Super-spreaders in infectious diseases
Open accessAbstract
Early studies that explored host-pathogen interactions assumed that infected individuals within a population have equal chances of transmitting the infection to others. Subsequently, in what became known as the 20/80 rule, a small percentage of individuals within any population was observed to control most transmission events. This empirical rule was shown to govern inter-individual transmission dynamics for many pathogens in several species, and individuals who infect disproportionately more secondary contacts, as compared to most others, became known as super-spreaders. Studies conducted in the wake of the severe acute respiratory syndrome (SARS) pandemic revealed that, in the absence of super-spreading events, most individuals infect few, if any, secondary contacts. The analysis of SARS transmission, and reports from other outbreaks, unveil a complex scenario in which super-spreading events are shaped by multiple factors, including co-infection with another pathogen, immune suppression, changes in airflow dynamics, delayed hospital admission, misdiagnosis, and inter-hospital transfers. Predicting and identifying super-spreaders open significant medical and public health challenges, and represent important facets of infectious disease management and pandemic preparedness plans.
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Cites
A Major Outbreak of Severe Acute Respiratory Syndrome in Hong Kong
Lee, N. L. S., Hui, D. S. C., Wu, A. K. L., Chan, P. K. S., Cameron, P. A., Joynt, G. M., Ahuja, A. T., Yung, M. Y., Leung, C. B., To, K. F., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030685 · Cited by 2,631 · see citing works
Superspreading and the effect of individual variation on disease emergence
Lloyd-Smith, J. O., Schreiber, S. J., Kopp, P. E., & Getz, W. M. (2005) · Nature · doi:10.1038/nature04153 · Cited by 2,514 · see citing works
Transmission Dynamics and Control of Severe Acute Respiratory Syndrome
Lipsitch, M., Cohen, T., Cooper, B. S., Robins, J. M., Ma, S., James, L., Gopalakrishna, G., Chew, S. K., Tan, C. C., Samore, M. H., et al. (2003) · Science · doi:10.1126/science.1086616 · Cited by 1,467 · see citing works
Evidence of Airborne Transmission of the Severe Acute Respiratory Syndrome Virus
Yu, I. T. S., Li, Y., Wong, T. W., Tam, W., Chan, A., Lee, J. H. W., Leung, D. Y. C., & Ho, T. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032867 · Cited by 1,255 · see citing works
Perspectives on the basic reproductive ratio
Heffernan, J. M., Smith, R. J., & Wahl, L. M. (2005) · Journal of The Royal Society Interface · doi:10.1098/rsif.2005.0042 · Cited by 1,232 · see citing works
Woolhouse, M. E. J., Dye, C., Etard, J.-F., Smith, T., Charlwood, J. D., Garnett, G. P., Hagan, P., Hii, J. L. K., Ndhlovu, P. D., Quinnell, R. J., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.1.338 · Cited by 1,194 · see citing works
Riley, S., Fraser, C., Donnelly, C. A., Ghani, A. C., Abu-Raddad, L. J., Hedley, A. J., Leung, G. M., Ho, L., Lam, T.-H., Thach, T., et al. (2003) · Science · doi:10.1126/science.1086478 · Cited by 1,152 · see citing works
Cohen, M. S., Hoffman, I., Royce, R. A., Kazembe, P. N., Dyer, J. R., Daly, C. C., Zimba, D., Vernazza, P., Maida, M., Fiscus, S. A., et al. (1997) · The Lancet · doi:10.1016/s0140-6736(97)02190-9 · Cited by 873 · see citing works
Host heterogeneity dominates West Nile virus transmission
Marm Kilpatrick, A., Daszak, P., Jones, M. J., Marra, P. P., & Kramer, L. D. (2006) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2006.3575 · Cited by 533 · see citing works
The Reemergence of Ebola Hemorrhagic Fever, Democratic Republic of the Congo, 1995
Khan, A. S., Tshioko, F. K., Heymann, D. L., Guenno, B. L., Nabeth, P., Kerstiëns, B., Fleerackers, Y., Kilmarx, P. H., Rodier, G. R., Nkuku, O. B., et al. (1999) · The Journal of Infectious Diseases · doi:10.1086/514306 · Cited by 462 · see citing works
Reduction of HIV-1 RNA Levels with Therapy to Suppress Herpes Simplex Virus
Nagot, N., Ouédraogo, A., Foulongne, V., Konaté, I., Weiss, H. A., Vergne, L., Defer, M.-C., Djagbare, D., Sanon, A., Andonaba, J. B., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa062607 · Cited by 385 · see citing works
Modeling influenza epidemics and pandemics: insights into the future of swine flu (H1N1)
Coburn, B. J., Wagner, B. G., & Blower, S. M. (2009) · BMC Medicine · doi:10.1186/1741-7015-7-30 · Cited by 374 · see citing works
Concentration and Prevalence of Escherichia coli O157 in Cattle Feces at Slaughter
