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Cited by 200

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

The Maxwell Finland Lecture: For the Duration-- Rational Antibiotic Administration in an Era of Antimicrobial Resistance and Clostridium difficile

Rice, L. B.·2008·Clinical Infectious Diseases

Abstract

Antimicrobial resistance is frequently associated with clinical use of antibiotics. This close association suggests that efforts to manage our use of these potent agents can have an impact on the prevalence of resistance. Unfortunately, one size does not fit all when considering the response of bacterial pathogens to antimicrobial exposure. Measures that may prevent resistance in some species (such as using multiple antibiotics to treat tuberculosis) may exacerbate the problem of resistance in others (such as Pseudomonas aeruginosa or Acinetobacter baumannii). The simplest approach is to use fewer antibiotics and thereby apply less selective pressure to the prevalent flora. Among available strategies to reduce use, reductions in length of antimicrobial regimens are the safest and are likely to be the most palatable to practicing clinicians. Studies are urgently needed to define minimal lengths of therapy to ensure that efforts at reduced use are safe and effective.

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Metadata

Authors
Rice, L. B.
Venue
Clinical Infectious Diseases
Published
2008-02-15
Volume
46
Issue
4
Pages
491-496
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W2123875999
Cited by
200
References
3
FWCI
11.03
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Maxwell Finland Lecture: For the Duration-- Rational Antibiotic Administration in an Era of Antimicrobial Resistance and Clostridium difficile. https://app.cochat.ai/papers/10.1086/526535
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Rice, L. B. (2008). The Maxwell Finland Lecture: For the Duration-- Rational Antibiotic Administration in an Era of Antimicrobial Resistance and Clostridium difficile. Clinical Infectious Diseases. https://doi.org/10.1086/526535

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.