell levels were associated with higher levels of group B DNA (P = .004) but not group A DNA. These data suggest increased replication of the more oncogenic HPV types with more advanced immunosuppression.

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Metadata

Authors
Palefsky, J. M., Holly, E. A., Ralston, M. L., & Jay, N.
Venue
The Journal of Infectious Diseases
Published
1998-02
Volume
177
Issue
2
Pages
361-367
ISSN
  • 0022-1899 (ISSN-L)
  • 1537-6613
OpenAlex
W2106993950
Cited by
543
References
16
FWCI
11.67
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Prevalence and Risk Factors for Human Papillomavirus Infection of the Anal Canal in Human Immunodeficiency Virus (HIV)‐Positive and HIV‐Negative Homosexual Men. https://app.cochat.ai/papers/10.1086/514194
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Palefsky, J. M., Holly, E. A., Ralston, M. L., & Jay, N. (1998). Prevalence and Risk Factors for Human Papillomavirus Infection of the Anal Canal in Human Immunodeficiency Virus (HIV)‐Positive and HIV‐Negative Homosexual Men. The Journal of Infectious Diseases. https://doi.org/10.1086/514194

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