Omisakin, F., MacRae, M., Ogden, I. D., & Strachan, N. J. C. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.5.2444-2447.2003 · Cited by 310 · see citing works
Lawley, T. D., Bouley, D. M., Hoy-Schulz, Y. E., Gerke, C., Relman, D. A., & Monack, D. M. (2007) · Infection and Immunity · doi:10.1128/iai.01189-07 · Cited by 307 · see citing works
Superspreading SARS events, Beijing, 2003
Shen, Z., Ning, F., Zhou, W., He, X., Lin, C., Chin, D. P., Zhu, Z., & Schuchat, A. (2004) · Emerging Infectious Diseases · doi:10.3201/eid1002.030732 · Cited by 280 · see citing works
Heterogeneous shedding of Escherichia coli O157 in cattle and its implications for control
Matthews, L., Low, J. C., Gally, D. L., Pearce, M. C., Mellor, D. J., Heesterbeek, H., Chase-Topping, M. E., Naylor, S. W., Shaw, D. J., Reid, S. W. J., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503776103 · Cited by 257 · see citing works
A Cloud Adult: The Staphylococcus aureus-Virus Interaction Revisited
Sherertz, R. J., Reagan, D. R., Hampton, K. D., Robertson, K. L., Streed, S. A., Hoen, H. M., Thomas, R. M., & Gwaltney, J. M. (1996) · Annals of Internal Medicine · doi:10.7326/0003-4819-124-6-199603150-00001 · Cited by 215 · see citing works
Outbreak of Tuberculosis among Regular Patrons of a Neighborhood Bar
Kline, S. E., Hedemark, L. L., & Davies, S. F. (1995) · New England Journal of Medicine · doi:10.1056/nejm199507273330404 · Cited by 207 · see citing works
Extensive Transmission ofMycobacterium tuberculosisfrom a Child
Curtis, A. B., Ridzon, R., Vogel, R., McDonough, S. L., Hargreaves, J., Ferry, J., Valway, S. E., & Onorato, I. M. (1999) · New England Journal of Medicine · doi:10.1056/nejm199911113412002 · Cited by 196 · see citing works
Environmental transmission of SARS at Amoy Gardens.
McKinney, K. R., Gong, Y. Y., & Lewis, T. G. (2006) · PubMed · Cited by 195 · see citing works
Li, Y., Duan, S., Yu, I. T. S., & Wong, T. W. (2005) · Indoor Air · doi:10.1111/j.1600-0668.2004.00318.x · Cited by 190 · see citing works
THE CLOUD ADULT: THE STAPHYLOCOCCUS AUREUS-VIRUS INTERACTION REVISITED.
&NA; (1997) · The Pediatric Infectious Disease Journal · doi:10.1097/00006454-199705000-00038 · Cited by 169 · see citing works
SARS: experience at Prince of Wales Hospital, Hong Kong
Tomlinson, B., & Cockram, C. S. (2003) · The Lancet · doi:10.1016/s0140-6736(03)13218-7 · Cited by 162 · see citing works
Moss, G. B., Overbaugh, J. M., Welch, M., Reilly, M., Bwayo, J. J., Plummer, F., Ndinya‐Achola, J. O., Malisa, M., & Kreiss, J. (1995) · The Journal of Infectious Diseases · doi:10.1093/infdis/172.6.1469 · Cited by 148 · see citing works
Models of Infectious Diseases in Spatially Heterogeneous Environments
RodrÍguez, D. (2001) · Bulletin of Mathematical Biology · doi:10.1006/bulm.2001.0231 · Cited by 125 · see citing works
Severe acute respiratory syndrome--Singapore, 2003.
(2003) · PubMed · Cited by 116 · see citing works
The "Cloud Baby": An Example of Bacterial-Viral Interaction
Eichenwald, H. F. (1960) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.1960.04020040163003 · Cited by 103 · see citing works
Paunio, M., Peltola, H., Valle, M., Davidkin, I., Virtanen, M. A., & Heinonen, O. P. (1998) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009588 · Cited by 103 · see citing works
Li, Y. (2004) · American Journal of Epidemiology · doi:10.1093/aje/kwh273 · Cited by 101 · see citing works
Severe acute respiratory syndrome (SARS): epidemiology and clinical features
Hui, D. S. C., Chan, M. C. W., Wu, A. K. L., & Ng, P. C. (2004) · Postgraduate Medical Journal · doi:10.1136/pgmj.2004.020263 · Cited by 93 · see citing works
Lack of SARS Transmission among Public Hospital Workers, Vietnam
Hà, L. D., Bloom, S. A., Hien, N. Q., Maloney, S. A., Quynh, L. T., Leitmeyer, K. C., Anh, B. H., Reynolds, M. G., Montgomery, J. M., Comer, J. A., et al. (2004) · Emerging infectious diseases · doi:10.3201/eid1002.030707 · Cited by 93 · see citing works
Contact heterogeneity in deer mice: implications for Sin Nombre virus transmission
Clay, C. A., Lehmer, E. M., Previtali, M. A., Jeor, S. S., & Dearing, M. D. (2009) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2008.1693 · Cited by 82 · see citing works
Dispersal ofStaphylococcus aureusInto the Air Associated With a Rhinovirus Infection
Bassetti, S., Bischoff, W. E., Walter, M. K., Bassetti-Wyss, B. A., Mason, L., Reboussin, B. A., Agostino, R. B. D., Gwaltney, J. M., Pfaller, M. A., & Sherertz, R. J. (2005) · Infection Control and Hospital Epidemiology · doi:10.1086/502526 · Cited by 80 · see citing works
