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The Reemergence of Ebola Hemorrhagic Fever, Democratic Republic of the Congo, 1995

Open access
Khan, Ali S., Tshioko, F. Kweteminga, Heymann, David L., Le Guenno, Bernard, Nabeth, Pierre, Kerstiëns, Barbara, Fleerackers, Yon, Kilmarx, Peter H., Rodier, Guenael R., Nkuku, Okumi, Rollin, Pierre E., Sanchez, Anthony, Zaki, Sherif R., Swanepoel, Robert, Tomori, Oyewale, Nichol, Stuart T., Peters, C. J., Muyembe‐Tamfum, J. J., Ksiazek, Thomas G., the Commission de Lutte contre les Epidémies à Kikwit·1999·The Journal of Infectious Diseases

Abstract

In May 1995, an international team characterized and contained an outbreak of Ebola hemorrhagic fever (EHF) in Kikwit, Democratic Republic of the Congo. Active surveillance was instituted using several methods, including house-to-house search, review of hospital and dispensary logs, interview of health care personnel, retrospective contact tracing, and direct follow-up of suspect cases. In the field, a clinical case was defined as fever and hemorrhagic signs, fever plus contact with a case-patient, or fever plus at least 3 of 10 symptoms. A total of 315 cases of EHF, with an 81% case fatality, were identified, excluding 10 clinical cases with negative laboratory results. The earliest documented case-patient had onset on 6 January, and the last case-patient died on 16 July. Eighty cases (25%) occurred among health care workers. Two individuals may have been the source of infection for >50 cases. The outbreak was terminated by the initiation of barrier-nursing techniques, health education efforts, and rapid identification of cases.

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Metadata

Authors
Khan, A. S., Tshioko, F. K., Heymann, D. L., Le Guenno, B., Nabeth, P., Kerstiëns, B., Fleerackers, Y., Kilmarx, P. H., Rodier, G. R., Nkuku, O., Rollin, P. E., Sanchez, A., Zaki, S. R., Swanepoel, R., Tomori, O., Nichol, S. T., Peters, C. J., Muyembe‐Tamfum, J. J., Ksiazek, T. G., & the Commission de Lutte contre les Epidémies à Kikwit
Venue
The Journal of Infectious Diseases
Published
1999-02
Volume
179
Issue
s1
Pages
S76-S86
ISSN
  • 0022-1899 (ISSN-L)
  • 1537-6613
OpenAlex
W2141568825
Cited by
463
References
0
FWCI
9.78
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The Reemergence of Ebola Hemorrhagic Fever, Democratic Republic of the Congo, 1995. https://app.cochat.ai/papers/10.1086/514306
The paper
Khan, A. S., Tshioko, F. K., Heymann, D. L., Le Guenno, B., Nabeth, P., Kerstiëns, B., Fleerackers, Y., Kilmarx, P. H., Rodier, G. R., Nkuku, O., Rollin, P. E., Sanchez, A., Zaki, S. R., Swanepoel, R., Tomori, O., Nichol, S. T., Peters, C. J., Muyembe‐Tamfum, J. J., Ksiazek, T. G., & the Commission de Lutte contre les Epidémies à Kikwit. (1999). The Reemergence of Ebola Hemorrhagic Fever, Democratic Republic of the Congo, 1995. The Journal of Infectious Diseases. https://doi.org/10.1086/514306

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.