Genital Herpes Simplex Virus Infection and Perinatal Transmission of Human Immunodeficiency Virus
Chen, K. T., Segú, M., Lumey, L. H., Kuhn, L., Carter, R. J., Bulterys, M., & Abrams, E. J. (2005) · Obstetrics and Gynecology · doi:10.1097/01.aog.0000185917.90004.7c · Cited by 74 · see citing works
Asymptomatic urethritis and detection of HIV-1 RNA in seminal plasma
Winter, A. J., Taylor, S. R., Workman, J., White, D., Ross, J. D. C., Swan, A. V., & Pillay, D. (1999) · Sexually Transmitted Infections · doi:10.1136/sti.75.4.261 · Cited by 68 · see citing works
Muñoz, F. M., Ong, L. T., Seavy, D., Medina, D., Correa, A. G., & Starke, J. R. (2002) · Infection Control and Hospital Epidemiology · doi:10.1086/501972 · Cited by 56 · see citing works
Transmission of mycobacterium tuberculosis to and from children and adolescents
Starke, J. R. (2001) · Seminars in Pediatric Infectious Diseases · doi:10.1053/spid.2001.22785 · Cited by 54 · see citing works
Neck sprain. Associated factors
Farbman, A. A. (1973) · JAMA · doi:10.1001/jama.223.9.1010 · Cited by 54 · see citing works
Bollen, L. J. M., Whitehead, S. J., Mock, P. A., Leelawiwat, W., Asavapiriyanont, S., Chalermchockcharoenkit, A., Vanprapar, N., Chotpitayasunondh, T., McNicholl, J. M., Tappero, J. W., et al. (2008) · AIDS · doi:10.1097/qad.0b013e3282fec42a · Cited by 49 · see citing works
The sad and tragic life of Typhoid Mary.
Brooks, J. (1996) · PubMed · Cited by 48 · see citing works
Cruz, A. T., Medina, D., Whaley, E. M., Ware, K. M., Koy, T. H., & Starke, J. R. (2011) · Infection Control and Hospital Epidemiology · doi:10.1086/657940 · Cited by 47 · see citing works
Heterogeneous shedding ofBrucella abortusin milk and its effect on the control of animal brucellosis
Capparelli, R., Parlato, M., Iannaccone, M., Roperto, S., Marabelli, R., Roperto, F. P., & Iannelli, D. (2009) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2009.04177.x · Cited by 46 · see citing works
Outbreak of Staphylococcal Infection in Two Hospital Nurseries Traced to a Single Nasal Carrier
Belani, A., Sherertz, R. J., Sullivan, M. L., Russell, B. A., & Reumen, P. D. (1986) · Infection Control · doi:10.1017/s0195941700065097 · Cited by 45 · see citing works
Uremia impairs blood dendritic cell function in hemodialysis patients
Lim, W. H., Kireta, S., Russ, G. R., & Coates, P. T. (2007) · Kidney International · doi:10.1038/sj.ki.5002196 · Cited by 42 · see citing works
Rubella in an Immunized Island Population
Hattis, R. P. (1973) · JAMA · doi:10.1001/jama.1973.03220090039008 · Cited by 41 · see citing works
Are SARS Superspreaders Cloud Adults?
Bassetti, S., Bischoff, W. E., & Sherertz, R. J. (2005) · Emerging infectious diseases · doi:10.3201/eid1104.040639 · Cited by 40 · see citing works
The SARS outbreak in a general hospital in Tianjin, China – the case of super-spreader
WANG, S. X., Li, Y., Sun, B., ZHANG, S. W., Zhao, W., Wei, M., Chen, K., Zhao, X., Zhang, Z. L., Krahn, M. D., et al. (2005) · Epidemiology and Infection · doi:10.1017/s095026880500556x · Cited by 40 · see citing works
“Gesundheit!” Sneezing, Common Colds, Allergies, andStaphylococcus aureusDispersion
Bischoff, W. E., Wallis, M. L., Tucker, B. K., Reboussin, B. A., Pfaller, M. A., Hayden, F. G., & Sherertz, R. J. (2006) · The Journal of Infectious Diseases · doi:10.1086/507908 · Cited by 39 · see citing works
Bischoff, W. E., Bassetti, S., Bassetti-Wyss, B. A., Wallis, M. L., Tucker, B. K., Reboussin, B. A., D'Agostino, R. B., Pfaller, M. A., Gwaltney, J. M., & Sherertz, R. J. (2004) · Infection Control and Hospital Epidemiology · doi:10.1086/502430 · Cited by 22 · see citing works
Abernathy, R. S. (1997) · Pediatrics in Review · doi:10.1542/pir.18-2-50 · Cited by 17 · see citing works
Wu, W., Wang, J.-F., Liu, P. M., Jiang, S., Chen, Q.-Y., Chen, W. X., Yin, S. M., Li, Y., Zhan, J., Chen, X.-L., et al. (2004) · PubMed · Cited by 9 · see citing works
Unusually high HIV infectiousness in an HIV-, HCV- and HSV-2-coinfected heterosexual man
Yerly, S. (2009) · Swiss Medical Weekly · doi:10.4414/smw.2009.12575 · Cited by 9 · see citing works
Flagged first, then by citations
1 of the 53 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Return of the Coronavirus: 2019-nCoV
Gralinski, L. E., & Menachery, V. D. (2020) · Viruses · doi:10.3390/v12020135 · Cited by 1,348 · see citing works
Aerosol Emission and Superemission during Human Speech Increase with Voice Loudness
Asadi, S., Wexler, A. S., Cappa, C. D., Barreda, S., Bouvier, N. M., & Ristenpart, W. D. (2019) · Scientific Reports · doi:10.1038/s41598-019-38808-z · Cited by 919 · see citing works
Transmission routes of respiratory viruses among humans
Kutter, J. S., Spronken, M. I., Fraaij, P. L., Fouchier, R. A., & Herfst, S. (2018) · Current Opinion in Virology · doi:10.1016/j.coviro.2018.01.001 · Cited by 611 · see citing works
Jones, D. L., Baluja, M. Q., Graham, D. W., Corbishley, A., McDonald, J. E., Malham, S. K., Hillary, L. S., Connor, T. R., Gaze, W. H., Moura, I. B., et al. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.141364 · Cited by 394 · see citing works
Fung, S., Yuen, K., Ye, Z., Chan, C., & Jin, D. (2020) · Emerging Microbes & Infections · doi:10.1080/22221751.2020.1736644 · Cited by 383 · see citing works
COVID-19: Facts, Cultural Considerations, and Risk of Stigmatization
Bruns, D. P., Kraguljac, N. V., & Bruns, T. R. (2020) · Journal of Transcultural Nursing · doi:10.1177/1043659620917724 · Cited by 289 · see citing works
MERS transmission and risk factors: a systematic review
Park, J., Jung, S., Kim, A., & Park, J. (2018) · BMC Public Health · doi:10.1186/s12889-018-5484-8 · Cited by 284 · see citing works
Heterogeneity in pathogen transmission: mechanisms and methodology
VanderWaal, K., & Ezenwa, V. (2016) · Functional Ecology · doi:10.1111/1365-2435.12645 · Cited by 234 · see citing works
Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea, 2015
Prevention, K. C. F. D. C. A. (2015) · Osong Public Health and Research Perspectives · doi:10.1016/j.phrp.2015.08.006 · Cited by 259 · see citing works
"Super-Spreaders" and Person-to-Person Transmission of Andes Virus in Argentina
Martínez, V. P., Di Paola, N., Alonso, D. O., Pérez-Sautu, U., Bellomo, C. M., Iglesias, A. A., Coelho, R. M., López, B., Periolo, N., Larson, P. A., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2009040 · Cited by 247 · see citing works
Cluster of Coronavirus Disease 2019 (COVID-19) in the French Alps, February 2020
Danis, K., Épaulard, O., Bénet, T., Gaymard, A., Campoy, S., Botelho-Nevers, É., Bouscambert‐Duchamp, M., Spaccaferri, G., Ader, F., Mailles, A., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa424 · Cited by 233 · see citing works
Animal models for influenza virus pathogenesis, transmission, and immunology
Thangavel, R. R., & Bouvier, N. M. (2014) · Journal of Immunological Methods · doi:10.1016/j.jim.2014.03.023 · Cited by 185 · see citing works
Shedding light on Salmonella carriers
Gopinath, S., Carden, S., & Monack, D. M. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2012.04.004 · Cited by 164 · see citing works
Ghinai, I., Woods, S., Ritger, K. A., McPherson, T. D., Black, S. R., Sparrow, L., Fricchione, M. J., Kerins, J. L., Pacilli, M., Ruestow, P., et al. (2020) · MMWR Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm6915e1 · Cited by 144 · see citing works
Richard, M., & Fouchier, R. A. M. (2015) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuv039 · Cited by 134 · see citing works
Courtenay, O., Carson, C., Calvo-Bado, L. A., Garcez, L. M., & Quinnell, R. J. (2014) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0002583 · Cited by 123 · see citing works
Sneppen, K., Nielsen, B. F., Taylor, R. J., & Simonsen, L. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2016623118 · Cited by 117 · see citing works
Iacono, G. L., Cunningham, A. A., Fichet-Calvet, É., Garry, R. F., Grant, D. S., Khan, S. H., Leach, M., Moses, L., Schieffelin, J. S., Shaffer, J. G., et al. (2015) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0003398 · Cited by 117 · see citing works
Swine as a Model for Influenza A Virus Infection and Immunity
Rajão, D. S., & Vincent, A. L. (2015) · ILAR Journal · doi:10.1093/ilar/ilv002 · Cited by 113 · see citing works
Correa-Martínez, C. L., Kampmeier, S., Kümpers, P., Schwierzeck, V., Hennies, M. T., Hafezi, W., Kühn, J., Pavenstädt, H. J., Ludwig, S., & Mellmann, A. (2020) · Journal of Clinical Microbiology · doi:10.1128/jcm.00588-20 · Cited by 112 · see citing works
COVID-19: A Risk Assessment Perspective
Schröder, I. (2020) · ACS Chemical Health & Safety · doi:10.1021/acs.chas.0c00035 · Cited by 112 · see citing works
Role of fomites in SARS transmission during the largest hospital outbreak in Hong Kong
Xiao, S., Li, Y., Wong, T.-W., & Hui, D. S. C. (2017) · PLoS ONE · doi:10.1371/journal.pone.0181558 · Cited by 108 · see citing works
Mapping genome variation of SARS-CoV-2 worldwide highlights the impact of COVID-19 super-spreadersPreprint
Gómez‐Carballa, A., Bello, X., Pardo‐Seco, J., Martinón‐Torres, F., & Salas, A. (2020) · Genome Research · doi:10.1101/gr.266221.120 · Cited by 107 · see citing works
Nosocomial infection of COVID‑19: A new challenge for healthcare professionals (Review)
Du, Q., Zhang, D., Hu, W., Li, X., Xia, Q., Wen, T., & Jia, H. (2021) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2021.4864 · Cited by 105 · see citing works
Pathways for Novel Epidemiology: Plant–Pollinator–Pathogen Networks and Global Change
Proesmans, W., Albrecht, M., Gajda, A. M., Neumann, P., Paxton, R. J., Pioz, M., Polzin, C., Schweiger, O., Settele, J., Szentgyörgyi, H., et al. (2021) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2021.03.006 · Cited by 102 · see citing works
Exposure Patterns Driving Ebola Transmission in West Africa: A Retrospective Observational Study
International Ebola Response Team, Agua-Agum, J., Ariyarajah, A., Aylward, B., Bawo, L., Bilivogui, P., Blake, I. M., Brennan, R. J., Cawthorne, A., Cleary, E., et al. (2016) · PLoS Medicine · doi:10.1371/journal.pmed.1002170 · Cited by 101 · see citing works
Evaluating Transmission Heterogeneity and Super-Spreading Event of COVID-19 in a Metropolis of China
Zhang, Y., Li, Y., Wang, L., Li, M., & Zhou, X. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17103705 · Cited by 100 · see citing works
Lerner, A. O., Adler, A., Abu-Hanna, J., Percia, S. C., Kazma, M., & Carmeli, Y. (2014) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2014.12.015 · Cited by 99 · see citing works
Infectious Diseases as Socio‐Spatial Processes: The COVID‐19 Outbreak In Germany
Kuebart, A., & Stabler, M. (2020) · Tijdschrift voor Economische en Sociale Geografie · doi:10.1111/tesg.12429 · Cited by 97 · see citing works
A novel methodology for epidemic risk assessment of COVID-19 outbreak
Pluchino, A., Biondo, A. E., Giuffrida, N., Inturri, G., Latora, V., Moli, R. L., Rapisarda, A., Russo, G., & Zappalà, C. (2021) · Scientific Reports · doi:10.1038/s41598-021-82310-4 · Cited by 96 · see citing works
Lee, J., Chowell, G., & Jung, E. (2016) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2016.08.009 · Cited by 94 · see citing works
Kang, C. K., Song, K., Choe, P. G., Park, W. B., Bang, J. H., Kim, E. S., Park, S., Kim, H. B., Kim, N. J., Cho, S., et al. (2017) · Journal of Korean Medical Science · doi:10.3346/jkms.2017.32.5.744 · Cited by 93 · see citing works
Avery, C. N., Bossert, W. H., Clark, A. T., Ellison, G., & Ellison, S. F. (2020) · National Bureau of Economic Research · doi:10.3386/w27007 · Cited by 93 · see citing works
Tacaribe Virus Causes Fatal Infection of An Ostensible Reservoir Host, the Jamaican Fruit Bat
Hawkinson, A., Bowen, R. A., James, S. F., Gardiner, D. W., Calisher, C. H., Adams, R. A., & Schountz, T. (2012) · Journal of Virology · doi:10.1128/jvi.00201-12 · Cited by 88 · see citing works
Fontes, D. H., Reyes, J., Ahmed, K. A., & Kinzel, M. (2020) · Physics of Fluids · doi:10.1063/5.0032006 · Cited by 87 · see citing works
Cancer: a missing link in ecosystem functioning?
Vittecoq, M., Roche, B., Daoust, S. P., Ducasse, H., Missé, D., Abadie, J., Labrut, S., François Renaud, A., Gauthier‐Clerc, M., & Frédéric Thomas, A. (2013) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2013.07.005 · Cited by 87 · see citing works
Heterogeneous hosts: how variation in host size, behaviour and immunity affects parasite aggregation
Johnson, P. T. J., & Hoverman, J. T. (2014) · Journal of Animal Ecology · doi:10.1111/1365-2656.12215 · Cited by 83 · see citing works
Lee, J. Y., Kim, Y.-J., Chung, E. H., Kim, D.-W., Jeong, I., Kim, Y., Yun, M.-R., Kim, S. S., Kim, G., & Joh, J.-S. (2017) · BMC Infectious Diseases · doi:10.1186/s12879-017-2576-5 · Cited by 83 · see citing works
Mathematical and computational approaches to epidemic modeling: a comprehensive review
Duan, W., Fan, Z., Zhang, P., Guo, G., & Qiu, X. (2015) · Frontiers of Computer Science · doi:10.1007/s11704-014-3369-2 · Cited by 82 · see citing works
Enriquez, G. F., Búa, J., Orozco, M., Wirth, S. A., Schijman, A. G., Gürtler, R. E., & Cardinal, M. V. (2014) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2014.04.002 · Cited by 80 · see citing works
Human Extinction and the Pandemic Imaginary
Lynteris, C. (2019) · Routledge eBooks · doi:10.4324/9780429322051 · Cited by 79 · see citing works
Rajakaruna, S. J., Liu, W., Ding, Y., & Cao, G. (2017) · Military Medical Research · doi:10.1186/s40779-017-0142-5 · Cited by 76 · see citing works
COVID-19 Super-spreaders: Definitional Quandaries and Implications
Cave, E. (2020) · Asian Bioethics Review · doi:10.1007/s41649-020-00118-2 · Cited by 76 · see citing works
Health Care Workers and Patients as Trojan Horses: a COVID19 ward outbreak
Asad, H., Johnston, C., Blyth, I., Holborow, A., Bone, A., Porter, L., Tidswell, P., & Healy, B. G. (2020) · Infection Prevention in Practice · doi:10.1016/j.infpip.2020.100073 · Cited by 71 · see citing works
Work, T. M., Dagenais, J., Balazs, G. H., Schetle, N., & Ackermann, M. (2014) · Veterinary Pathology · doi:10.1177/0300985814560236 · Cited by 71 · see citing works
Mucins Inhibit Coronavirus Infection in a Glycan-Dependent Manner
Wardzala, C. L., Wood, A. M., Belnap, D. M., & Kramer, J. R. (2022) · ACS Central Science · doi:10.1021/acscentsci.1c01369 · Cited by 68 · see citing works
The Impact of Ventilation and Early Diagnosis on Tuberculosis Transmission in Brazilian Prisons
Urrego, J., Ko, A. I., Carbone, A. D. S. S., Paião, D. S. G., Sgarbi, R. V. E., Yeckel, C. W., Andrews, J. R., & Croda, J. (2015) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.15-0166 · Cited by 67 · see citing works
Characterizing super-spreading in microblog: An epidemic-based information propagation model
Liu, Y., Wang, B., Wu, B., Shang, S., Zhang, Y., & Shi, C. (2016) · Physica A Statistical Mechanics and its Applications · doi:10.1016/j.physa.2016.07.022 · Cited by 65 · see citing works
Lau, L. L., Ip, D., Nishiura, H., Fang, V. J., Chan, K., Peiris, M. J. S., Leung, G. M., & Cowling, B. J. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit034 · Cited by 63 · see citing works
Beldoménico, P. M. (2020) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2020.05.025 · Cited by 62 · see citing works
Understanding host utilization by mosquitoes: determinants, challenges and future directions
Yan, J., Gangoso, L., Ruíz, S., Soriguer, R. C., Figuerola, J., & la Puente, J. M. (2021) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12706 · Cited by 62 · see citing works
Final Size of an Epidemic for a Two-Group SIR Model
Magal, P., Seydi, O., & Webb, G. F. (2016) · SIAM Journal on Applied Mathematics · doi:10.1137/16m1065392 · Cited by 60 · see citing works
Chen, Z., Zhang, W., Lu, Y., Guo, C., Guo, Z., Liao, C., Zhang, X., Zhang, Y., Han, X., Li, Q., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.01.24.919241 · Cited by 60 · see citing works
RetractedResource limitation alters the consequences of co-infection for both hosts and parasites
Budischak, S. A., Sakamoto, K., Megow, L. C., Cummings, K. R., Urban, J. F., & Ezenwa, V. O. (2015) · International Journal for Parasitology · doi:10.1016/j.ijpara.2015.02.005 · Cited by 59 · see citing works
Kim, S. W., Park, J. W., Jung, H., Yang, J., Park, Y.-S., Lee, C., Kim, K. M., Lee, K., Kwon, D., Hur, Y. J., et al. (2016) · Clinical Infectious Diseases · doi:10.1093/cid/ciw768 · Cited by 58 · see citing works
O’Connell, K., Berluti, K., Rhoads, S. A., & Marsh, A. A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0244974 · Cited by 57 · see citing works
Aiello, C. M., Nussear, K. E., Esque, T. C., Emblidge, P., Sah, P., Bansal, S., & Hudson, P. J. (2016) · Journal of Animal Ecology · doi:10.1111/1365-2656.12511 · Cited by 54 · see citing works
Kim, Y., Ryu, H., & Lee, S. (2018) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15112369 · Cited by 54 · see citing works
Chapter 2: Transmission and pathogenesis of tuberculosis
Long, R., Divangahi, M., & Schwartzman, K. (2022) · Canadian Journal of Respiratory Critical Care and Sleep Medicine · doi:10.1080/24745332.2022.2035540 · Cited by 54 · see citing works
Bak, A., Mugglestone, M. A., Ratnaraja, N., Wilson, J. A., Rivett, L., Stoneham, S. M., Bostock, J., Moses, S. E., Price, J. R., Weinbren, M. J., et al. (2021) · Journal of Hospital Infection · doi:10.1016/j.jhin.2021.04.027 · Cited by 53 · see citing works
Lorch, L., Kremer, H., Trouleau, W., Tsirtsis, S., Szanto, A., Schölkopf, B., & Gomez-Rodriguez, M. (2022) · ACM Transactions on Spatial Algorithms and Systems · doi:10.1145/3530774 · Cited by 51 · see citing works
Differential attraction in mosquito–human interactions and implications for disease control
Martinez, J., Showering, A., Oke, C. E., Jones, R. G., & Logan, J. G. (2020) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2019.0811 · Cited by 51 · see citing works
Pruvot, M., Khammavong, K., Milavong, P., Philavong, C., Reinharz, D., Mayxay, M., Rattanavong, S., Horwood, P. F., Dussart, P., Douangngeun, B., et al. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.04.266 · Cited by 49 · see citing works
Previously undetected super-spreading of Mycobacterium tuberculosis revealed by deep sequencing
Lee, R. S., Proulx, J., McIntosh, F. A., Behr, M. A., & Hanage, W. P. (2020) · eLife · doi:10.7554/elife.53245 · Cited by 49 · see citing works
Charbonnel, N., Pagès, M., Sironen, T. A., Henttonen, H. A., Vapalahti, O., Mustonen, J. T., & Vaheri, A. I. (2014) · Viruses · doi:10.3390/v6052214 · Cited by 48 · see citing works
Zemenick, A. T., Vannette, R. L., & Rosenheim, J. A. (2021) · Oikos · doi:10.1111/oik.06818 · Cited by 48 · see citing works
Grant, C., Iacono, G. L., Dzingirai, V., Bett, B., Winnebah, T. R. A., & Atkinson, P. M. (2016) · Infectious Diseases of Poverty · doi:10.1186/s40249-016-0110-4 · Cited by 47 · see citing works
Adriaensen, W. J., Dorlo, T. P. C., Vanham, G., Kestens, L., Kaye, P. M., & van Griensven, J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01943 · Cited by 46 · see citing works
Ćwiek, K., Korzekwa, K., Tabiś, A., Bania, J., Bugla‐Płoskońska, G., & Wieliczko, A. (2020) · Pathogens · doi:10.3390/pathogens9080643 · Cited by 46 · see citing works
Kinetics of Immune Responses in Deer Mice Experimentally Infected with Sin Nombre Virus
Schountz, T., Acuña-Retamar, M., Feinstein, S., Prescott, J. B., Torres‐Pérez, F., Podell, B. K., Peters, S., Ye, C., Black, W. C., & Hjelle, B. L. (2012) · Journal of Virology · doi:10.1128/jvi.06875-11 · Cited by 44 · see citing works
Impact of mobility restriction in COVID-19 superspreading events using agent-based model
Lima, L. L., & Atman, A. P. F. (2021) · PLoS ONE · doi:10.1371/journal.pone.0248708 · Cited by 43 · see citing works
Melsew, Y. A., Gambhir, M., Cheng, A. C., McBryde, E. S., Denholm, J. T., Tay, E. L., & Trauer, J. M. (2019) · BMC Infectious Diseases · doi:10.1186/s12879-019-3870-1 · Cited by 43 · see citing works
GSI: An Influential Node Detection Approach in Heterogeneous Network Using Covid-19 as Use Case
Shetty, R. D., Bhattacharjee, S., Dutta, A., & Namtirtha, A. (2022) · IEEE Transactions on Computational Social Systems · doi:10.1109/tcss.2022.3180177 · Cited by 42 · see citing works
Communicable Disease Surveillance Ethics in the Age of Big Data and New Technology
Gilbert, G. L., Degeling, C., & Johnson, J. (2019) · Asian Bioethics Review · doi:10.1007/s41649-019-00087-1 · Cited by 42 · see citing works
The daily impact of COVID‐19 in gastroenterology
Magro, F., Abreu, C., & Rahier, J. (2020) · United European Gastroenterology Journal · doi:10.1177/2050640620920157 · Cited by 41 · see citing works
Inexpensive and fast pathogenic bacteria screening using field-effect transistors
Formisano, N., Bhalla, N., Heeran, M. C., Reyes-Martínez, J. E., Sarkar, A., Laabei, M., Jolly, P., Bowen, C., Taylor, J. T., Flitsch, S. L., et al. (2016) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2016.04.063 · Cited by 41 · see citing works
Friedler, A. (2020) · Global Public Health · doi:10.1080/17441692.2020.1828982 · Cited by 41 · see citing works
Cota, W., Soriano‐Paños, D., Arenas, A., Ferreira, S. C., & Gómez‐Gardeñes, J. (2021) · New Journal of Physics · doi:10.1088/1367-2630/ac0c99 · Cited by 41 · see citing works
Yu, P.-D., Tan, C. W., & Fu, H. (2022) · IEEE Journal of Selected Topics in Signal Processing · doi:10.1109/jstsp.2022.3153168 · Cited by 41 · see citing works
Magal, P., Seydi, O., & Webb, G. F. (2018) · Mathematical Biosciences · doi:10.1016/j.mbs.2018.03.020 · Cited by 40 · see citing works
Superspreading in the emergence of COVID-19 variants
Gómez‐Carballa, A., Pardo‐Seco, J., Bello, X., Martinón‐Torres, F., & Salas, A. (2021) · Trends in Genetics · doi:10.1016/j.tig.2021.09.003 · Cited by 39 · see citing works
Spatial super-spreaders and super-susceptibles in human movement networks
Chin, W. C. B., & Bouffanais, R. (2020) · Scientific Reports · doi:10.1038/s41598-020-75697-z · Cited by 39 · see citing works
Routes of Transmission in the Food Chain
Stein, R. A., & Chirilă, M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-385007-2.00003-6 · Cited by 37 · see citing works
Self-citationHulme, P. E., Baker, R., Freckleton, R. P., Hails, R. S., Hartley, M., Harwood, J., Marion, G., Smith, G. C., & Williamson, M. (2020) · NeoBiota · doi:10.3897/neobiota.62.52463 · Cited by 37 · see citing works
Ladoy, A., Opota, O., Carron, P., Guessous, I., Vuilleumier, S., Joost, S., & Greub, G. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.147483 · Cited by 37 · see citing works
Host heterogeneity affects both parasite transmission to and fitness on subsequent hosts
Stephenson, J. F., Young, K. A., Fox, J., Jokela, J., Cable, J., & Perkins, S. E. (2017) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2016.0093 · Cited by 35 · see citing works
Biemans, F., de Jong, M. C. M., & Bijma, P. (2017) · Genetics Selection Evolution · doi:10.1186/s12711-017-0327-0 · Cited by 35 · see citing works
Halting SARS-CoV-2 by Targeting High-Contact Individuals
Manzo, G., & van de Rijt, A. (2020) · Journal of Artificial Societies and Social Simulation · doi:10.18564/jasss.4435 · Cited by 35 · see citing works
Ng, T.-C. V., & Wen, T. (2019) · Scientific Reports · doi:10.1038/s41598-019-55574-0 · Cited by 34 · see citing works
Sarkar, K., Sarkar, B., & Sinha, R. (2020) · Indian Journal of Community Medicine · doi:10.4103/ijcm.ijcm_593_20 · Cited by 34 · see citing works
Novel 2019 coronavirus: Genome structure, clinical trials, and outstanding questions
Jogalekar, M. P., Veerabathini, A., & Gangadaran, P. (2020) · Experimental Biology and Medicine · doi:10.1177/1535370220920540 · Cited by 33 · see citing works
Catch Me if You Can: Superspreading of COVID-19
Lakdawala, S. S., & Menachery, V. D. (2021) · Trends in Microbiology · doi:10.1016/j.tim.2021.05.002 · Cited by 33 · see citing works
Beucher, G., Blondot, M.-L., Celle, A., Pied, N., Recordon-Pinson, P., Estèves, P., Faure, M., Métifiot, M., Lacomme, S., Dacheux, D., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2202370119 · Cited by 33 · see citing works
Li, H. J., Burm, S. W., Hong, S. H., Ghayda, R. A., Kronbichler, A., Smith, L., Koyanagi, A., Jacob, L., Lee, K. H., & Shin, J. I. (2020) · Yonsei Medical Journal · doi:10.3349/ymj.2021.62.1.1 · Cited by 32 · see citing works
Bisanzio, D., Reithinger, R., Alqunaibet, A., Almudarra, S., Alsukait, R. F., Dong, D., Zhang, Y., El-Saharty, S., & Herbst, C. H. (2022) · BMC Medicine · doi:10.1186/s12916-022-02232-4 · Cited by 32 · see citing works
Social immunity modulates competition between coinfecting pathogens
Milutinović, B., Stock, M., Grasse, A. V., Naderlinger, E., Hilbe, C., & Cremer, S. (2020) · Ecology Letters · doi:10.1111/ele.13458 · Cited by 31 · see citing works
Romeo, C., Wauters, L. A., Santicchia, F., Dantzer, B., Palme, R., Martinoli, A., & Ferrari, N. (2020) · Current Zoology · doi:10.1093/cz/zoaa029 · Cited by 31 · see citing works
Pandey, A. P., Nikam, A. N., Mutalik, S. P., Fernandes, G. J., Shreya, A. B., Padya, B. S., Raychaudhuri, R., Kulkarni, S., Prassl, R., Subramanian, S., et al. (2020) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.0c01243 · Cited by 31 · see citing works
Does landscape connectivity shape local and global social network structure in white-tailed deer?
Koen, E. L., Tosa, M. I., Nielsen, C. K., & Schauber, E. M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0173570 · Cited by 31 · see citing works
Gopinath, S., Hotson, A. N., Johns, J. L., Nolan, G. P., & Monack, D. M. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003408 · Cited by 30 · see citing works
- Authors
- Stein, R. A.
- Affiliations
- Princeton University (US)
- Corresponding author
- Stein, Richard A.
- ORCID
- Stein, Richard A.
- Venue
- International Journal of Infectious Diseases
- Publisher
- Elsevier BV
- Published
- 2011-08
- Volume
- 15
- Issue
- 8
- Pages
- e510-e513
- ISSN
- 1201-9712 (ISSN-L)
- PMC
- PMC7110524
- OpenAlex
- W2007300619
- Cited by
- 388
- References
- 53
- Citations by year
- 2026: 18 · 2025: 17 · 2024: 23 · 2023: 16 · 2022: 44 · 2021: 61 · 2020: 90 · 2019: 24 · 2018: 16 · 2017: 15 · 2016: 18 · 2015: 22 · 2014: 12 · 2013: 8 · 2012: 4
- FWCI
- 8.40
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of Infectious Diseases (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Mathematics › Modeling and Simulation › COVID-19 epidemiological studies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Mathematical and Theoretical Epidemiology and Ecology Models
- Health Sciences › Medicine › Infectious Diseases › Viral Infections and Outbreaks Research
- Keywords
- superspreaders, superspreading events, Pareto principle, SARS, infectious disease transmission, host-pathogen interaction, co-infection, immunosuppression, airflow dynamics, misdiagnosis, interhospital transfer, pandemic preparedness, transmission dynamics
- MeSH terms
- Animals, Communicable Diseases, Environment, Humans, Public Health, Severe Acute Respiratory Syndrome, Host-Pathogen Interactions, Pandemics, Coinfection
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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